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The objective of quantitative photoacoustic tomography (QPAT) is to reconstruct optical and thermodynamic properties of heterogeneous media from data of absorbed energy distribution inside the media. There have been extensive theoretical…

Medical Physics · Physics 2019-10-08 Alexander V. Mamonov , Kui Ren

In optoacoustic (photoacoustic) tomography, several parameters related to tissue and detector features are needed for image formation, but they may not be known a priori. An autofocus (AF) algorithm is generally used to estimate these…

Medical Physics · Physics 2022-03-14 Ludwig Englert , Lucas Riobo , Christine Schonemann , Vasilis Ntziachristos , Juan Aguirre

In the mathematical analysis of photoacoustic imaging, it is usually assumed that the acoustic pressure (Dirichlet data) is measured on a detection surface. However, actual ultrasound detectors gather data of a different type. In this…

Analysis of PDEs · Mathematics 2020-07-01 Sebastian Acosta

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Passive acoustic mapping (PAM) is a key imaging technique for characterizing cavitation activity in therapeutic ultrasound applications. Recent model-based beamforming algorithms offer high reconstruction quality and strong physical…

Image and Video Processing · Electrical Eng. & Systems 2026-01-13 Tatiana Gelvez-Barrera , Barbara Nicolas , Bruno Gilles , Adrian Basarab , Denis Kouamé

Image sensors are the backbone of many imaging technologies of great importance to modern sciences, being particularly relevant in biomedicine. An ideal image sensor should be usable through all the electromagnetic spectrum (large…

Medical Physics · Physics 2022-03-16 Juan Aguirre

Acoustic-resolution photoacoustic microscopy (AR-PAM) is a promising tool for microvascular imaging. In the focal region, resolution of AR-PAM is determined by the ultrasound transducer and ultimately limited by acoustic diffraction. In the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Fei Feng , Siqi Liang , Sung-Liang Chen

Photoacoustic tomography is a contrast agent-free imaging technique capable of visualizing blood vessels and tumor-associated vascularization in breast tissue. While sophisticated breast imaging systems have been recently developed, there…

Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Yuwei Zheng , Zijian Gao , Yuting Shen , Jiadong Zhang , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

In this paper, we describe the numerical reconstruction method for quantitative photoacoustic tomography (QPAT) based on the radiative transfer equation (RTE), which models light propagation more accurately than diffusion approximation…

Quantitative Methods · Quantitative Biology 2017-10-25 Chao Wang , Tie Zhou

In this article, we consider the inverse problem of determining spatially heterogeneous absorption and diffusion coefficients from a single measurement of the absorbed energy (in the steady-state diffusion approximation of light transfer).…

Analysis of PDEs · Mathematics 2015-10-09 Elena Beretta , Monika Muszkieta , Wolf Naetar , Otmar Scherzer

Quantum technologies that rely on photonic qubits require a precise controllability of their properties. For this purpose hybrid approaches are particularly attractive because they offer a large flexibility to address different aspects of…

We consider the mathematical model of photoacoustic and thermoacoustic tomography in media with a variable sound speed. When the sound speed is known, the explicit reconstruction formula by P. Stefanov and G. Uhlmann (Inverse Problems,…

Analysis of PDEs · Mathematics 2013-07-08 Lauri Oksanen , Gunther Uhlmann

Inspired by the recent advances on minimizing nonsmooth or bound-constrained convex functions on models using varying degrees of fidelity, we propose a line search multigrid (MG) method for full-wave iterative image reconstruction in…

Numerical Analysis · Mathematics 2016-11-22 Ashkan Javaherian , Sean Holman

In this paper we consider the inverse problem of vibro-acoustography, a technique for enhancing ultrasound imaging by making use of nonlinear effects. It amounts to determining two spatially variable coefficients in a system of PDEs…

Numerical Analysis · Mathematics 2023-03-31 Barbara Kaltenbacher ans teresa Rauscher

We derive an explicit method for reconstructing singularities of the initial data in a thermoacoustic tomography problem, in the case of variable sound speed and limited boundary data. In order to obtain this explicit formula we assume the…

Analysis of PDEs · Mathematics 2009-05-19 Dustin Steinhauer

Singular value decomposition is central to many problems in engineering and scientific fields. Several quantum algorithms have been proposed to determine the singular values and their associated singular vectors of a given matrix. Although…

Quantum Physics · Physics 2021-06-30 Xin Wang , Zhixin Song , Youle Wang

This paper concerns the quantitative step of the medical imaging modality Thermo-acoustic Tomography (TAT). We model the radiation propagation by a system of Maxwell's equations. We show that the index of refraction of light and the…

Analysis of PDEs · Mathematics 2015-06-17 Guillaume Bal , Ting Zhou

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

Optics · Physics 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar