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As many other machine learning driven medical image analysis tasks, skin image analysis suffers from a chronic lack of labeled data and skewed class distributions, which poses problems for the training of robust and well-generalizing…

Computer Vision and Pattern Recognition · Computer Science 2018-09-07 Christoph Baur , Shadi Albarqouni , Nassir Navab

Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining…

We propose a new deep learning approach for medical imaging that copes with the problem of a small training set, the main bottleneck of deep learning, and apply it for classification of healthy and cancer cells acquired by quantitative…

Image and Video Processing · Electrical Eng. & Systems 2018-12-31 Moran Rubin , Omer Stein , Nir A. Turko , Yoav Nygate , Darina Roitshtain , Lidor Karako , Itay Barnea , Raja Giryes , Natan T. Shaked

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

Image and Video Processing · Electrical Eng. & Systems 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Deep neural advancements have recently brought remarkable image synthesis performance to the field of image inpainting. The adaptation of generative adversarial networks (GAN) in particular has accelerated significant progress in…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Dongmin Cha , Daijin Kim

We consider unsupervised cell nuclei segmentation in this paper. Exploiting the recently-proposed unpaired image-to-image translation between cell nuclei images and randomly synthetic masks, existing approaches, e.g., CycleGAN, have…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Kai Yao , Kaizhu Huang , Jie Sun , Curran Jude

A major challenge in applying deep learning to medical imaging is the paucity of annotated data. This study demonstrates that synthetic colonoscopy images generated by Generative Adversarial Network (GAN) inversion can be used as training…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Mayank Golhar , Taylor L. Bobrow , Saowanee Ngamruengphong , Nicholas J. Durr

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Existing deep learning-based approaches for histopathology image analysis require large annotated training sets to achieve good performance; but annotating histopathology images is slow and resource-intensive. Conditional generative…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Sujata Butte , Haotian Wang , Min Xian , Aleksandar Vakanski

Generative Adversarial Neural Networks (GANs) are applied to the synthetic generation of prostate lesion MRI images. GANs have been applied to a variety of natural images, is shown show that the same techniques can be used in the medical…

Computer Vision and Pattern Recognition · Computer Science 2017-08-02 Andy Kitchen , Jarrel Seah

We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Caner Mercan , Germonda Reijnen-Mooij , David Tellez Martin , Johannes Lotz , Nick Weiss , Marcel van Gerven , Francesco Ciompi

In recent years, the use of deep learning is becoming increasingly popular in computer vision. However, the effective training of deep architectures usually relies on huge sets of annotated data. This is critical in the medical field where…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Paolo Andreini , Simone Bonechi , Monica Bianchini , Alessandro Mecocci , Franco Scarselli , Andrea Sodi

Although Generative Adversarial Networks (GANs) have shown remarkable success in various tasks, they still face challenges in generating high quality images. In this paper, we propose Stacked Generative Adversarial Networks (StackGAN)…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Han Zhang , Tao Xu , Hongsheng Li , Shaoting Zhang , Xiaogang Wang , Xiaolei Huang , Dimitris Metaxas

In this work, we investigate the problem of face reconstruction given a facial feature representation extracted from a blackbox face recognition engine. Indeed, it is a very challenging problem in practice due to the limitations of…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Thanh-Dat Truong , Chi Nhan Duong , Ngan Le , Marios Savvides , Khoa Luu

Histopathological images of tumors contain abundant information about how tumors grow and how they interact with their micro-environment. Better understanding of tissue phenotypes in these images could reveal novel determinants of…

Image and Video Processing · Electrical Eng. & Systems 2021-04-14 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

In addition to evaluating tumor morphology using H&E staining, immunohistochemistry is used to assess the presence of specific proteins within the tissue. However, this is a costly and labor-intensive technique, for which virtual staining,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 José Teixeira , Pascal Klöckner , Diana Montezuma , Melis Erdal Cesur , João Fraga , Hugo M. Horlings , Jaime S. Cardoso , Sara P. Oliveira

Domain shift between medical images from multicentres is still an open question for the community, which degrades the generalization performance of deep learning models. Generative adversarial network (GAN), which synthesize plausible…

Image and Video Processing · Electrical Eng. & Systems 2020-07-31 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Youbao Tang , Jinzheng Cai , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

Generative learning is a powerful tool for representation learning, and shows particular promise for problems in biomedical imaging. However, in this context, sampling from the distribution is secondary to finding representations of real…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Simon Myles Thomas

This work is about the semantic segmentation of skin lesion boundary and their attributes using Image-to-Image Translation with Conditional Adversarial Nets. Melanoma is a type of skin cancer that can be cured if detected in time.…

Image and Video Processing · Electrical Eng. & Systems 2021-02-02 Cristian Lazo