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Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new…

Molecular Networks · Quantitative Biology 2026-05-26 Kyle R. Allison

In the brain, coherent neuronal activities often appear simultaneously in multiple frequency bands, e.g., as combinations of alpha (8-12 Hz), beta (12.5-30 Hz), gamma (30-120 Hz) oscillations, among others. These rhythms are believed to…

Neurons and Cognition · Quantitative Biology 2023-04-26 Tianyi Wu , Yuhang Cai , Ruilin Zhang , Zhongyi Wang , Louis Tao , Zhuo-Cheng Xiao

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

This paper describes a relatively simple way of allowing a brain model to self-organise its concept patterns through nested structures. Time is a key element and a simulator would be able to show how patterns may form and then fire in…

Neural and Evolutionary Computing · Computer Science 2014-09-05 Kieran Greer

Cognitive function requires the coordination of neural activity across many scales, from neurons and circuits to large-scale networks. As such, it is unlikely that an explanatory framework focused upon any single scale will yield a…

Neurons and Cognition · Quantitative Biology 2018-01-19 Luca Cocchi , Leonardo L. Gollo , Andrew Zalesky , Michael Breakspear

A rigorous understanding of brain dynamics and function requires a conceptual bridge between multiple levels of organization, including neural spiking and network-level population activity. Mounting evidence suggests that neural networks of…

Neurons and Cognition · Quantitative Biology 2016-10-11 Yahya Karimipanah , Zhengyu Ma , Ralf Wessel

Networks of model neurons with balanced recurrent excitation and inhibition produce irregular and asynchronous spiking activity. We extend the analysis of balanced networks to include the known dependence of connection probability on the…

Neurons and Cognition · Quantitative Biology 2014-06-02 Robert Rosenbaum , Brent Doiron

Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

Biological Physics · Physics 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

In the last two decades, network science has blossomed and influenced various fields, such as statistical physics, computer science, biology and sociology, from the perspective of the heterogeneous interaction patterns of components…

Physics and Society · Physics 2021-04-20 Ming Li , Run-Ran Liu , Linyuan Lü , Mao-Bin Hu , Shuqi Xu , Yi-Cheng Zhang

The seemingly stochastic transient dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference. In vitro neurons, on the other hand, exhibit a highly deterministic…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Grid cells in the medial entorhinal cortex (MEC) respond when an animal occupies a periodic lattice of "grid fields" in the environment. The grids are organized in modules with spatial periods, or scales, clustered around discrete values…

Neurons and Cognition · Quantitative Biology 2019-03-13 Louis Kang , Vijay Balasubramanian

This work is part of an effort to understand the neural basis for our visual system's ability, or failure, to accurately track moving visual signals. We consider here a ring model of spiking neurons, intended as a simplified computational…

Neurons and Cognition · Quantitative Biology 2016-01-13 Guillaume Lajoie , Lai-Sang Young

Diffusion is a fundamental phenomenon that occurs ubiquitously in nature and remains the subject of continuous research interest. Understanding diffusion is a key to understanding leaving systems. In this Chapter, I discuss diffusion of…

Soft Condensed Matter · Physics 2018-10-15 Svyatoslav Kondrat

Signal propagation over long distances is a ubiquitous feature of multicellular communities. In biofilms of the bacterium Bacillus subtilis, we recently discovered that some, but not all, cells participate in the propagation of an…

Biological Physics · Physics 2020-07-01 Xiaoling Zhai , Joseph W. Larkin , Kaito Kikuchi , Samuel E. Redford , Gürol M. Süel , Andrew Mugler

Hippocampal place and time cells encode spatial and temporal aspects of experience. Both have the same neural substrate, but have been modeled as having different functions and mechanistic origins, place cells as continuous attractors, and…

Neurons and Cognition · Quantitative Biology 2026-04-02 Qiaorong S. Yu , Zhaoze Wang , Vijay Balasubramanian

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Communicating cells can coordinate their gene expressions to form spatial patterns. 'Secrete-and-sense cells' secrete and sense the same molecule to do so and are ubiquitous. Here we address why and how these cells, from disordered…

Quantitative Methods · Quantitative Biology 2018-06-05 Eduardo P. Olimpio , Yiteng Dang , Hyun Youk

Working memory is responsible for the temporary manipulation and storage of information to support reasoning, learning and comprehension in the human brain. Background oscillations from subcortical structures may drive a gating or switching…

Neurons and Cognition · Quantitative Biology 2016-01-29 Utku Çelikok , Eva M. Navarro-López , Neslihan S. Şengör

The hippocampus is often attributed to episodic memory formation and storage in the mammalian brain; in particular, Alme et al. showed that hippocampal area CA3 forms statistically independent representations across a large number of…

Neurons and Cognition · Quantitative Biology 2021-01-01 Bhav Jain , Sean Elliott
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