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The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Accurate segmentation of anatomical structures is vital for medical image analysis. The state-of-the-art accuracy is typically achieved by supervised learning methods, where gathering the requisite expert-labeled image annotations in a…

Computer Vision and Pattern Recognition · Computer Science 2020-12-04 Yuhang Lu , Kang Zheng , Weijian Li , Yirui Wang , Adam P. Harrison , Chihung Lin , Song Wang , Jing Xiao , Le Lu , Chang-Fu Kuo , Shun Miao

Shortened Abstract Cone-beam computed tomography (CBCT) has become a widely adopted modality for image-guided radiotherapy (IGRT). However, CBCT suffers from increased noise, limited soft-tissue contrast, and artifacts, resulting in…

Medical Physics · Physics 2025-06-11 Ciro Benito Raggio , Paolo Zaffino , Maria Francesca Spadea

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Objective: Dynamic cone-beam CT (CBCT) imaging is highly desired in image-guided radiation therapy to provide volumetric images with high spatial and temporal resolutions to enable applications including tumor motion tracking/prediction and…

Medical Physics · Physics 2023-02-22 You Zhang , Tielige Mengke

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang

Deformable multi-contrast image registration is a challenging yet crucial task due to the complex, non-linear intensity relationships across different imaging contrasts. Conventional registration methods typically rely on iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Yinsong Wang , Xinzhe Luo , Siyi Du , Chen Qin

Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-30 Zhe Zhu , Michael Harowicz , Jun Zhang , Ashirbani Saha , Lars J. Grimm , E. Shelley Hwang , Maciej A. Mazurowski

Clinicians compare breast DCE-MRI after neoadjuvant chemotherapy (NAC) with pre-treatment scans to evaluate the response to NAC. Clinical evidence supports that accurate longitudinal deformable registration without deforming treated tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Luyi Han , Tao Tan , Tianyu Zhang , Yuan Gao , Xin Wang , Valentina Longo , Sofía Ventura-Díaz , Anna D'Angelo , Jonas Teuwen , Ritse Mann

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

Although developed functional magnetic resonance imaging (fMRI) registration algorithms based on deep learning have achieved a certain degree of alignment of functional area, they underutilized fine structural information. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Baolong Li , Yuhu Shi , Lei Wang , Weiming Zeng , Changming Zhu

This paper presents a predictive model for estimating regularization parameters of diffeomorphic image registration. We introduce a novel framework that automatically determines the parameters controlling the smoothness of diffeomorphic…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Jian Wang , Miaomiao Zhang

Modelling the physical properties of everyday objects is a fundamental prerequisite for autonomous robots. We present a novel generative adversarial network (Defo-Net), able to predict body deformations under external forces from a single…

Robotics · Computer Science 2018-04-18 Zhihua Wang , Stefano Rosa , Linhai Xie , Bo Yang , Sen Wang , Niki Trigoni , Andrew Markham

Affine registration plays a crucial role in PET/CT imaging, where aligning PET with CT images is challenging due to their respective functional and anatomical representations. Despite the significant promise shown by recent deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Junyu Chen , Yihao Liu , Shuwen Wei , Aaron Carass , Yong Du

Deformable image registration (DIR) is a crucial and challenging technique for aligning anatomical structures in medical images and is widely applied in diverse clinical applications. However, existing approaches often struggle to capture…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Shayan Kebriti , Shahabedin Nabavi , Ali Gooya

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

We present Deep Shape-from-Template (DeepSfT), a novel Deep Neural Network (DNN) method for solving real-time automatic registration and 3D reconstruction of a deformable object viewed in a single monocular image.DeepSfT advances the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 David Fuentes-Jimenez , David Casillas-Perez , Daniel Pizarro , Toby Collins , Adrien Bartoli

Generalizability is a concern when applying a deep learning (DL) model trained on one dataset to other datasets. Training a universal model that works anywhere, anytime, for anybody is unrealistic. In this work, we demonstrate the…

Medical Physics · Physics 2020-04-20 Xiao Liang , Dan Nguyen , Steve Jiang