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The goal of privacy metrics is to measure the degree of privacy enjoyed by users in a system and the amount of protection offered by privacy-enhancing technologies. In this way, privacy metrics contribute to improving user privacy in the…

Cryptography and Security · Computer Science 2018-06-21 Isabel Wagner , David Eckhoff

In the past decade, Genome-Wide Association Studies (GWAS) have delivered an increasingly broad view of the genetic basis of human phenotypic variation. One of the major developments from GWAS is polygenic scores, a genetic predictor of an…

Genomics · Quantitative Biology 2019-09-04 Graham Coop

Genetic data collection has become ubiquitous, producing genetic information about health, ancestry, and social traits. However, unregulated use, especially amid evolving scientific understanding, poses serious privacy and discrimination…

Computers and Society · Computer Science 2025-06-03 Vivek Ramanan , Ria Vinod , Cole Williams , Sohini Ramachandran , Suresh Venkatasubramanian

Polygenic risk scores (PRS) developed from genome-wide association studies (GWAS) can be used for risk stratification by quantifying the genetic contribution to disease, and many clinical applications have been proposed. Bayesian methods…

Methodology · Statistics 2026-03-11 Yuzheng Dun , Nilanjan Chatterjee , Jin Jin , Akihiko Nishimura

Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological…

Applications · Statistics 2017-07-21 Emilie Devijver , Mélina Gallopin , Emeline Perthame

This work proposes a novel privacy-preserving neural network feature representation to suppress the sensitive information of a learned space while maintaining the utility of the data. The new international regulation for personal data…

Computer Vision and Pattern Recognition · Computer Science 2020-08-10 Aythami Morales , Julian Fierrez , Ruben Vera-Rodriguez , Ruben Tolosana

Using real-world study data usually requires contractual agreements where research results may only be published in anonymized form. Requiring formal privacy guarantees, such as differential privacy, could be helpful for data-driven…

Cryptography and Security · Computer Science 2024-07-08 Jonas Allmann , Saskia Nuñez von Voigt , Florian Tschorsch

Differential privacy allows quantifying privacy loss resulting from accessing sensitive personal data. Repeated accesses to underlying data incur increasing loss. Releasing data as privacy-preserving synthetic data would avoid this…

Machine Learning · Statistics 2021-06-10 Joonas Jälkö , Eemil Lagerspetz , Jari Haukka , Sasu Tarkoma , Antti Honkela , Samuel Kaski

We study statistical risk minimization problems under a privacy model in which the data is kept confidential even from the learner. In this local privacy framework, we establish sharp upper and lower bounds on the convergence rates of…

Machine Learning · Statistics 2013-10-11 John C. Duchi , Michael I. Jordan , Martin J. Wainwright

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonzero effect on the trait. Evaluation of polygenicity can…

Genomics · Quantitative Biology 2022-07-26 Arunabha Majumdar , Bogdan Pasaniuc

A tremendous amount of individual-level data is generated each day, of use to marketing, decision makers, and machine learning applications. This data often contain private and sensitive information about individuals, which can be disclosed…

Cryptography and Security · Computer Science 2019-01-23 Marmar Orooji , Gerald M. Knapp

We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing…

Genomics · Quantitative Biology 2013-10-14 Yaniv Erlich , Arvind Narayanan

Software applications have become an omnipresent part of modern society. The consequent privacy policies of these applications play a significant role in informing customers how their personal information is collected, stored, and used.…

Cryptography and Security · Computer Science 2023-06-21 Shidong Pan , Thong Hoang , Dawen Zhang , Zhenchang Xing , Xiwei Xu , Qinghua Lu , Mark Staples

Statistical heterogeneity is a measure of how skewed the samples of a dataset are. It is a common problem in the study of differential privacy that the usage of a statistically heterogeneous dataset results in a significant loss of…

Machine Learning · Computer Science 2024-12-02 Mary Scott , Graham Cormode , Carsten Maple

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

Cryptography and Security · Computer Science 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

An increasing number of individuals are turning to Direct-To-Consumer (DTC) genetic testing to learn about their predisposition to diseases, traits, and/or ancestry. DTC companies like 23andme and Ancestry.com have started to offer popular…

Cryptography and Security · Computer Science 2016-11-11 Emiliano De Cristofaro , Kaitai Liang , Yuruo Zhang

Recent advances in score-based generative models have led to a huge spike in the development of downstream applications using generative models ranging from data augmentation over image and video generation to anomaly detection. Despite…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Mischa Dombrowski , Bernhard Kainz

Huge volume of data from domain specific applications such as medical, financial, telephone, shopping records and individuals are regularly generated. Sharing of these data is proved to be beneficial for data mining application. Since data…

Methodology · Statistics 2014-03-21 Hitesh Chhinkaniwala , Sanjay Garg

Recently introduced privacy legislation has aimed to restrict and control the amount of personal data published by companies and shared to third parties. Much of this real data is not only sensitive requiring anonymization, but also…

Databases · Computer Science 2020-07-20 Mostafa Milani , Yu Huang , Fei Chiang