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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

The recent success of brain-inspired deep neural networks (DNNs) in solving complex, high-level visual tasks has led to rising expectations for their potential to match the human visual system. However, DNNs exhibit idiosyncrasies that…

Neurons and Cognition · Quantitative Biology 2019-05-08 Chihye Han , Wonjun Yoon , Gihyun Kwon , Seungkyu Nam , Daeshik Kim

Deep Neural Networks in NLP have enabled systems to learn complex non-linear relationships. One of the major bottlenecks towards being able to use DNNs for real world applications is their characterization as black boxes. To solve this…

Computation and Language · Computer Science 2022-06-01 Subhadip Maji , Arijit Ghosh Chowdhury , Raghav Bali , Vamsi M Bhandaru

Deep neural networks (DNNs) may outperform human brains in complex tasks, but the lack of transparency in their decision-making processes makes us question whether we could fully trust DNNs with high stakes problems. As DNNs' operations…

Machine Learning · Computer Science 2020-03-19 Jung Hoon Lee

Predictions obtained by, e.g., artificial neural networks have a high accuracy but humans often perceive the models as black boxes. Insights about the decision making are mostly opaque for humans. Particularly understanding the decision…

Machine Learning · Computer Science 2021-01-21 Nadia Burkart , Marco F. Huber

In recent years, the use of sophisticated statistical models that influence decisions in domains of high societal relevance is on the rise. Although these models can often bring substantial improvements in the accuracy and efficiency of…

Machine Learning · Computer Science 2021-04-13 Alfredo Carrillo , Luis F. Cantú , Alejandro Noriega

Recent technological advancements have led to a large number of patents in a diverse range of domains, making it challenging for human experts to analyze and manage. State-of-the-art methods for multi-label patent classification rely on…

Artificial Intelligence · Computer Science 2024-07-30 Md Shajalal , Sebastian Denef , Md. Rezaul Karim , Alexander Boden , Gunnar Stevens

Deep Neural Networks (DNNs) have been extensively used in many areas including image processing, medical diagnostics, and autonomous driving. However, DNNs can exhibit erroneous behaviours that may lead to critical errors, especially when…

Software Engineering · Computer Science 2023-04-21 Zohreh Aghababaeyan , Manel Abdellatif , Lionel Briand , Ramesh S , Mojtaba Bagherzadeh

Black box machine learning models are currently being used for high stakes decision-making throughout society, causing problems throughout healthcare, criminal justice, and in other domains. People have hoped that creating methods for…

Machine Learning · Statistics 2019-09-24 Cynthia Rudin

While deep learning models have demonstrated remarkable success in numerous domains, their black-box nature remains a significant limitation, especially in critical fields such as medical image analysis and inference. Existing…

Machine Learning · Computer Science 2025-05-13 David Zucker

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin

Deep neural networks are widely used for classification. These deep models often suffer from a lack of interpretability -- they are particularly difficult to understand because of their non-linear nature. As a result, neural networks are…

Artificial Intelligence · Computer Science 2017-11-22 Oscar Li , Hao Liu , Chaofan Chen , Cynthia Rudin

Along with the great success of deep neural networks, there is also growing concern about their black-box nature. The interpretability issue affects people's trust on deep learning systems. It is also related to many ethical problems, e.g.,…

Machine Learning · Computer Science 2022-02-01 Yu Zhang , Peter Tiňo , Aleš Leonardis , Ke Tang

Deep neural networks (DNNs) are famous for their high prediction accuracy, but they are also known for their black-box nature and poor interpretability. We consider the problem of variable selection, that is, selecting the input variables…

Machine Learning · Statistics 2019-09-18 Zixuan Song , Jun Li

This study compares various superlearner and deep learning architectures (machine-learning-based and neural-network-based) for classification problems across several simulated and industrial datasets to assess performance and computational…

Machine Learning · Statistics 2017-08-23 Colleen M. Farrelly

Deep Neural Networks (DNNs) are often considered black boxes due to their opaque decision-making processes. To reduce their opacity Concept Models (CMs), such as Concept Bottleneck Models (CBMs), were introduced to predict human-defined…

Human-Computer Interaction · Computer Science 2025-12-02 Jack Furby , Dan Cunnington , Dave Braines , Alun Preece

In recent years, deep neural networks have showcased their predictive power across a variety of tasks. Beyond natural language processing, the transformer architecture has proven efficient in addressing tabular data problems and challenges…

Machine Learning · Computer Science 2025-04-14 Anton Thielmann , Arik Reuter , Benjamin Saefken

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu

In recent years, machine learning (ML) has become a key enabling technology for the sciences and industry. Especially through improvements in methodology, the availability of large databases and increased computational power, today's ML…

Artificial Intelligence · Computer Science 2019-09-27 Wojciech Samek , Klaus-Robert Müller

Recent advancements in signal processing and machine learning domains have resulted in an extensive surge of interest in deep learning models due to their unprecedented performance and high accuracy for different and challenging problems of…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Atefeh Shahroudnejad , Arash Mohammadi , Konstantinos N. Plataniotis