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Modulation-enhanced localization microscopy (MELM) has demonstrated significant improvements in both lateral and axial localization precision compared to conventional single-molecule localization microscopy (SMLM). However, lateral…

Fluorescence lifetime imaging microscopy (FLIM) is an important technique to understand the chemical micro-environment in cells and tissues since it provides additional contrast compared to conventional fluorescence imaging. When two…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Varun Mannam , Xiaotong Yuan , Scott Howard

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

Optics · Physics 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

Fluorescence lifetime imaging microscopy (FLIM) provides detailed information about molecular interactions and biological processes. A major bottleneck for FLIM is image resolution at high acquisition speeds, due to the engineering and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Valentin Kapitány , Areeba Fatima , Vytautas Zickus , Jamie Whitelaw , Ewan McGhee , Robert Insall , Laura Machesky , Daniele Faccio

This paper introduces an innovative approach to silicon and glass via inspection, which combines hybrid field microscopy with photometric stereo. Conventional optical microscopy techniques are generally limited to superficial inspections…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Gugeong Sung

When capturing images in low-light conditions, the images often suffer from low visibility, which not only degrades the visual aesthetics of images, but also significantly degenerates the performance of many computer vision algorithms. In…

Computer Vision and Pattern Recognition · Computer Science 2020-12-17 Lijun Zhang , Xiao Liu , Erik Learned-Miller , Hui Guan

Multiple-input multiple-output (MIMO) orthogonal frequency-division multiplexing (OFDM) systems rely on digital or hybrid digital and analog designs for beamforming against frequency-selective fading, which suffer from high hardware…

Signal Processing · Electrical Eng. & Systems 2026-01-26 Zheao Li , Jiancheng An , Chau Yuen

We present the first on-sky results of the micro-lens ring tip-tilt (MLR-TT) sensor. This sensor utilizes a 3D printed micro-lens ring feeding six multi-mode fibers to sense misaligned light, allowing centroid reconstruction. A tip-tilt…

Single Pixel (SP) imaging is now a reality in many applications, e.g., biomedical ultrathin endoscope and fluorescent spectroscopy. In this context, many schemes exist to improve the light throughput of these device, e.g., using structured…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

Line Intensity Mapping (LIM) is a new observational technique that uses low-resolution observations of line emission to efficiently trace the large-scale structure of the Universe out to high redshift. Common mm/sub-mm emission lines are…

Diffuse optical imaging (DOI) offers valuable insights into scattering mediums, but the quest for high-resolution imaging often requires dense sampling strategies, leading to higher imaging errors and lengthy acquisition times. This work…

Optics · Physics 2025-04-07 Ben Wiesel , Shlomi Arnon

Low-light image super-resolution (LLSR) is a challenging task due to the coupled degradation of low resolution and poor illumination. To address this, we propose the Guided Texture and Feature Modulation Network (GTFMN), a novel framework…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Yongsong Huang , Tzu-Hsuan Peng , Tomo Miyazaki , Xiaofeng Liu , Chun-Ting Chou , Ai-Chun Pang , Shinichiro Omachi

Atomic-resolution scanning transmission electron microscopy (STEM) characterization requires precise tilting of the specimen to high symmetric zone axis, which is usually processed in reciprocal space by following the diffraction patterns.…

Materials Science · Physics 2024-06-04 Jiake Wei , Zhangze Xu , Wenjie Shen , Bin Feng , Ryo Ishikawa , Naoya Shibata , Yuichi Ikuhara , Xuedong Bai

Stacked intelligent metasurface (SIM) and dual-polarized SIM (DPSIM) enabled wave-domain signal processing have emerged as promising research directions for offloading baseband digital processing tasks and efficiently simplifying…

Signal Processing · Electrical Eng. & Systems 2025-10-07 Yida Zhang , Qiuyan Liu , Hongtao Luo , Yuqi Xia , Qiang Wang , Fuchang Li , Xiaofeng Tao , Yuanwei Liu

We propose a 3D super-resolution approach to improve both lateral and axial spatial resolution in Total Internal Reflectance Fluorescence (TIRF) imaging applications. Our approach, called 3D-COL0RME (3D - Covariance-based $\ell_0$…

Medical Physics · Physics 2022-07-12 Vasiliki Stergiopoulou , Luca Calatroni , Sébastien Schaub , Laure Blanc-Féraud

Multi-image super-resolution (MISR) is a critical technique for satellite remote sensing. In the perspective of information, twin-image super-resolution (TISR) is regarded as the most challenging MISR scenario, having crucial applications…

Image and Video Processing · Electrical Eng. & Systems 2026-02-26 Chia-Hsiang Lin , Wei-Chih Liu , Yu-En Chiu , Jhao-Ting Lin

Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information revealing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal…

An integrated photonic platform with anchored-membrane structures, the T-Guide, is proposed and numerically investigated. These compact air-clad structures have high index contrast and are much more stable than prior membrane-type…

Optics · Physics 2016-08-24 Jeff Chiles , Sasan Fathpour

The resolution of optical imaging devices is ultimately limited by the diffraction of light. To circumvent this limit, modern super-resolution microscopy techniques employ active interaction with the object by exploiting its optical…

Optics · Physics 2022-01-05 A. A. Pushkina , G. Maltese , J. I. Costa-Filho , P. Patel , A. I. Lvovsky

We proposed a Smartphone-based Optical Sectioning (SOS) microscope based on the HiLo technique, with a single smartphone replacing a high-cost illumination source and a camera sensor.We built our SOS with off-the-shelf optical mechanical…