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Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Medical Physics · Physics 2020-05-21 Dufan Wu , Hui Ren , Quanzheng Li

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Deep learning (DL) methods have been extensively applied to various image recovery problems, including magnetic resonance imaging (MRI) and computed tomography (CT) reconstruction. Beyond supervised models, other approaches have been…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Shijun Liang , Ismail Alkhouri , Qing Qu , Rongrong Wang , Saiprasad Ravishankar

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

Deep image prior (DIP) serves as a good inductive bias for diverse inverse problems. Among them, denoising is known to be particularly challenging for the DIP due to noise fitting with the requirement of an early stopping. To address the…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Yeonsik Jo , Se Young Chun , Jonghyun Choi

Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired…

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Ti Bai , Biling Wang , Dan Nguyen , Bao Wang , Bin Dong , Wenxiang Cong , Mannudeep K. Kalra , Steve Jiang

Low-dose computed tomography (CT) denoising algorithms aim to enable reduced patient dose in routine CT acquisitions while maintaining high image quality. Recently, deep learning~(DL)-based methods were introduced, outperforming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-21 Fabian Wagner , Mareike Thies , Felix Denzinger , Mingxuan Gu , Mayank Patwari , Stefan Ploner , Noah Maul , Laura Pfaff , Yixing Huang , Andreas Maier

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Denoising of clinical CT images is an active area for deep learning research. Current clinically approved methods use iterative reconstruction methods to reduce the noise in CT images. Iterative reconstruction techniques require multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

Reconstructing images using Computed Tomography (CT) in an industrial context leads to specific challenges that differ from those encountered in other areas, such as clinical CT. Indeed, non-destructive testing with industrial CT will often…

Image and Video Processing · Electrical Eng. & Systems 2024-12-02 Emilien Valat , Andreas Hauptmann , Ozan Öktem

Deep image prior (DIP) is an unsupervised deep learning framework that has been successfully applied to a variety of inverse imaging problems. However, DIP-based methods are inherently prone to overfitting, which leads to performance…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Panagiotis Gkotsis , Athanasios A. Rontogiannis

We present a comprehensive overview of the Deep Image Prior (DIP) framework and its applications to image reconstruction in computed tomography. Unlike conventional deep learning methods that rely on large, supervised datasets, the DIP…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Simon Arridge , Riccardo Barbano , Alexander Denker , Zeljko Kereta

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is widely used to evaluate acute ischemic stroke to distinguish salvageable tissue and infarct core. For this purpose, traditional methods employ deconvolution techniques,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Anbo Cao , Pin-Yu Le , Zhonghui Qie , Haseeb Hassan , Yingwei Guo , Asim Zaman , Jiaxi Lu , Xueqiang Zeng , Huihui Yang , Xiaoqiang Miao , Taiyu Han , Guangtao Huang , Yan Kang , Yu Luo , Jia Guo

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier
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