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We introduce the so called DeepParticle method to learn and generate invariant measures of stochastic dynamical systems with physical parameters based on data computed from an interacting particle method (IPM). We utilize the expressiveness…

Machine Learning · Computer Science 2022-06-22 Zhongjian Wang , Jack Xin , Zhiwen Zhang

The Keller-Segel (KS) chemotaxis system is used to describe the overall behavior of a collection of cells under the influence of chemotaxis. However, solving the KS chemotaxis system and generating its aggregation patterns remain…

Numerical Analysis · Mathematics 2025-10-17 Yani Feng , Michael K. Ng , Zhiwen Zhang

This paper aims to efficiently compute transport maps between probability distributions arising from particle representation of bio-physical problems. We develop a bidirectional DeepParticle (BDP) method to learn and generate solutions…

Computational Physics · Physics 2025-04-17 Tan Zhang , Zhongjian Wang , Jack Xin , Zhiwen Zhang

Chemotaxis models describe the movement of organisms in response to chemical gradients. In this paper, we present a stochastic interacting particle-field algorithm with a random batch approximation (SIPF-$r$) for the three-dimensional (3D)…

Numerical Analysis · Mathematics 2026-01-26 Boyi Hu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

We introduce an efficient stochastic interacting particle-field (SIPF) algorithm with no history dependence for computing aggregation patterns and near singular solutions of parabolic-parabolic Keller-Segel (KS) chemotaxis system in three…

Numerical Analysis · Mathematics 2025-01-22 Zhongjian Wang , Jack Xin , Zhiwen Zhang

We consider the Keller-Segel model of chemotaxis on one-dimensional networks. Using a variational characterization of solutions, positivity preservation, conservation of mass, and energy estimates, we establish global existence of weak…

Numerical Analysis · Mathematics 2018-05-03 Herbert Egger , Lucas Schöbel-Kröhn

The Keller--Segel PDE is a model for chemotaxis known to exhibit possible finite-time blow-up. Following a seminal work by Tello and Winkler, a logistic damping term is added in this PDE and local well-posedness of mild solutions is proven.…

Probability · Mathematics 2025-12-24 Thomas Cavallazzi , Alexandre Richard , Milica Tomasevic

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

Analysis of PDEs · Mathematics 2013-02-20 Ibrahim Fatkullin

In this work, we develop a novel numerical scheme to solve the classical Keller--Segel (KS) model which simultaneously preserves its intrinsic mathematical structure and achieves optimal accuracy. The model is reformulated into a gradient…

Numerical Analysis · Mathematics 2025-09-23 X. Yin , X. Lan , Y. Qin

This paper is concerned with numerical approximation of some two-dimensional Keller-Segel chemotaxis models, especially those generating pattern formations. The numerical resolution of such nonlinear parabolic-parabolic or…

Numerical Analysis · Mathematics 2020-10-29 M. Benzakour Amine

We study fast and reliable generative transport for the 3D KS (Keller-Segel) and KPP (Kolmogorov-Petrovsky-Piskunov) equations in the presence of fluid flows with the goal to approximate the map between initial and terminal distributions…

Computational Physics · Physics 2026-01-29 Zhenda Shen , Zhongjian Wang , Jack Xin , Zhiwen Zhang

Chemotaxis systems play a crucial role in modeling the dynamics of bacterial and cellular behaviors, including propagation, aggregation, and pattern formation, all under the influence of chemical signals. One notable characteristic of these…

Numerical Analysis · Mathematics 2024-02-07 Alina Chertock , Shumo Cui , Alexander Kurganov , Chenxi Wang

In this paper, we propose and study a stochastic aggregation-diffusion equation of the Keller-Segel (KS) type for modeling the chemotaxis in dimensions $d=2,3$. Unlike the classical deterministic KS system, which only allows for…

Analysis of PDEs · Mathematics 2020-09-23 Hui Huang , Jinniao Qiu

In this paper, we develop a novel numerical framework, namely the stochastic interacting particle-field method with particle-in-cell acceleration (SIPF-PIC), for the efficient simulation of the three-dimensional (3D) parabolic-parabolic…

Numerical Analysis · Mathematics 2026-02-11 Jingyuan Hu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

We propose a unified learning framework for identifying the profile function in discrete Keller-Segel equations, which are widely used mathematical models for understanding chemotaxis. Training data are obtained via either a rigorously…

Numerical Analysis · Mathematics 2025-10-28 Chi-An Chen , Chun Liu , Ming Zhong

We use adversarial network architectures together with the Wasserstein distance to generate or refine simulated detector data. The data reflect two-dimensional projections of spatially distributed signal patterns with a broad spectrum of…

Instrumentation and Methods for Astrophysics · Physics 2018-02-12 Martin Erdmann , Lukas Geiger , Jonas Glombitza , David Schmidt

Tumor angiogenesis involves a collection of tumor cells moving towards blood vessels for nutrients to grow. Angiogenesis, and in general chemotaxis systems have been modeled using partial differential equations (PDEs) and as such require…

Numerical Analysis · Mathematics 2026-04-20 Jongwon David Kim , Jack Xin

The Keller-Segel partial differential equation is a two-dimensional model for chemotaxis. When the total mass of the initial density is one, it is known to exhibit blow-up in finite time as soon as the sensitivity $\chi$ of bacteria to the…

Probability · Mathematics 2015-07-07 Nicolas Fournier , Benjamin Jourdain

In this work we propose a deep adaptive sampling (DAS) method for solving partial differential equations (PDEs), where deep neural networks are utilized to approximate the solutions of PDEs and deep generative models are employed to…

Numerical Analysis · Mathematics 2022-07-06 Kejun Tang , Xiaoliang Wan , Chao Yang

This paper introduces a deep learning-based super-resolution (SR) framework specifically developed for accurately reconstructing high-resolution velocity fields in two-way coupled particle-laden turbulent flows. Leveraging conditional…

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