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Molecular dynamics (MD) simulations play a crucial role in resolving the underlying conformational dynamics of molecular systems. However, their capability to correctly reproduce and predict dynamics in agreement with experiments is limited…

Chemical Physics · Physics 2025-05-19 Ivan Gilardoni , Valerio Piomponi , Thorben Fröhlking , Giovanni Bussi

Deep learning has achieved great success in a wide spectrum of multimedia applications such as image classification, natural language processing and multimodal data analysis. Recent years have seen the development of many deep learning…

Machine Learning · Computer Science 2021-08-06 Naili Xing , Sai Ho Yeung , Chenghao Cai , Teck Khim Ng , Wei Wang , Kaiyuan Yang , Nan Yang , Meihui Zhang , Gang Chen , Beng Chin Ooi

We introduce a general-purpose framework for interconnecting scientific simulation programs using a homogeneous, unified software interface. Our framework is intrinsically parallel, and conveniently separates all components in memory. It…

Astrophysics of Galaxies · Physics 2011-10-14 Simon Portegies Zwart , Stephen McMillan , Inti Pelupessy , Arjen van Elteren

A desire to achieve large medical imaging datasets keeps increasing as machine learning algorithms, parallel computing, and hardware technology evolve. Accordingly, there is a growing demand in pooling data from multiple clinical and…

Image and Video Processing · Electrical Eng. & Systems 2021-12-06 Yukai Zou , Ikbeom Jang

Applications that require substantial computational resources today cannot avoid the use of heavily parallel machines. Embracing the opportunities of parallel computing and especially the possibilities provided by a new generation of…

Computational Physics · Physics 2017-09-14 Martin Weigel

Quantum Mechanics/Molecular Mechanics (QM/MM) simulations are a popular approach to study various features of large systems. A common application of QM/MM calculations is in the investigation of reaction mechanisms in condensed-phase and…

Chemical Physics · Physics 2020-10-29 Jorge Nochebuena , Sehr Naseem-Khan , G. Andrés Cisneros

Numerical investigation of compressible flows faces two main challenges. In order to accurately describe the flow characteristics, high-resolution nonlinear numerical schemes are needed to capture discontinuities and resolve wide…

Computational Physics · Physics 2020-12-09 Nils Hoppe , Stefan Adami , Nikolaus A. Adams

Precision Medicine (PM) is an emerging approach that appears with the impression of changing the existing paradigm of medical practice. Recent advances in technological innovations and genetics, and the growing availability of health data…

Computers and Society · Computer Science 2019-11-05 Muhammad Afzal , S. M. Riazul Islam , Maqbool Hussain , Sungyoung Lee

Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations. Ensemble-based simulations are used widely to compute a number of individual…

Computational Engineering, Finance, and Science · Computer Science 2020-09-14 Vivek Balasubramanian , Travis Jensen , Matteo Turilli , Peter Kasson , Michael Shirts , Shantenu Jha

Recently, both industry and academia have proposed several different neuromorphic systems to execute machine learning applications that are designed using Spiking Neural Networks (SNNs). With the growing complexity on design and technology…

Neural and Evolutionary Computing · Computer Science 2022-02-21 Phu Khanh Huynh , M. Lakshmi Varshika , Ankita Paul , Murat Isik , Adarsha Balaji , Anup Das

As systems become more complex, the demand for thorough testing and virtual prototyping grows. To simulate whole systems, multiple tools are usually needed to cover different parts. These parts include the hardware of a system and the…

Software Engineering · Computer Science 2025-10-28 Nils Bosbach , Meik Schmidt , Lukas Jünger , Matthias Berthold , Rainer Leupers

Many researchers have criticized the field of Software Complexity metrics for the lack of testing, verification, and reproducibility of many metrics and case studies that utilized those metrics. This document describes SMF, a tool that can…

Software Engineering · Computer Science 2017-11-20 Charles Hathaway

The reproduction and replication of novel results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the issues closely revolve around the…

Software Engineering · Computer Science 2014-09-17 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

The simulation of the behavior of the human brain is one of the most ambitious challenges today with a non-end of important applications. We can find many different initiatives in the USA, Europe and Japan which attempt to achieve such a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-14 Pedro Valero-Lara , Raül Sirvent , Antonio J. Peña , Jesús Labarta

The theory of spin models intersects with condensed matter physics, complex systems, graph theory, combinatorial optimization, computational complexity and neural networks. Many ensuing applications rely on the fact that complicated spin…

Mathematical Physics · Physics 2024-08-02 Tobias Reinhart , Benjamin Engel , Gemma De les Coves

Programming Language Processing (PLP) using machine learning has made vast improvements in the past few years. Increasingly more people are interested in exploring this promising field. However, it is challenging for new researchers and…

Machine Learning · Computer Science 2023-06-19 Patrick Flynn , Tristan Vanderbruggen , Chunhua Liao , Pei-Hung Lin , Murali Emani , Xipeng Shen

Designing a robotic system that functions effectively within the specific environment of a Magnetic Resonance Imaging (MRI) scanner requires solving numerous technical issues, such as maintaining the robot's precision and stability under…

Robotics · Computer Science 2026-01-06 Wenhui Chu , Aobo Jin , Hardik A. Gohel

Machine learning (ML) provides a broad spectrum of tools and architectures that enable the transformation of data from simulations and experiments into useful and explainable science, thereby augmenting domain knowledge. Furthermore,…

Plasma Physics · Physics 2024-09-05 Farbod Faraji , Maryam Reza

Interpretability for machine learning models in medical imaging (MLMI) is an important direction of research. However, there is a general sense of murkiness in what interpretability means. Why does the need for interpretability in MLMI…

Machine Learning · Computer Science 2024-04-17 Alan Q. Wang , Batuhan K. Karaman , Heejong Kim , Jacob Rosenthal , Rachit Saluja , Sean I. Young , Mert R. Sabuncu

Recently, learning methods have been designed to create Multiplane Images (MPIs) for view synthesis. While MPIs are extremely powerful and facilitate high quality renderings, a great amount of memory is required, making them impractical for…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Julia Navarro , Neus Sabater