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Disease mapping is the field of spatial epidemiology interested in estimating the spatial pattern in disease risk across $n$ areal units. One aim is to identify units exhibiting elevated disease risks, so that public health interventions…
This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…
Principled decision making in emergency response management necessitates the use of statistical models that predict the spatial-temporal likelihood of incident occurrence. These statistical models are then used for proactive stationing…
Spatially referenced data are increasingly available thanks to the development of modern GPS technology. They also provide rich opportunities for spatial analytics in the field of marketing science. Our main interest is to propose a new…
Quantifying spatial and/or temporal associations in multivariate geolocated data of different types is achievable via spatial random effects in a Bayesian hierarchical model, but severe computational bottlenecks arise when spatial…
Spatio-temporal systems exhibiting multi-scale behaviour are common in applications ranging from cyber-physical systems to systems biology, yet they present formidable challenges for computational modelling and analysis. Here we consider a…
The joint modeling of longitudinal and time-to-event outcomes has become a popular tool in follow-up studies. However, fitting Bayesian joint models to large datasets, such as patient registries, can require extended computing times. To…
Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…
Cloud-to-ground lightning strikes observed in a specific geographical domain over time can be naturally modeled by a spatio-temporal point process. Our focus lies in the parametric estimation of its intensity function, incorporating both…
We develop a test of normality for spatially indexed functions. The assumption of normality is common in spatial statistics, yet no significance tests, or other means of assessment, have been available for functional data. This paper aims…
In regression-based analyses of group-level neuroimage data researchers typically fit a series of marginal general linear models to image outcomes at each spatially-referenced pixel. Spatial regularization of effects of interest is usually…
To meet the Basel II regulatory requirements for the Advanced Measurement Approaches, the bank's internal model must include the use of internal data, relevant external data, scenario analysis and factors reflecting the business environment…
One way of characterizing the topological and structural properties of vertices and edges in a graph is by using structural similarity measures. Measures like Cosine, Jaccard and Dice compute the similarities restricted to the immediate…
Measuring the causal impact of an advertising campaign on sales is an essential task for advertising companies. Challenges arise when companies run advertising campaigns in multiple stores which are spatially correlated, and when the sales…
Spatio-temporal extensions of familiar compartment models for disease transmission incorporating diffusive behavior, or interactions between individuals at separate locations, are explored. The models considered have the character of…
Bayesian model-based spatial clustering methods are widely used for their flexibility in estimating latent clusters with an unknown number of clusters while accounting for spatial proximity. Many existing methods are designed for clustering…
We propose a Bayesian hierarchical model to address the challenge of spatial misalignment in spatio-temporal data obtained from in situ and satellite sources. The model is fit using the INLA-SPDE approach, which provides efficient…
The advent of data science has provided an increasing number of challenges with high data complexity. This paper addresses the challenge of space-time data where the spatial domain is not a planar surface, a sphere, or a linear network, but…
Spatio-temporal pathogen spread is often partially observed at the metapopulation scale. Available data correspond to proxies and are incomplete, censored and heterogeneous. Moreover, representing such biological systems often leads to…
The algorithms used for the optimal management of an ambulance fleet require an accurate description of the spatio-temporal evolution of the emergency events. In the last years, several authors have proposed sophisticated statistical…