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Anatomy is undergoing a renaissance driven by availability of large digital data sets generated by light microscopy. A central computational task is to map individual data volumes to standardized templates. This is accomplished by…
Image segmentation is a fundamental task in computer vision aimed at delineating object boundaries within images. Traditional approaches, such as edge detection and variational methods, have been widely explored, while recent advances in…
The geometric approach to diffeomorphic image registration known as "large deformation by diffeomorphic metric mapping" (LDDMM) is based on a left action of diffeomorphisms on images, and a right-invariant metric on a diffeomorphism group,…
Modelling deformation of anatomical objects observed in medical images can help describe disease progression patterns and variations in anatomy across populations. We apply a stochastic generalisation of the Large Deformation Diffeomorphic…
In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…
In computer vision and medical imaging, the problem of matching structures finds numerous applications from automatic annotation to data reconstruction. The data however, while corresponding to the same anatomy, are often very different in…
In deformable registration, the geometric framework - large deformation diffeomorphic metric mapping or LDDMM, in short - has inspired numerous techniques for comparing, deforming, averaging and analyzing shapes or images. Grounded in…
This paper proposes a new framework and algorithms to address the problem of diffeomorphic registration on a general class of geometric objects that can be described as discrete distributions of local direction vectors. It builds on both…
We introduce a stochastic model of diffeomorphisms, whose action on a variety of data types descends to stochastic evolution of shapes, images and landmarks. The stochasticity is introduced in the vector field which transports the data in…
We present a method to predict image deformations based on patch-wise image appearance. Specifically, we design a patch-based deep encoder-decoder network which learns the pixel/voxel-wise mapping between image appearance and registration…
Cardiac deformation is a crucial biomarker for the evaluation of cardiac function. Current methods for estimating cardiac strain might underestimate local deformation due to through-plane motion and segmental averaging. Mesh-based mapping…
This paper introduces and studies a metamorphosis framework for geometric measures known as varifolds, which extends the diffeomorphic registration model for objects such as curves, surfaces and measures by complementing diffeomorphic…
The simulation of physical phenomena with computer models relies on the estimation of physical and/or numerical parameters calibrated to fit experimental data. The approximations within the computer model and the errors in the measurements…
We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…
In computational anatomy, the statistical analysis of temporal deformations and inter-subject variability relies on shape registration. However, the numerical integration and optimization required in diffeomorphic registration often lead to…
The analysis of manifold-valued data requires efficient tools from Riemannian geometry to cope with the computational complexity at stake. This complexity arises from the always-increasing dimension of the data, and the absence of…
Geometric transformations have been widely used to augment the size of training images. Existing methods often assume a unimodal distribution of the underlying transformations between images, which limits their power when data with…
Accurate tracking of an anatomical landmark over time has been of high interests for disease assessment such as minimally invasive surgery and tumor radiation therapy. Ultrasound imaging is a promising modality benefiting from low-cost and…
Anatomical variabilities seen in longitudinal data or inter-subject data is usually described by the underlying deformation, captured by non-rigid registration of these images. Stationary Velocity Field (SVF) based non-rigid registration…
Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…