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The progression of breast cancer can be quantified in lymph node whole-slide images (WSIs). We describe a novel method for effectively performing classification of whole-slide images and patient level breast cancer grading. Our method…

Computer Vision and Pattern Recognition · Computer Science 2017-07-25 Thomas Wollmann , Karl Rohr

Automatic detection and segmentation of cells and nuclei in microscopy images is important for many biological applications. Recent successful learning-based approaches include per-pixel cell segmentation with subsequent pixel grouping, or…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Uwe Schmidt , Martin Weigert , Coleman Broaddus , Gene Myers

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by…

Computer Vision and Pattern Recognition · Computer Science 2014-06-30 Erik Cuevas , Margarita Diaz , Miguel Manzanares , Daniel Zaldivar , Marco Perez

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Brain tumor classification using MRI images is critical in medical diagnostics, where early and accurate detection significantly impacts patient outcomes. While recent advancements in deep learning (DL), particularly CNNs, have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Priyam Ganguly , Akhilbaran Ghosh

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

In this work, we address the challenge of binary lung nodule classification (benign vs malignant) using CT images by proposing a multi-level attention stacked ensemble of deep neural networks. Three pretrained backbones -- EfficientNet V2…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Uzzal Saha , Surya Prakash

Breast cancer (BC) remains a significant health threat, with no long-term cure currently available. Early detection is crucial, yet mammography interpretation is hindered by high false positives and negatives. With BC incidence projected to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Jai Vardhan , Taraka Satya Krishna Teja Malisetti

Currently, the computational complexity limits the training of high resolution gigapixel images using Convolutional Neural Networks. Therefore, such images are divided into patches or tiles. Since, these high resolution patches are encoded…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Suvidha Tripathi , Satish Kumar Singh , Lee Hwee Kuan

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Encoding whole slide images (WSI) as graphs is well motivated since it makes it possible for the gigapixel resolution WSI to be represented in its entirety for the purpose of graph learning. To this end, WSIs can be broken into smaller…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Milan Aryal , Nasim Yahyasoltani

This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Natnael Alemayehu

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

In digital pathology, cell detection and classification are often prerequisites to quantify cell abundance and explore tissue spatial heterogeneity. However, these tasks are particularly challenging for multiplex immunohistochemistry (mIHC)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Yeman Brhane Hagos , Priya Lakshmi Narayanan , Ayse U. Akarca , Teresa Marafioti , Yinyin Yuan

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Automated white blood cell (WBC) classification is essential for leukemia screening but remains challenged by extreme class imbalance, long-tail distributions, and domain shift, leading deep models to overfit dominant classes and fail on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Duc T. Nguyen , Hoang-Long Nguyen , Huy-Hieu Pham

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Lucas Sancéré , Noémie Moreau , Katarzyna Bozek

Brain tumor detection and classification are critical tasks in medical image analysis, particularly in early-stage diagnosis, where accurate and timely detection can significantly improve treatment outcomes. In this study, we apply various…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Alice Oh , Inyoung Noh , Jian Choo , Jihoo Lee , Justin Park , Kate Hwang , Sanghyeon Kim , Soo Min Oh

A definitive diagnosis of a brain tumour is essential for enhancing treatment success and patient survival. However, it is difficult to manually evaluate multiple magnetic resonance imaging (MRI) images generated in a clinic. Therefore,…

Neural and Evolutionary Computing · Computer Science 2022-04-27 Amin Abdollahi Dehkordi , Mina Hashemi , Mehdi Neshat , Seyedali Mirjalili , Ali Safaa Sadiq