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Functional protein-protein interactions are crucial in most cellular processes. They enable multi-protein complexes to assemble and to remain stable, and they allow signal transduction in various pathways. Functional interactions between…

Biomolecules · Quantitative Biology 2018-11-14 Anne-Florence Bitbol

One goal in the quantum-walk research is the exploitation of the intrinsic quantum nature of multiple walkers, in order to achieve the full computational power of the model. Here we study the behaviour of two non-interacting particles…

Quantum Physics · Physics 2016-02-26 Luca Rigovacca , Carlo Di Franco

We study numerically the behavior of continuous-time quantum walks over networks which are topologically equivalent to square lattices. On short time scales, when placing the initial excitation at a corner of the network, we observe a fast,…

Quantum Physics · Physics 2009-11-11 Oliver Muelken , Antonio Volta , Alexander Blumen

Given the extensive application of classical random walks to classical algorithms in a variety of fields, their quantum analogue in quantum walks is expected to provide a fruitful source of quantum algorithms. So far, however, such…

Quantum Physics · Physics 2008-03-26 B. L. Douglas , J. B. Wang

Protein-protein interaction networks provide a graph-level view of cellular organization, yet their functional modules are overlapping, noisy, and difficult to interpret from cluster assignments alone. Existing community-detection methods…

Social and Information Networks · Computer Science 2026-05-21 Sima Soltani , Mehrdad Jalali , Yahya Forghani

In the last twenty years network science has proven its strength in modelling many real-world interacting systems as generic agents, the nodes, connected by pairwise edges. Yet, in many relevant cases, interactions are not pairwise but…

Physics and Society · Physics 2020-02-26 Timoteo Carletti , Federico Battiston , Giulia Cencetti , Duccio Fanelli

Link prediction in complex networks has attracted increasing attention from both physical and computer science communities. The algorithms can be used to extract missing information, identify spurious interactions, evaluate network evolving…

Physics and Society · Physics 2015-05-20 Linyuan Lu , Tao Zhou

We employed the random graph theory approach to analyze the protein-protein interaction database DIP (Feb. 2004), for seven species (S. cerevisiae, H. pylori, E. coli, C. elegans, H. sapiens, M. musculus and D. melanogaster). Several global…

Molecular Networks · Quantitative Biology 2007-05-23 Ka-Lok Ng , Chien-Hung Huang

Quantum walks, the quantum mechanical counterpart of classical random walks, is an advanced tool for building quantum algorithms that has been recently shown to constitute a universal model of quantum computation. Quantum walks is now a…

Quantum Physics · Physics 2012-10-01 Salvador E. Venegas-Andraca

Many natural and artificial networks evolve in time. Nodes and connections appear and disappear at various timescales, and their dynamics has profound consequences for any processes in which they are involved. The first empirical analysis…

Statistical Mechanics · Physics 2012-05-21 Michele Starnini , Andrea Baronchelli , Alain Barrat , Romualdo Pastor-Satorras

Predictions of missing links of incomplete networks like protein-protein interaction networks or very likely but not yet existent links in evolutionary networks like friendship networks in web society can be considered as a guideline for…

Data Analysis, Statistics and Probability · Physics 2009-10-27 Linyuan Lv , Ci-Hang Jin , Tao Zhou

Identifying protein-protein interactions is crucial for a systems-level understanding of the cell. Recently, algorithms based on inverse statistical physics, e.g. Direct Coupling Analysis (DCA), have allowed to use evolutionarily related…

Biomolecules · Quantitative Biology 2020-03-25 Carlos A. Gandarilla-Pérez , Pierre Mergny , Martin Weigt , Anne-Florence Bitbol

Motivation: Protein-protein interactions (PPIs) are usually modelled as networks. These networks have extensively been studied using graphlets, small induced subgraphs capturing the local wiring patterns around nodes in networks. They…

Molecular Networks · Quantitative Biology 2018-04-13 Noel Malod-Dognin , Natasa Przulj

In this work, we present a new algorithm for generating quantum circuits that efficiently implement continuous time quantum walks on arbitrary simple sparse graphs. The algorithm, called matching decomposition, works by decomposing a…

Quantum Physics · Physics 2026-01-19 Mostafa Atallah , Alvin Gonzales , Daniel Dilley , Igor Gaidai , Zain H. Saleem , Rebekah Herrman

We study the classical and quantum transport processes on some finite networks and model them by continuous-time random walks (CTRW) and continuous-time quantum walks (CTQW), respectively. We calculate the classical and quantum transition…

Quantum Physics · Physics 2011-04-05 S. Salimi , R. Radgohar , M. M. Soltanzadeh

Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes…

Biomolecules · Quantitative Biology 2009-01-12 M. Weigt , R. A. White , H. Szurmant , J. A. Hoch , T. Hwa

Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in…

Biological Physics · Physics 2016-11-21 Anne-Florence Bitbol , Robert S. Dwyer , Lucy J. Colwell , Ned S. Wingreen

Stimulated by the growing interest in the applications of complex networks framework on time series analysis, we devise a network model in which each of $N$ nodes is associated with a random walk of length $L$. Connectivity between any two…

Physics and Society · Physics 2018-10-03 Harinder Pal , Thomas H. Seligman , Juan V. Escobar

The random walk process underlies the description of a large number of real world phenomena. Here we provide the study of random walk processes in time varying networks in the regime of time-scale mixing; i.e. when the network connectivity…

Networks have been used to model many real-world phenomena to better understand the phenomena and to guide experiments in order to predict their behavior. Since incorrect models lead to incorrect predictions, it is vital to have a correct…

Molecular Networks · Quantitative Biology 2007-05-23 Natasa Przulj , Derek G. Corneil , Igor Jurisica