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Introduction The tau statistic is a recent second-order correlation function that can assess the magnitude and range of global spatiotemporal clustering from epidemiological data containing geolocations of individual cases and, usually,…
Shared frailty models have been proposed to accommodate unmeasured cluster-specific risk factors through the inclusion of a common latent frailty term. Among possible frailty distributions, the Gamma distribution is appealing due to its…
This manuscript unites causal inference and spatial statistics, presenting novel insights for causal inference in spatial data analysis, and drawing from tools in spatial statistics to estimate causal effects. We introduce spatial causal…
Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…
In public health applications, spatial data collected are often recorded at different spatial scales and over different correlated variables. Spatial change of support is a key inferential problem in these applications and have become…
Magnetic resonance imaging (MRI) plays a vital role in the scientific investigation and clinical management of multiple sclerosis. Analyses of binary multiple sclerosis lesion maps are typically "mass univariate" and conducted with standard…
In many applications, survey data are collected from different survey centers in different regions. It happens that in some circumstances, response variables are completely observed while the covariates have missing values. In this paper,…
Joint models for longitudinal and survival data have become a popular framework for studying the association between repeatedly measured biomarkers and clinical events. Nevertheless, addressing complex survival data structures, especially…
In modern spatial statistics, the structure of data that is collected has become more heterogeneous. Depending on the type of spatial data, different modeling strategies for spatial data are used. For example, a kriging approach for…
The reuse of medico-administrative and synthetic spatial data may overcome some limitations of population-based registries, provided rigorous validation is performed. However, no tool exists to spatially validate a candidate-for-reuse…
Modeling and recognition of surgical activities poses an interesting research problem. Although a number of recent works studied automatic recognition of surgical activities, generalizability of these works across different tasks and…
In cancer research, overall survival and progression free survival are often analyzed with the Cox model. To estimate accurately the parameters in the model, sufficient data and, more importantly, sufficient events need to be observed. In…
Environmental and climate processes are often distributed over large space-time domains. Their complexity and the amount of available data make modelling and analysis a challenging task. Statistical modelling of environment and climate data…
Due to spatial dependence -- often characterized as complex and non-linear -- model misspecification is a prevalent and critical issue in spatial data analysis and prediction. As the data, and thus model performance, is heterogeneous,…
This paper presents two case studies of data sets where the main inferential goal is to characterize time-varying patterns in model structure. Both of these examples are seen to be general cases of the so-called "partition problem," where…
Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…
In recent years, medical information technology has made it possible for electronic health record (EHR) to store fairly complete clinical data. This has brought health care into the era of "big data". However, medical data are often sparse…
Nonstationary non-Gaussian spatial data are common in many disciplines, including climate science, ecology, epidemiology, and social sciences. Examples include count data on disease incidence and binary satellite data on cloud mask…
This paper introduces TimeDepFrail, an R package designed to implement time-varying shared frailty models by extending the traditional shared frailty Cox model to allow the frailty term to evolve across time intervals. These models are…
Detecting spatial patterns is fundamental to scientific discovery, yet current methods lack statistical consensus and face computational barriers when applied to large-scale spatial omics datasets. We unify major approaches through a single…