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During the past decade, interest has grown significantly in developing ultrasensitive widefield diamond magnetometry for various applications. Despite attempts to improve the adoption of conventional frame-based sensors, achieving high…

Instrumentation and Detectors · Physics 2023-06-27 Zhiyuan Du , Madhav Gupta , Feng Xu , Kai Zhang , Jiahua Zhang , Yan Zhou , Yiyao Liu , Zhenyu Wang , Jorg Wrachtrup , Ngai Wong , Can Li , Zhiqin Chu

High biocompatibility, variable size ranging from ~ 5 nm, stable luminescence from its color centers and simple carbon chemistry for biomolecule grafting make nanodiamond (ND) particles an attractive alternative to molecular dyes for…

The integration of light and materials technology is key to the creation of innovative sensing technologies. Sensing of electric and magnetic fields, and temperature with high spatio-temporal resolution is a critical task for the…

The nitrogen-vacancy (NV) center is a potential atomic-scale spin sensor for electric field sensing. However, its natural susceptibility to the magnetic field hinders effective detection of the electric field. Here we propose a robust…

The glow of a starry night sky, the smell of a freshly brewed cup of coffee or the sound of ocean waves breaking on the beach are representations of the physical world that have been created by the dynamic interactions of thousands of…

Neurons and Cognition · Quantitative Biology 2011-07-28 Henry Lütcke , Fritjof Helmchen

Magnetocardiography (MCG) has emerged as a sensitive and precise method to diagnose cardiovascular diseases, providing more diagnostic information than traditional technology. However, the sensor limitations of conventional MCG systems,…

Medical Physics · Physics 2024-05-07 Ziyun Yu , Yijin Xie , Guodong Jin , Yunbin Zhu , Qi Zhang , Fazhan Shi , Fang-yan Wan , Hongmei Luo , Ai-hui Tang , Xing Rong

We present a method of optical magnetometry with parts-per-billion resolution that is able to detect biomagnetic signals generated from the human brain and heart in Earth's ambient environment. Our magnetically silent sensors measure the…

Medical Physics · Physics 2020-07-29 M. E. Limes , E. L. Foley , T. W. Kornack , S. Caliga , S. McBride , A. Braun , W. Lee , V. G. Lucivero , M. V. Romalis

Nitrogen-vacancy (NV) center in diamond is a promising quantum sensor with remarkably versatile sensing capabilities. While scanning NV magnetometry is well-established, NV electrometry has been so far limited to bulk diamonds. Here we…

Quantum Physics · Physics 2022-10-12 Ziwei Qiu , Assaf Hamo , Uri Vool , Tony X. Zhou , Amir Yacoby

Quantum sensing utilizes quantum systems as sensors to capture weak signal, and provides new opportunities in nowadays science and technology. The strongest adversary in quantum sensing is decoherence due to the coupling between the sensor…

Quantum Physics · Physics 2020-07-15 Yijin Xie , Jianpei Geng , Huiyao Yu , Xing Rong , Ya Wang , Jiangfeng Du

Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…

Quantum sensors based on nitrogen-vacancy centers in diamond have emerged as a promising detection modality for nuclear magnetic resonance (NMR) spectroscopy owing to their micron-scale detection volume and non-inductive based detection. A…

Nitrogen-vacancy (NV) centers in diamond can be used as quantum sensors to image the magnetic field with nanoscale resolution. However, nanoscale electric-field mapping has not been achieved so far because of the relatively weak coupling…

Mesoscale and Nanoscale Physics · Physics 2021-05-04 Ke Bian , Wentian Zheng , Xianzhe Zeng , Xiakun Chen , Rainer Stohr , Andrej Denisenko , Sen Yang , Joerg Wrachtrup , Ying Jiang

We report progress toward a CMOS-integrated quantum diamond biosensing platform that combines nitrogen-vacancy (NV) centers in diamond with a custom 40 nm CMOS Single-Photon Avalanche Diode (SPAD) array. The system integrates on-chip active…

A key challenge in cardiology is the non-invasive imaging of electric current propagation occurring in the cardiovascular system at an intra-cardiac scale. A promising approach for directly mapping the current dynamics is to monitor the…

Noise-induced control imperfection is an important problem in applications of diamond-based nano-scale sensing, where measurement-based strategies are generally utilized to correct low-frequency noises in realtime. However, the spin-state…

Quantum Physics · Physics 2023-03-31 Nanyang Xu , Feifei Zhou , Xiangyu Ye , Xue Lin , Bao Chen , Ting Zhang , Feng Yue , Bing Chen , Ya Wang , Jiangfeng Du

Nitrogen-vacancy (NV) based quantum sensors hold great potential for real-time single-cell sensing with far-reaching applications in fundamental biology and medical diagnostics. Although highly sensitive, the mapping of quantum measurements…

Magnetic fields generated by human and animal organs, such as the heart, brain and nervous system carry information useful for biological and medical purposes. These magnetic fields are most commonly detected using cryogenically-cooled…

Charge control of color centers in semiconductors promises opportunities for novel forms of sensing and quantum information processing. Here, we articulate confocal fluorescence microscopy and magnetic resonance protocols to induce and…

Quantum sensing with nitrogen-vacancy (NV) centers in diamond promises to revolutionize biological research and medical diagnostics. Thanks to their high sensitivity, NV sensors could, in principle, detect specific binding events with…

Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely new approaches may be required, motivating an analysis…