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Shortcut engineering consists of a class of approaches to rapidly manipulate physical systems by means of specially designed external controls. In this Letter, we apply these approaches to run-and-tumble particles, which are designed to…

Statistical Mechanics · Physics 2023-04-13 Adam G. Frim , Michael R. DeWeese

Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,…

Fluid Dynamics · Physics 2023-11-09 Brato Chakrabarti , Stanislav Y. Shvartsman , Michael J. Shelley

Taking inspiration from the crawling motion of biological cells on a substrate, we consider a physical model of self-propulsion where the spatio-temporal driving can involve both, a mechanical actuation by active force couples, and a…

Soft Condensed Matter · Physics 2024-05-16 Pierre Recho , Lev Truskinovsky

Perimeter control maintains high traffic efficiency within protected regions by controlling transfer flows among regions to ensure that their traffic densities are below critical values. Existing approaches can be categorized as either…

Machine Learning · Computer Science 2023-06-01 Xiaocan Li , Ray Coden Mercurius , Ayal Taitler , Xiaoyu Wang , Mohammad Noaeen , Scott Sanner , Baher Abdulhai

The manipulation of a collection of fluid particles in a low Reynolds number environment has several important applications. As we demonstrate in this paper, this manipulation problem is related to the scientific question of how fluid flow…

Fluid Dynamics · Physics 2024-02-27 Jake Buzhardt , Phanindra Tallapragada

Simulations are vital for understanding and predicting the evolution of complex molecular systems. However, despite advances in algorithms and special purpose hardware, accessing the timescales necessary to capture the structural evolution…

Computational Physics · Physics 2021-02-18 Pantelis R. Vlachas , Julija Zavadlav , Matej Praprotnik , Petros Koumoutsakos

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

Active networks made of biopolymers and motor proteins are valuable bioinspired systems that have been used in the last decades to study the cytoskeleton and its self-organization under mechanical stimulation. Different techniques are…

Soft Condensed Matter · Physics 2023-05-15 Vahid Nasirimarekani , Olinka Ramìrez-Soto , Stefan Karpitschka , Isabella Guido

In a prototypical mode of single-cell migration, retrograde cytoskeletal flow is mechanically coupled to the environment, propels the cell, and is sustained by an anterograde cytosolic flow of disassembled cytoskeletal components.…

Biological Physics · Physics 2024-03-19 Jordi Font-Reverter , Alejandro Torres-Sánchez , Guillermo Vilanova , Marino Arroyo

The movement of ionic solutions is an essential part of biology and technology. Fluidics, from nano- to micro- to microfluidics, is a burgeoning area of technology which is all about the movement of ionic solutions, on various scales. Many…

Quantitative Methods · Quantitative Biology 2018-06-08 Shixin Xu , Bob Eisenberg , Zilong Song , Huaxiong Huang

Active fluid droplets surrounded by oil can spontaneously develop circulatory flows. However, the dynamics of the surrounding oil and their influence on the active fluid remain poorly understood. To investigate interactions between the…

Fluid Dynamics · Physics 2021-05-27 Yen-Chen Chen , Brock Jolicoeur , Chih-Che Chueh , Kun-Ta Wu

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

Soft Condensed Matter · Physics 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

Controlling fluidic flows in active droplets is crucial in developing intelligent models to understand and mimic single-celled microorganisms. Typically, these fluidic flows are affected by the interfacial dynamics of chemical agents. We…

Soft Condensed Matter · Physics 2024-05-10 Muhammad Turab Ali Khan , Gaurav Gardi , Ren Hao Soon , Mingchao Zhang , Metin Sitti

Stochastic Spatio-Temporal processes are prevalent across domains ranging from modeling of plasma to the turbulence in fluids to the wave function of quantum systems. This letter studies a measure-theoretic description of such systems by…

Optimization and Control · Mathematics 2021-05-25 George I. Boutselis , Ethan N. Evans , Marcus A. Pereira , Evangelos A. Theodorou

Living systems continuously sense, integrate, and act on chemical information using multiscale biochemical networks whose dynamics are inherently nonlinear, adaptive, and energy-efficient. Yet, most attempts to harness such "wetware" for…

Emerging Technologies · Computer Science 2026-02-03 Ceylin Savas , Maryam Javed , Murat Kuscu

Living systems are made of active materials with microscopic components that work together to perform macroscopic biological tasks. The breakdown of these collective functionalities leads to diseases, which, conversely, could be treated by…

Data obtained from Flow Cytometry present pronounced variability due to biological and technical reasons. Biological variability is a well-known phenomenon produced by measurements on different individuals, with different characteristics…

Computational fluid dynamics (CFD) provides high-fidelity simulations of fluid flows but remains computationally expensive for many-query applications. In recent years deep learning (DL) has been used to construct data-driven fluid-dynamic…

Machine Learning · Computer Science 2026-04-13 David Ramos , Lucas Lacasa , Fermín Gutiérrez , Eusebio Valero , Gonzalo Rubio

Time-variant systems have recently garnered considerable attention due to their unique potentials in manipulating electromagnetic waves. Here, a novel class of topological spacetime crystals is introduced, with a traveling-wave modulation…

Optics · Physics 2025-09-24 João C. Serra , Mário G. Silveirinha

Active particles, including swimming microorganisms, autophoretic colloids and droplets, are known to self-organize into ordered structures at fluid-solid boundaries. The entrainment of particles in the attractive parts of their spontaneous…

Soft Condensed Matter · Physics 2018-07-04 Shashi Thutupalli , Delphine Geyer , Rajesh Singh , Ronojoy Adhikari , Howard Stone
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