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Artificial intelligence (AI), particularly machine learning and deep learning models, has significantly impacted bioinformatics research by offering powerful tools for analyzing complex biological data. However, the lack of interpretability…

Artificial Intelligence · Computer Science 2023-12-12 Zhongliang Zhou , Mengxuan Hu , Mariah Salcedo , Nathan Gravel , Wayland Yeung , Aarya Venkat , Dongliang Guo , Jielu Zhang , Natarajan Kannan , Sheng Li

The absence of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. Although various methods of explainable artificial intelligence (XAI) have been suggested, there is a lack of literature that…

Machine Learning · Computer Science 2023-06-22 Aida Brankovic , David Cook , Jessica Rahman , Wenjie Huang , Sankalp Khanna

Artificial Intelligence (AI) models have reached a very significant level of accuracy. While their superior performance offers considerable benefits, their inherent complexity often decreases human trust, which slows their application in…

Machine Learning · Computer Science 2025-04-25 Pierre-Daniel Arsenault , Shengrui Wang , Jean-Marc Patenande

Explainable Artificial Intelligence (XAI) techniques are used to provide transparency to complex, opaque predictive models. However, these techniques are often designed for image and text data, and it is unclear how fit-for-purpose they are…

Computers and Society · Computer Science 2024-10-18 Mythreyi Velmurugan , Chun Ouyang , Yue Xu , Renuka Sindhgatta , Bemali Wickramanayake , Catarina Moreira

An increasing ubiquity of machine learning (ML) motivates research on algorithms to explain ML models and their predictions -- so-called eXplainable Artificial Intelligence (XAI). Despite many survey papers and discussions, the goals and…

Machine Learning · Computer Science 2024-07-16 Moritz Renftle , Holger Trittenbach , Michael Poznic , Reinhard Heil

Regulators have signalled an interest in adopting explainable AI(XAI) techniques to handle the diverse needs for model governance, operational servicing, and compliance in the financial services industry. In this short overview, we review…

Machine Learning · Computer Science 2021-08-13 Jiahao Chen , Victor Storchan

Explainable AI (XAI) has established itself as an important component of AI-driven interactive systems. With Augmented Reality (AR) becoming more integrated in daily lives, the role of XAI also becomes essential in AR because end-users will…

Explainable AI (XAI) is often promoted with the idea of helping users understand how machine learning models function and produce predictions. Still, most of these benefits are reserved for those with specialized domain knowledge, such as…

Artificial Intelligence · Computer Science 2023-04-26 Chinasa T. Okolo

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

Machine Learning · Computer Science 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

There is broad agreement that Artificial Intelligence (AI) systems, particularly those using Machine Learning (ML), should be able to "explain" their behavior. Unfortunately, there is little agreement as to what constitutes an…

Human-Computer Interaction · Computer Science 2022-07-04 Leilani H. Gilpin , Andrew R. Paley , Mohammed A. Alam , Sarah Spurlock , Kristian J. Hammond

AI is becoming increasingly common across different domains. However, as sophisticated AI-based systems are often black-boxed, rendering the decision-making logic opaque, users find it challenging to comply with their recommendations.…

Artificial Intelligence · Computer Science 2024-06-19 Niklas Kühl , Christian Meske , Maximilian Nitsche , Jodie Lobana

With the availability of large datasets and ever-increasing computing power, there has been a growing use of data-driven artificial intelligence systems, which have shown their potential for successful application in diverse areas. However,…

Cryptography and Security · Computer Science 2021-08-05 Jose N. Paredes , Juan Carlos L. Teze , Gerardo I. Simari , Maria Vanina Martinez

With the emergence of Artificial Intelligence (AI)-based decision-making, explanations help increase new technology adoption through enhanced trust and reliability. However, our experimental study challenges the notion that every user…

Human-Computer Interaction · Computer Science 2024-05-01 Sabid Bin Habib Pias , Alicia Freel , Timothy Trammel , Taslima Akter , Donald Williamson , Apu Kapadia

Explainable AI (XAI) aims to support appropriate human-AI reliance by increasing the interpretability of complex model decisions. Despite the proliferation of proposed methods, there is mixed evidence surrounding the effects of different…

Human-Computer Interaction · Computer Science 2024-10-29 Emma Casolin , Flora D. Salim , Ben Newell

In today's data-driven era, computational systems generate vast amounts of data that drive the digital transformation of industries, where Artificial Intelligence (AI) plays a key role. Currently, the demand for eXplainable AI (XAI) has…

Artificial Intelligence · Computer Science 2025-03-07 Georgios Makridis , Vasileios Koukos , Georgios Fatouros , Dimosthenis Kyriazis

Explainable AI (XAI) aims to bridge the gap between complex algorithmic systems and human stakeholders. Current discourse often examines XAI in isolation as either a technological tool, user interface, or policy mechanism. This paper…

Computers and Society · Computer Science 2023-11-28 Joshua L. M. Brand , Luca Nannini

Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation…

Machine Learning · Computer Science 2022-12-09 Weina Jin , Xiaoxiao Li , Mostafa Fatehi , Ghassan Hamarneh

Explainable artificial intelligence (XAI) has predominantly focused on generating model-centric explanations that approximate the behavior of black-box models. However, such explanations often overlook a fundamental aspect of…

Machine Learning · Computer Science 2026-04-22 Salvatore Greco , Jacek Karolczak , Roman Słowiński , Jerzy Stefanowski

This paper systematically derives design dimensions for the structured evaluation of explainable artificial intelligence (XAI) approaches. These dimensions enable a descriptive characterization, facilitating comparisons between different…

Human-Computer Interaction · Computer Science 2020-09-15 Fabian Sperrle , Mennatallah El-Assady , Grace Guo , Duen Horng Chau , Alex Endert , Daniel Keim