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We show that the mean field equations for the SIR epidemic can be exactly solved for a network with arbitrary degree distribution. Our exact solution consists of reducing the dynamics to a lone first order differential equation, which has a…

Physics and Society · Physics 2012-06-28 Andrew Lucas

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

Physics and Society · Physics 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

The role of waning immunity in basic epidemic models on networks has been undervalued while being noticeable fundamental for real epidemic outbreaks. One central question is which mean-field approach is more accurate in describing the…

Physics and Society · Physics 2022-10-05 José Carlos M. Silva , Diogo H. Silva , Francisco A. Rodrigues , Silvio C. Ferreira

Here we propose and implement a generalized mathematical model to find the time evolution of population in infectious diseases and apply the model to study the recent COVID-19 pandemic. Our model at the core is a non-local generalization of…

Populations and Evolution · Quantitative Biology 2020-05-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

Optimization and Control · Mathematics 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

In this paper we model the role of a government of a large population as a mean field optimal control problem. Such control problems are constrainted by a PDE of continuity-type, governing the dynamics of the probability distribution of the…

Optimization and Control · Mathematics 2016-08-08 Giacomo Albi , Young-Pil Choi , Massimo Fornasier , Dante Kalise

We present a quenched mean-field (QMF) theory for the dynamics of the susceptible-infected-susceptible (SIS) epidemic model on complex networks where dynamical correlations between connected vertices are taken into account by means of a…

Biological Physics · Physics 2013-09-11 Angélica S. Mata , Silvio C. Ferreira

We have developed a globally applicable diagnostic Covid-19 model by augmenting the classical SIR epidemiological model with a neural network module. Our model does not rely upon previous epidemics like SARS/MERS and all parameters are…

Physics and Society · Physics 2020-11-24 Raj Dandekar , Chris Rackauckas , George Barbastathis

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

We consider the problem of representing collective behavior of large populations and predicting the evolution of a population distribution over a discrete state space. A discrete time mean field game (MFG) is motivated as an interpretable…

Machine Learning · Computer Science 2018-04-24 Jiachen Yang , Xiaojing Ye , Rakshit Trivedi , Huan Xu , Hongyuan Zha

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

A broad class of systems, including ecological, epidemiological, and sociological ones, are characterized by populations of individuals assigned to specific categories, e.g., a chemical species, an opinion or an epidemic state, that are…

Statistical Mechanics · Physics 2025-07-17 Giorgio Vittorio Visco , Johannes Nauta , Tomas Scagliarini , Oriol Artime , Manlio De Domenico

We propose a model predictive control (MPC) approach for minimising the social distancing and quarantine measures during a pandemic while maintaining a hard infection cap. To this end, we study the admissible and the maximal robust…

Optimization and Control · Mathematics 2022-05-05 Philipp Sauerteig , Willem Esterhuizen , Mitsuru Wilson , Tobias K. S. Ritschel , Karl Worthmann , Stefan Streif

The COronaVIrus Disease 2019 (COVID-19) pandemic that has had the world in its grip from the beginning of 2020, has resulted in an unprecedented level of public interest and media attention on the field of mathematical epidemiology. Ever…

Other Quantitative Biology · Quantitative Biology 2022-03-25 Sitabhra Sinha

A generalization of the standard susceptible-infectious-removed (SIR) stochastic model for epidemics in sparse random networks is introduced which incorporates contact tracing in addition to random screening. We propose a deterministic…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Ramon Huerta , Lev S. Tsimring

Motivated by the classical Susceptible-Infected-Recovered (SIR) epidemic models proposed by Kermack and Mckendrick, we consider a class of stochastic compartmental dynamical systems with a notion of partial ordering among the compartments.…

Populations and Evolution · Quantitative Biology 2019-01-03 Wasiur R. KhudaBukhsh , Boseung Choi , Eben Kenah , Grzegorz A. Rempala

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

This review presents and reviews various solved and open problems in developing, analyzing, and mitigating epidemic spreading processes under human decision-making. We provide a review of a range of epidemic models and explain the pros and…

Systems and Control · Electrical Eng. & Systems 2021-12-10 Yunhan Huang , Quanyan Zhu

While most existing epidemic models focus on the influence of isolated factors, infectious disease transmission is inherently shaped by the complex interplay of multiple interacting elements. To better capture real-world dynamics, it is…

Physics and Society · Physics 2025-04-18 Guangyuan Mei , Yao Cai , Su-Su Zhang , Ying Huang , Chuang Liu , Xiu-Xiu Zhan