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Machine learning potentials are an important tool for molecular simulation, but their development is held back by a shortage of high quality datasets to train them on. We describe the SPICE dataset, a new quantum chemistry dataset for…

The attention mechanism is a core component of the Transformer architecture. Various methods have been developed to compute attention scores, including multi-head attention (MHA), multi-query attention, group-query attention and so on. We…

Neural Networks (NNs) are effective models for refining the accuracy of molecular dynamics, opening up new fields of application. Typically trained bottom-up, atomistic NN potential models can reach first-principle accuracy, while…

Chemical Physics · Physics 2025-05-19 Paul Fuchs , Stephan Thaler , Sebastien Röcken , Julija Zavadlav

Atomistic simulations are a powerful tool for studying the dynamics of molecules, proteins, and materials on wide time and length scales. Their reliability and predictiveness, however, depend directly on the accuracy of the underlying…

Chemical Physics · Physics 2024-11-28 Silvan Käser , Debasish Koner , Markus Meuwly

Machine-learned potential energy surfaces (PESs) for molecules with more than 10 atoms are typically forced to use lower-level electronic structure methods such as density functional theory and second-order Moller-Plesset perturbation…

Chemical Physics · Physics 2021-05-21 Chen Qu , Paul Houston , Riccardo Conte , Apurba Nandi , Joel M. Bowman

We present an evaluation of CSP-MACE-{\AA}, a machine learning interatomic potential intended to replace DFT in crystal structure prediction (CSP). We decompose the total energy into separate intramolecular and intermolecular components.…

Modeling non-empirical and highly flexible interatomic potential energy surfaces (PES) using machine learning (ML) approaches is becoming popular in molecular and materials research. Training an ML-PES is typically performed in two stages:…

Materials Science · Physics 2021-01-05 Suresh Kondati Natarajan , Miguel A. Caro

Transfer learning has become crucial in computer vision tasks due to the vast availability of pre-trained deep learning models. However, selecting the optimal pre-trained model from a diverse pool for a specific downstream task remains a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Xiaotong Li , Zixuan Hu , Yixiao Ge , Ying Shan , Ling-Yu Duan

Developing machine learning-based interatomic potentials from ab-initio electronic structure methods remains a challenging task for computational chemistry and materials science. This work studies the capability of transfer learning, in…

Computational Physics · Physics 2023-03-22 Viktor Zaverkin , David Holzmüller , Luca Bonfirraro , Johannes Kästner

Attention regulates information transfer between tokens. For this, query and key vectors are compared, typically in terms of a scalar product, $\mathbf{Q}^T\mathbf{K}$, together with a subsequent softmax normalization. In geometric terms,…

Machine Learning · Computer Science 2025-08-11 Claudius Gros

We are witnessing rapid progress in automatically generating and manipulating 3D assets due to the availability of pretrained text-image diffusion models. However, time-consuming optimization procedures are required for synthesizing each…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Etai Sella , Gal Fiebelman , Noam Atia , Hadar Averbuch-Elor

The predictive simulation of molecular liquids requires models that are not only accurate, but computationally efficient enough to handle the large systems and long time scales required for reliable prediction of macroscopic properties. We…

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches. As a widely applied powerful technique in…

Computation and Language · Computer Science 2024-04-24 Yang Tan , Mingchen Li , Bingxin Zhou , Bozitao Zhong , Lirong Zheng , Pan Tan , Ziyi Zhou , Huiqun Yu , Guisheng Fan , Liang Hong

Much of recent Deep Reinforcement Learning success is owed to the neural architecture's potential to learn and use effective internal representations of the world. While many current algorithms access a simulator to train with a large…

Artificial Intelligence · Computer Science 2022-02-03 Amir Ardalan Kalantari , Mohammad Amini , Sarath Chandar , Doina Precup

Online Passive-Aggressive (PA) learning is a class of online margin-based algorithms suitable for a wide range of real-time prediction tasks, including classification and regression. PA algorithms are formulated in terms of deterministic…

Machine Learning · Statistics 2015-09-09 Arnold Salas , Stephen J. Roberts , Michael A. Osborne

We present a novel method for Efficient training with Progressive Activation Sharing (EPAS). This method bridges progressive training paradigm with the phenomenon of redundant QK (or KV ) activations across deeper layers of transformers.…

Machine Learning · Computer Science 2026-01-28 Rezaul Karim , Maryam Dialameh , Yang Liu , Boxing Chen , Walid Ahmed

Self-attention mechanism has been widely used for various tasks. It is designed to compute the representation of each position by a weighted sum of the features at all positions. Thus, it can capture long-range relations for computer vision…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xia Li , Zhisheng Zhong , Jianlong Wu , Yibo Yang , Zhouchen Lin , Hong Liu

Machine learning methods have nowadays become easy-to-use tools for constructing high-dimensional interatomic potentials with ab initio accuracy. Although machine learned interatomic potentials are generally orders of magnitude faster than…

Computational Physics · Physics 2021-02-24 Yaolong Zhang , Ce Hu , Bin Jiang

Machine learning interatomic potentials (MLIPs) have revolutionized the modeling of materials and molecules by directly fitting to ab initio data. However, while these models excel at capturing local and semi-local interactions, they often…

Prioritized Experience Replay (PER) is a technical means of deep reinforcement learning by selecting experience samples with more knowledge quantity to improve the training rate of neural network. However, the non-uniform sampling used in…

Machine Learning · Computer Science 2023-10-10 Zhuoying Chen , Huiping Li , Rizhong Wang