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Biofilm growth and transport in confined systems frequently occur in natural and engineered systems. Designing customizable engineered porous materials for controllable biofilm transportation properties could significantly improve the rapid…

Biological Physics · Physics 2023-10-10 Hanfeng Zhai , Jingjie Yeo

Inspired by the natural defence strategies of insect wings and plant leaves, nanostructured surfaces have emerged as a promising tool in various fields, including engineering, biomedical sciences, and materials science to combat bacterial…

Biological Physics · Physics 2025-03-04 Vladimir A. Baulin , Denver P. Linklater , Saulius Juodkazis , Elena P. Ivanova

We introduce a Bayesian optimization approach to guide the sputter deposition of molybdenum thin films, aiming to achieve desired residual stress and sheet resistance while minimizing susceptibility to stochastic fluctuations during…

Materials Science · Physics 2024-05-07 Ankit Shrivastava , Matias Kalaswad , Joyce O. Custer , David P. Adams , Habib N. Najm

Biofilms are bacterial aggregates encased in a self-produced polymeric matrix which attach to moist surfaces and are extremely resistant to chemicals and antibiotics. Recent experiments show that their structure is defined by the interplay…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian , Perfecto Vidal

Biofilms are a cluster of bacteria embedded in extracellular polymeric substances (EPS) that contain a complex composition of polysaccharides, proteins, and extracellular DNA (eDNA). Desirable mechanical properties of the biofilms are…

Applied Physics · Physics 2019-01-15 Enrique A. López-Guerra , Hongchen Shen , Santiago D. Solares , Danmeng Shuai

A stochastic model is used to assess the effect of external parameters on the development of submerged biofilms on smooth and rough surfaces. The model includes basic cellular mechanisms, such as division and spreading, together with an…

Soft Condensed Matter · Physics 2024-01-17 David Rodriguez , Baldvin Einarsson , Ana Carpio

High Power Targetry (HPT) R&D is critical in the context of increasing beam intensity and energy for next generation accelerators. Many target concepts and novel materials are being developed and tested for their ability to withstand…

Accelerator Physics · Physics 2024-06-04 W. Asztalos , Y. Torun , S. Bidhar , F. Pellemoine , P. Rath

From multicellular tissues to bacterial colonies, three dimensional cellular structures arise through the interaction of cellular activities and mechanical forces. Simple bacterial communities provide model systems for analyzing such…

Soft Condensed Matter · Physics 2024-01-11 Ana Carpio , Elena Cebrian , David R. Espeso , Perfecto Vidal

In the pursuit of designing safer and more efficient energy-absorbing structures, engineers must tackle the challenge of improving crush performance while balancing multiple conflicting objectives, such as maximising energy absorption and…

Materials Science · Physics 2025-02-25 Hirak Kansara , Siamak F. Khosroshahi , Leo Guo , Miguel A. Bessa , Wei Tan

With the emergence of new photonic and plasmonic materials with optimized properties as well as advanced nanofabrication techniques, nanophotonic devices are now capable of providing solutions to global challenges in energy conversion,…

This work presents a mathematical model for the optimal control of thin-film flows over a flexible topography influenced by an external force. Our thin-film model allows for the rupture of films as well as the coalescence of bubbles. The…

Optimization and Control · Mathematics 2025-06-19 S. Alrashidy , A. Kalogirou , D. Kalise , K. G. van der Zee

In many biological materials such as nacre and bone, the material structure consists of hard grains and soft interfaces, with the interfaces playing a significant role in the material's mechanical behavior. This type of structures has been…

Materials Science · Physics 2024-12-19 Wei Zhang , Mingjian Tang , Haoxuan Mu , Xingzi Yang , Xiaowei Zeng , Rui Tuo , Wei , Chen , Wei Gao

Biofilms are complex, self-organized consortia of microorganisms that produce a functional, protective matrix of biomolecules. Physically, the structure of a biofilm can be described as an entangled polymer network which grows and changes…

Biological Physics · Physics 2016-11-08 Marco G. Mazza

Biofilms are communities of bacteria that exhibit a multitude of multiscale biomechanical behaviors. Recent experimental advances have lead to characterizations of these behaviors in terms of measurements of the viscoelastic moduli of…

Cell Behavior · Quantitative Biology 2017-07-19 Jay A. Stotsky , Vanja Dukic , David M. Bortz

Controlling the properties of organic/inorganic materials requires detailed knowledge of their molecular adsorption geometries. This is often unattainable, even with current state-of-the-art tools. Visualizing the structure of complex…

Finding the optimal design of a hydrodynamic or aerodynamic surface is often impossible due to the expense of evaluating the cost functions (say, with computational fluid dynamics) needed to determine the performances of the flows that the…

Computational Geometry · Computer Science 2022-11-15 Haris Moazam Sheikh , Tess A. Callan , Kealan J. Hennessy , Philip S. Marcus

The sessile microbial communities known as biofilms exhibit varying architectures as environmental factors are varied, which for immersed biofilms includes the shear rate of the surrounding flow. Here we modify an established agent-based…

Biological Physics · Physics 2014-03-11 D. A. Head

To solve large-scale or high-resolution topology optimization problem, a novel algorithm is developed based on modified bi-directional evolutionary structure optimization (BESO) and extended finite element method (XFEM). Within XFEM, a set…

Applied Physics · Physics 2026-04-07 Hongxin Wang , Jie Liu , Guilin Wen

Bacteria often develop distinct phenotypes to adapt to environmental stress. In particular, they can produce biofilms, dense communities of bacteria that live in a complex extracellular matrix. Bacterial biofilms provide a safe haven from…

Quantitative Methods · Quantitative Biology 2025-08-29 Stephen Williams , Daravuth Cheam , Michele K. Nishiguchi , Suzanne S. Sindi , Shilpa Khatri , Erica M. Rutter

Topology optimization is able to maximally leverage the high DOFs and mechanical potentiality of porous foams but faces three fundamental challenges: conforming to free-form outer shapes, maintaining geometric connectivity between adjacent…

Graphics · Computer Science 2023-08-09 Ming Li , Jingqiao Hu , Wei Chen , Weipeng Kong , Jin Huang
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