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Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and…

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Qingchao Zhang , Coy D. Heldermon , Corey Toler-Franklin

Automatic segmentation of retina vessels plays a pivotal role in clinical diagnosis of prevalent eye diseases, such as, Diabetic Retinopathy or Age-related Macular Degeneration. Due to the complex construction of blood vessels, with…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Benjamin Hou

Hand-crafted features extracted from dynamic contrast-enhanced magnetic resonance images (DCE-MRIs) have shown strong predictive abilities in characterization of breast lesions. However, heterogeneity across medical image datasets hinders…

Medical Physics · Physics 2017-01-17 Natalia Antropova , Benjamin Huynh , Maryellen Giger

A brain tumour is a mass or cluster of abnormal cells in the brain, which has the possibility of becoming life-threatening because of its ability to invade neighbouring tissues and also form metastases. An accurate diagnosis is essential…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Soumick Chatterjee , Faraz Ahmed Nizamani , Andreas Nürnberger , Oliver Speck

Accurate, noninvasive glioma characterization is crucial for effective clinical management. Traditional methods, dependent on invasive tissue sampling, often fail to capture the spatial heterogeneity of the tumor. While deep learning has…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Somayeh Farahani , Marjaneh Hejazi , Antonio Di Ieva , Emad Fatemizadeh , Sidong Liu

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

Lung and colon cancers are predominant contributors to cancer mortality. Early and accurate diagnosis is crucial for effective treatment. By utilizing imaging technology in different image detection, learning models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Diponkor Bala , S M Rakib Ul Karim , Rownak Ara Rasul

This work presents a mitosis detection method with only one vanilla Convolutional Neural Network (CNN). Our method consists of two steps: given an image, we first apply a CNN using a sliding window technique to extract patches that have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Hongyan Gu , Mohammad Haeri , Shuo Ni , Christopher Kazu Williams , Neda Zarrin-Khameh , Shino Magaki , Xiang 'Anthony' Chen

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Image and Video Processing · Electrical Eng. & Systems 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Qifei Cui , Xinyu Lu

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

Melanoma is a type of cancer that begins in the cells controlling the pigment of the skin, and it is often referred to as the most dangerous skin cancer. Diagnosing melanoma can be time-consuming, and a recent increase in melanoma incidents…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Marie Bø-Sande , Edvin Benjaminsen , Neel Kanwal , Saul Fuster , Helga Hardardottir , Ingrid Lundal , Emiel A. M. Janssen , Kjersti Engan

Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Marc Aubreville , Jonathan Ganz , Jonas Ammeling , Taryn A. Donovan , Rutger H. J. Fick , Katharina Breininger , Christof A. Bertram

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Martin Weigert , Uwe Schmidt , Wenhua Zhang , Jun Zhang , Sen Yang , Jinxi Xiang , Xiyue Wang , Josef Lorenz Rumberger , Elias Baumann , Peter Hirsch , Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Ayushi Jain , Heeyoung Ahn , Yiyu Hong , Hussam Azzuni , Min Xu , Mohammad Yaqub , Marie-Claire Blache , Benoît Piégu , Bertrand Vernay , Tim Scherr , Moritz Böhland , Katharina Löffler , Jiachen Li , Weiqin Ying , Chixin Wang , Dagmar Kainmueller , Carola-Bibiane Schönlieb , Shuolin Liu , Dhairya Talsania , Yughender Meda , Prakash Mishra , Muhammad Ridzuan , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Banban Huang , Hsiang-Chin Chien , Ching-Ping Wang , Chia-Yen Lee , Hong-Kun Lin , Zaiyi Liu , Xipeng Pan , Chu Han , Jijun Cheng , Muhammad Dawood , Srijay Deshpande , Raja Muhammad Saad Bashir , Adam Shephard , Pedro Costa , João D. Nunes , Aurélio Campilho , Jaime S. Cardoso , Hrishikesh P S , Densen Puthussery , Devika R G , Jiji C , Ye Zhang , Zijie Fang , Zhifan Lin , Yongbing Zhang , Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Vi Thi-Tuong Vo , Soo-Hyung Kim , Taebum Lee , Satoshi Kondo , Satoshi Kasai , Pranay Dumbhare , Vedant Phuse , Yash Dubey , Ankush Jamthikar , Trinh Thi Le Vuong , Jin Tae Kwak , Dorsa Ziaei , Hyun Jung , Tianyi Miao , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir M. Rajpoot

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier
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