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Evidence-based knowledge of infectious disease burden, including prevalence, incidence, severity and transmission, in different population strata and locations, and possibly in real time, is crucial to the planning and evaluation of public…

Methodology · Statistics 2018-08-14 Daniela De Angelis , Anne M. Presanis

Studying the effects of one-way variation of any number of parameters on any number of output probabilities quickly becomes infeasible in practice, especially if various evidence profiles are to be taken into consideration. To provide for…

Artificial Intelligence · Computer Science 2012-07-09 Silja Renooij , Linda C. van der Gaag

Identifying important nodes for disease spreading is a central topic in network epidemiology. We investigate how well the position of a node, characterized by standard network measures, can predict its epidemiological importance in any…

Populations and Evolution · Quantitative Biology 2020-07-28 Doina Bucur , Petter Holme

The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

Populations and Evolution · Quantitative Biology 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

Phenomenological models are highly effective tools for forecasting disease dynamics using real world data, particularly in scenarios where detailed knowledge of disease mechanisms is limited. However, their reliability depends on the model…

Quantitative Methods · Quantitative Biology 2025-03-31 Yuganthi R. Liyanage , Gerardo Chowell , Gleb Pogudin , Necibe Tuncer

Metapopulation epidemic models are a valuable tool for studying large-scale outbreaks. With the limited availability of epidemic tracing data, it is challenging to infer the essential constituents of these models, namely, the epidemic…

Machine Learning · Computer Science 2026-03-04 Xin Li , Jonathan Cohen , Shai Pilosof , Rami Puzis

We study some simple models of disease transmission on small-world networks, in which either the probability of infection by a disease or the probability of its transmission is varied, or both. The resulting models display epidemic behavior…

Statistical Mechanics · Physics 2009-10-31 Cristopher Moore , M. E. J. Newman

Infectious disease remains, despite centuries of work to control and mitigate its effects, a major problem facing humanity. This paper reviews the mathematical modelling of infectious disease epidemics on networks, starting from the…

Popular Physics · Physics 2015-06-03 Thomas House

Several systems can be modeled as sets of interdependent networks where each network contains distinct nodes. Diffusion processes like the spreading of a disease or the propagation of information constitute fundamental phenomena occurring…

Social and Information Networks · Computer Science 2015-06-23 Mostafa Salehi , Payam Siyari , Matteo Magnani , Danilo Montesi

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

Populations and Evolution · Quantitative Biology 2013-08-08 Ling Xue , Caterina Scoglio

We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

Populations and Evolution · Quantitative Biology 2012-02-14 Artem S. Novozhilov

Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

Since roughly a decade ago, network science has focused among others on the problem of how the spreading of diseases depends on structural patterns. Here, we contribute to further advance our understanding of epidemic spreading processes by…

Computational Physics · Physics 2012-06-11 Sergio Gomez , Jesus Gomez-Gardenes , Yamir Moreno , Alex Arenas

In some estimation problems, especially in applications dealing with information theory, signal processing and biology, theory provides us with additional information allowing us to restrict the parameter space to a finite number of points.…

Methodology · Statistics 2012-07-25 Christine Choirat , Raffaello Seri

Mathematical disease modelling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen spreading among a population. This paradigm has been useful in simplifying the biological reality…

Populations and Evolution · Quantitative Biology 2021-06-02 Blake J. M. Williams , Guillaume St-Onge , Laurent Hébert-Dufresne

Network models are used to study interconnected systems across many physical, biological, and social disciplines. Such models often assume a particular network-generating mechanism, which when fit to data produces estimates of…

Social and Information Networks · Computer Science 2022-01-17 Ryan E. Langendorf , Matthew G. Burgess

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

Populations and Evolution · Quantitative Biology 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

Epidemic threshold is one of the most important features of the epidemic dynamics. Through a lot of numerical simulations in classic Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Susceptible (SIS) models on various types of…

Physics and Society · Physics 2014-10-16 Panpan Shu , Wei Wang , Ming Tang , Younghae Do

Epidemiological contact network models have emerged as an important tool in understanding and predicting the spread of infectious disease, due to their capacity to engage individual heterogeneity that may underlie essential dynamics of a…

Physics and Society · Physics 2019-10-28 Jack Leitch , Kathleen A. Alexander , Srijan Sengupta
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