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Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

While Fourier ptychography (FP) offers super-resolution for macroscopic imaging, its real-world application is severely hampered by atmospheric turbulence, a challenge largely unaddressed in existing macroscopic FP research operating under…

Information about microscopic objects with features smaller than the diffraction limit is almost entirely lost in a far-field diffraction image but could be partly recovered with data completition techniques. Any such approach critically…

Optics · Physics 2020-11-17 Maria Bancerek , Krzysztof M. Czajkowski , Rafal Kotynski

We propose Frequency-Guided Attention (FGA), a lightweight upsampling module for single image super-resolution. Conventional upsamplers, such as Sub-Pixel Convolution, are efficient but frequently fail to reconstruct high-frequency details…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Daejune Choi , Youchan No , Jinhyung Lee , Duksu Kim

Learning-based image super-resolution aims to reconstruct high-frequency (HF) details from the prior model trained by a set of high- and low-resolution image patches. In this paper, HF to be estimated is considered as a combination of two…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Jian Zhang , Chen Zhao , Ruiqin Xiong , Siwei Ma , Debin Zhao

Image blur and image noise are imaging artifacts intrinsically arising in image acquisition. In this paper, we consider multi-frame blind deconvolution (MFBD), where image blur is described by the convolution of an unobservable,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Leonid Kostrykin , Stefan Harmeling

Fourier ptychographic microscopy (FPM) is a pivotal computational imaging technique that achieves phase and amplitude reconstruction with high resolution and wide field of view, using low numerical aperture objectives and LED array…

We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

In example-based super-resolution, the function relating low-resolution images to their high-resolution counterparts is learned from a given dataset. This data-driven approach to solving the inverse problem of increasing image resolution…

Image and Video Processing · Electrical Eng. & Systems 2018-12-05 Alexander Robey , Vidya Ganapati

We study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function (PSF) of a…

Light field cameras have been proved to be powerful tools for 3D reconstruction and virtual reality applications. However, the limited resolution of light field images brings a lot of difficulties for further information display and…

Image and Video Processing · Electrical Eng. & Systems 2020-08-27 Qingyan Sun , Shuo Zhang , Song Chang , Lixi Zhu , Youfang Lin

Lensless cameras based on thin diffusers offer a compact alternative to conventional refractive imaging but rely on computational reconstruction, since the diffuser's point spread function (PSF) globally multiplexes every scene point across…

Optics · Physics 2026-04-20 Kerem Ekec , Uğur Teğin

The most ubiquitous form of computational aberration correction for microscopy is deconvolution. However, deconvolution relies on the assumption that the point spread function is the same across the entire field-of-view. This assumption is…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Amit Kohli , Anastasios N. Angelopoulos , David McAllister , Esther Whang , Sixian You , Kyrollos Yanny , Federico M. Gasparoli , Bo-Jui Chang , Reto Fiolka , Laura Waller

A phase retrieval technique using a spatial light modulator (SLM) and a phase diffuser for a fast reconstruction of smooth wave fronts is demonstrated experimentally. Diffuse illumination of a smooth test object with the aid of a phase…

Optics · Physics 2015-06-11 Mostafa Agour , Percival F. Almoro , Claas Falldorf

Due to image blurring image deconvolution is often used for studying biological structures in fluorescence microscopy. Fluorescence microscopy image volumes inherently suffer from intensity inhomogeneity, blur, and are corrupted by various…

Computer Vision and Pattern Recognition · Computer Science 2019-07-15 Soonam Lee , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Super-resolution is the process of obtaining a high-resolution image from one or more low-resolution images. Single image super-resolution (SISR) and multi-frame super-resolution (MFSR) methods have been evolved almost independently for…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Mohammad Mahdi Afrasiabi , Reshad Hosseini , Aliazam Abbasfar

Shape from Focus (SFF) is a depth reconstruction technique that estimates scene structure from focus variations observed across a focal stack, that is, a sequence of images captured at different focus settings. A key limitation of SFF…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Khurram Ashfaq , Muhammad Tariq Mahmood

Since 2014, the LBT's First Light Adaptive Optics (FLAO) system has also included a seldom used capability, known as Enhanced Seeing Mode (ESM), that can improve the angular resolution over a 4' x 4' field of view (FOV). In full AO…

Instrumentation and Methods for Astrophysics · Physics 2019-11-05 Barry Rothberg , Julian C. Christou , Douglas L. Miller , Dave Thompson , Gregory E. Taylor , Christian Veillet

Transient Photoluminescence Microscopy (TPLM) allows for the direct visualization of carrier transport in semiconductor materials with sub nanosecond and few nanometer resolution. The technique is based on measuring changes in the spatial…

Federated learning (FL) based magnetic resonance (MR) image reconstruction can facilitate learning valuable priors from multi-site institutions without violating patient's privacy for accelerating MR imaging. However, existing methods rely…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Juan Zou , Cheng Li , Ruoyou Wu , Tingrui Pei , Hairong Zheng , Shanshan Wang