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The traditional goal of inverse self-assembly is to design interactions that drive particles toward a desired target structure. However, achieving successful self-assembly also requires tuning the thermodynamic conditions under which the…

Soft Condensed Matter · Physics 2025-06-16 Camilla Beneduce , Giuseppe Mastriani , Petr Šulc , Francesco Sciortino , John Russo

Inverse design can be a useful strategy for discovering interactions that drive particles to spontaneously self-assemble into a desired structure. Here, we extend an inverse design methodology--relative entropy optimization--to determine…

Soft Condensed Matter · Physics 2018-03-16 William D. Piñeros , Beth A. Lindquist , Ryan B. Jadrich , Thomas M. Truskett

Isotropic pairwise interactions that promote the self assembly of complex particle morphologies have been discovered by inverse design strategies derived from the molecular coarse-graining literature. While such approaches provide an avenue…

Statistical Mechanics · Physics 2019-10-15 Beth A. Lindquist , Ryan B. Jadrich , Michael P. Howard , Thomas M. Truskett

While colloids are promising building blocks for the self-assembly of materials with novel microstructures, their numerous tunable parameters inhibit brute force searching for appropriate parameter combinations that yield self-assembly of a…

Soft Condensed Matter · Physics 2020-03-13 Beth A Lindquist

One emerging approach for the fabrication of complex architectures on the nanoscale is to utilize particles customized to intrinsically self-assemble into a desired structure. Inverse methods of statistical mechanics have proven…

Materials Science · Physics 2017-09-08 R. B. Jadrich , B. A. Lindquist , T. M. Truskett

We propose an optimisation method for the inverse structural design of self-assembly of anisotropic patchy particles. The anisotropic interaction can be expressed by the spherical harmonics of the surface pattern on a patchy particle, and…

Soft Condensed Matter · Physics 2025-02-21 Uyen Tu Lieu , Natsuhiko Yoshinaga

We propose a general framework for solving inverse self-assembly problems, i.e. designing interactions between elementary units such that they assemble spontaneously into a predetermined structure. Our approach uses patchy particles as…

Soft Condensed Matter · Physics 2022-07-13 John Russo , Flavio Romano , Lukas Kroc , Francesco Sciortino , Lorenzo Rovigatti , Petr Sulc

Multi-component self-assembly mixtures offer the possibility of encoding multiple target structures with the same set of interacting components. Selective retrieval of one of the stored structures has been attempted by preparing an initial…

Soft Condensed Matter · Physics 2022-03-23 Arunkumar Bupathy , Daan Frenkel , Srikanth Sastry

Throughout the physical sciences, entropy stands out as a pivotal but enigmatic concept that, in materials design, often takes a backseat to energy. Here, we demonstrate how to precisely engineer entropy to achieve desired colloidal…

Soft Condensed Matter · Physics 2019-07-23 Yina Geng , Greg van Anders , Paul M. Dodd , Julia Dshemuchadse , Sharon C. Glotzer

Curved structures in soft matter and biological systems commonly emerge as a result of self-assembly processes where building blocks aggregate in a controlled manner, giving rise to specific system structure and properties. Learning how to…

Soft Condensed Matter · Physics 2025-02-24 Andraž Gnidovec , Simon Čopar

Colloidal self-assembly -- the spontaneous organization of colloids into ordered structures -- has been considered key to produce next-generation materials. However, the present-day staggering variety of colloidal building blocks and the…

Soft Condensed Matter · Physics 2021-06-29 Gabriele Maria Coli , Emanuele Boattini , Laura Filion , Marjolein Dijkstra

Anisotropy at the level of the inter-particle interaction provides the particles with specific instructions for the self-assembly of target structures. The ability to synthesize non-spherical colloids, together with the possibility of…

Soft Condensed Matter · Physics 2020-01-03 Carina Karner , Christoph Dellago , Emanuela Bianchi

The synthesis of complex materials through the self-assembly of particles at the nanoscale provides opportunities for the realization of novel material properties. However, the inverse design process to create experimentally feasible…

Soft Condensed Matter · Physics 2022-03-01 Carl S. Adorf , James Antonaglia , Julia Dshemuchadse , Sharon C. Glotzer

We formulate statistical-mechanical inverse methods in order to determine optimized interparticle interactions that spontaneously produce target many-particle configurations. Motivated by advances that give experimentalists greater and…

Soft Condensed Matter · Physics 2007-05-23 Mikael C. Rechtsman , Salvatore Torquato , Frank H. Stillinger

In this paper we introduce a new method to design interparticle interactions to target arbitrary crystal structures via the process of self-assembly. We show that it is possible to exploit the curvature of the crystal nucleation free-energy…

Soft Condensed Matter · Physics 2010-12-21 William L. Miller , Angelo Cacciuto

Self-assembly is one of the prevalent strategies used by living systems to fabricate ensembles of precision nanometer-scale structures and devices. The push for analogous approaches to create synthetic nanomaterials has led to the…

Designing components that can robustly self-assemble into structures with biological complexity is a grand challenge for material science. Proofreading and error correction is required to improve assembly yield beyond equilibrium limits,…

Soft Condensed Matter · Physics 2023-12-15 Qian-Ze Zhu , Chrisy Xiyu Du , Ella M. King , Michael P. Brenner

Self-assembly is the autonomous organization of components into patterns or structures: an essential ingredient of biology and a desired route to complex organization. At equilibrium, the structure is encoded through specific interactions,…

Soft Condensed Matter · Physics 2018-10-03 Antoine Aubret , Mena Youssef , Stefano Sacanna , Jérémie Palacci

Patchy colloids are promising candidates for building blocks in directed self-assembly. To be successful the surface patterns need to both be simple enough to be synthesized, while feature-rich enough to cause the colloids to self-assemble…

Soft Condensed Matter · Physics 2014-05-13 Erik Edlund , Oskar Lindgren , Martin Nilsson Jacobi

One of the fundamental goals of nanotechnology is to exploit selective and directional interactions between molecules to design particles that self-assemble into desired structures, from capsids, to nano-clusters, to fully formed crystals…

Soft Condensed Matter · Physics 2020-09-16 Flavio Romano , John Russo , Lukáš Kroc , Petr Šulc
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