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Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Time-lapse fluorescent microscopy (TLFM) combined with predictive mathematical modelling is a powerful tool to study the inherently dynamic processes of life on the single-cell level. Such experiments are costly, complex and labour…

Computer Vision and Pattern Recognition · Computer Science 2021-09-27 Christoph Reich , Tim Prangemeier , Christian Wildner , Heinz Koeppl

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can…

Computational Engineering, Finance, and Science · Computer Science 2015-10-20 Dagmar Iber , Zahra Karimaddini , Erkan Ünal

Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…

Quantitative Methods · Quantitative Biology 2024-03-05 Baiyang Dai , Jiamin Yang , Hari Shroff , Patrick La Riviere

Estimation of a single leaf area can be a measure of crop growth and a phenotypic trait to breed new varieties. It has also been used to measure leaf area index and total leaf area. Some studies have used hand-held cameras, image processing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Namal Jayasuriya , Yi Guo , Wen Hu , Oula Ghannoum

High-dimensional feature selection is a central problem in a variety of application domains such as machine learning, image analysis, and genomics. In this paper, we propose graph-based tests as a useful basis for feature selection. We…

Methodology · Statistics 2024-08-13 Swarnadip Ghosh , Somabha Mukherjee , Divyansh Agarwal , Yichen He , Mingzhi Song , Xuejiao Pei

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

This paper proposes a novel algorithm for the problem of structural image segmentation through an interactive model-based approach. Interaction is expressed in the model creation, which is done according to user traces drawn over a given…

Computer Vision and Pattern Recognition · Computer Science 2008-05-16 Alexandre Noma , Ana B. V. Graciano , Luis Augusto Consularo , Roberto M. Cesar-Jr , Isabelle Bloch

We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood…

Quantitative Methods · Quantitative Biology 2020-05-29 G. Simionato , K. Hinkelmann , R. Chachanidze , P. Bianchi , E. Fermo , R. van Wijk , M. Leonetti , C. Wagner , L. Kaestner , S. Quint

The rapid development of deep learning has made a great progress in image segmentation, one of the fundamental tasks of computer vision. However, the current segmentation algorithms mostly rely on the availability of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Wei Shen , Zelin Peng , Xuehui Wang , Huayu Wang , Jiazhong Cen , Dongsheng Jiang , Lingxi Xie , Xiaokang Yang , Qi Tian

3D human segmentation has seen noticeable progress in re-cent years. It, however, still remains a challenge to date. In this paper, weintroduce a deep patch-based method for 3D human segmentation. Wefirst extract a local surface patch for…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Dongbo Zhang , Zheng Fang , Xuequan Lu , Hong Qin , Antonio Robles-Kelly , Chao Zhang , Ying He

This paper proposes a DNN-based system that detects multiple people from a single depth image. Our neural network processes a depth image and outputs a likelihood map in image coordinates, where each detection corresponds to a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 David Fuentes-Jimenez , Cristina Losada-Gutierrez , David Casillas-Perez , Javier Macias-Guarasa , Roberto Martin-Lopez , Daniel Pizarro , Carlos A. Luna

The rapid growth in feature dimension may introduce implicit associations between features and labels in multi-label datasets, making the relationships between features and labels increasingly complex. Moreover, existing methods often adopt…

Machine Learning · Computer Science 2025-05-30 Wanfu Gao , Jun Gao , Qingqi Han , Hanlin Pan , Kunpeng Liu

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Learning-based 3D shape segmentation is usually formulated as a semantic labeling problem, assuming that all parts of training shapes are annotated with a given set of tags. This assumption, however, is impractical for learning fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2022-01-14 Xiaogang Wang , Xun Sun , Xinyu Cao , Kai Xu , Bin Zhou

We present feature finding and tracking algorithms in 3D in living cells, and demonstrate their utility to measure metrics important in cell biological processes. We developed a computational imaging hybrid approach that combines automated…

Biological Physics · Physics 2015-04-06 Kemp Plumb , Sarah Elaz , Vincent Pelletier , Maria L. Kilfoil

Deep learning has proven to yield fast and accurate predictions of quantum-chemical properties to accelerate the discovery of novel molecules and materials. As an exhaustive exploration of the vast chemical space is still infeasible, we…

Machine Learning · Statistics 2020-01-10 Niklas W. A. Gebauer , Michael Gastegger , Kristof T. Schütt
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