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This paper is motivated by the recent interest in the analysis of high dimen- sional microbiome data. A key feature of this data is the presence of `structural zeros' which are microbes missing from an observation vector due to an…

Applications · Statistics 2016-05-23 Abhishek Kaul , Ori Davidov , Shyamal D. Peddada

Compositional data are met in many different fields, such as economics, archaeometry, ecology, geology and political sciences. Regression where the dependent variable is a composition is usually carried out via a log-ratio transformation of…

Methodology · Statistics 2017-06-08 Michail Tsagris , Connie Stewart

Regression analysis with compositional data containing zero values

Methodology · Statistics 2015-08-11 Michail Tsagris

This paper introduces a rectified and renormalized Fisher-Bingham model for compositional data with zeros, motivated in part by the presence of zeros in microbiota studies. The approach represents compositions through a square-root…

Methodology · Statistics 2026-04-29 Eugene Han , Marahi Perez-Tamayo , Hannah D. Holscher , Ruoqing Zhu

In real world applications dealing with compositional datasets, it is easy to face the presence of structural zeros. The latter arise when, due to physical limitations, one or more variables are intrinsically zero for a subset of the…

Methodology · Statistics 2025-10-28 Francesco Porro , Fabio Rapallo , Sara Sommariva

This paper proposes a new generalized linear model with the fractional binomial distribution. Zero-inflated Poisson/negative binomial distributions are used for count data with many zeros. To analyze the association of such a count variable…

Methodology · Statistics 2025-08-01 Jeonghwa Lee , Chloe Breece

In this work we show a Bayesian quantile regression method to response variables with mixed discrete-continuous distribution with a point mass at zero, where these observations are believed to be left censored or true zeros. We combine the…

Methodology · Statistics 2015-11-19 Bruno Santos , Heleno Bolfarine

The paper proposes a novel model assessment paradigm aiming to address shortcoming of posterior predictive $p-$values, which provide the default metric of fit for Bayesian structural equation modelling (BSEM). The model framework of the…

Methodology · Statistics 2022-06-30 Konstantinos Vamvourellis , Konstantinos Kalogeropoulos , Irini Moustaki

We introduce a self-censoring model for multivariate nonignorable nonmonotone missing data, where the missingness process of each outcome is affected by its own value and is associated with missingness indicators of other outcomes, while…

Methodology · Statistics 2022-10-03 Yilin Li , Wang Miao , Ilya Shpitser , Eric J. Tchetgen Tchetgen

Several approaches have been proposed in the literature for clustering multivariate ordinal data. These methods typically treat missing values as absent information, rather than recognizing them as valuable for profiling population…

Methodology · Statistics 2024-11-05 Alice Giampino , Antonio Canale , Bernardo Nipoti

In compositional data, an observation is a vector with non-negative components which sum to a constant, typically 1. Data of this type arise in many areas, such as geology, archaeology, biology, economics and political science amongst…

Methodology · Statistics 2015-11-25 Michail Tsagris

Statistical analysis on compositional data has gained a lot of attention due to their great potential of applications. A feature of these data is that they are multivariate vectors that lie in the simplex, that is, the components of each…

In compositional data, an observation is a vector with non-negative components which sum to a constant, typically 1. Data of this type arise in many areas, such as geology, archaeology, biology, economics and political science among others.…

Methodology · Statistics 2015-06-18 Michail Tsagris

Zero-inflated continuous data ubiquitously appear in many fields, in which lots of exactly zero-valued data are observed while others distribute continuously. Due to the mixed structure of discreteness and continuity in its distribution,…

Methodology · Statistics 2024-10-28 Keita Hamamoto

This paper describes a compound Poisson-based random effects structure for modeling zero-inflated data. Data with large proportion of zeros are found in many fields of applied statistics, for example in ecology when trying to model and…

Applications · Statistics 2009-07-29 Marie-Pierre Etienne , Eric Parent , Benoit Hugues , Bernier Jacques

The growing use of high-throughput sequencing (HTS) has enabled the large-scale production of compositional count data, driving progress in microbiome research. However, such count data are often high-dimensional, over-dispersed, and…

Other Statistics · Statistics 2026-05-22 Wenqi Tang , Kamila Fačevicová , Klaus Nordhausen , Sara Taskinen

We study a high-dimensional regression setting under the assumption of known covariate distribution. We aim at estimating the amount of explained variation in the response by the best linear function of the covariates (the signal level). In…

Statistics Theory · Mathematics 2022-05-12 Ilan Livne , David Azriel , Yair Goldberg

The human microbiome can contribute to pathogeneses of many complex diseases by mediating disease-leading causal pathways. However, standard mediation analysis methods are not adequate to analyze the microbiome as a mediator due to the…

People easily recognize new visual categories that are new combinations of known components. This compositional generalization capacity is critical for learning in real-world domains like vision and language because the long tail of new…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Yuval Atzmon , Felix Kreuk , Uri Shalit , Gal Chechik

Many data sets cannot be accurately described by standard probability distributions due to the excess number of zero values present. For example, zero-inflation is prevalent in microbiome data and single-cell RNA sequencing data, which…

Methodology · Statistics 2024-11-20 Max Beveridge , Zach Goldstein , Hee Cheol Chung
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