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The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

We use the persistent homology method of topological data analysis and dimensional analysis techniques to study data of syntactic structures of world languages. We analyze relations between syntactic parameters in terms of dimensionality,…

Computation and Language · Computer Science 2019-03-14 Alexander Port , Taelin Karidi , Matilde Marcolli

Data quality is crucial for the successful training, generalization and performance of machine learning models. We propose to measure the quality of a subset concerning the dataset it represents, using topological data analysis techniques.…

Algebraic Topology · Mathematics 2024-10-01 Álvaro Torras-Casas , Eduardo Paluzo-Hidalgo , Rocio Gonzalez-Diaz

In this paper, we present a flexible and probabilistic framework for tracking topological features in time-varying scalar fields using merge trees and partial optimal transport. Merge trees are topological descriptors that record the…

Computational Geometry · Computer Science 2025-08-26 Mingzhe Li , Xinyuan Yan , Lin Yan , Tom Needham , Bei Wang

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

The value proposition of a dataset often resides in the implicit interconnections or explicit relationships (patterns) among individual entities, and is often modeled as a graph. Effective visualization of such graphs can lead to key…

Databases · Computer Science 2017-02-14 Yang Zhang , Yusu Wang , Srinivasan Parthasarathy

Topological Machine Learning (TML) is an emerging field that leverages techniques from algebraic topology to analyze complex data structures in ways that traditional machine learning methods may not capture. This tutorial provides a…

Machine Learning · Computer Science 2024-09-05 Baris Coskunuzer , Cüneyt Gürcan Akçora

Persistent homology computes the multiscale topology of a data set by using a sequence of discrete complexes. In this paper, we propose that persistent homology may be a useful tool for studying the structure of the landscape of string…

High Energy Physics - Theory · Physics 2019-04-24 Alex Cole , Gary Shiu

We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

Statistical analysis on object data presents many challenges. Basic summaries such as means and variances are difficult to compute. We apply ideas from topology to study object data. We present a framework for using persistence landscapes…

Methodology · Statistics 2019-12-12 Vic Patrangenaru , Peter Bubenik , Robert L. Paige , Daniel Osborne

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

Spatial relationships in multi-species data can indicate and affect system outcomes and behaviors, ranging from disease progression in cancer to coral reef resilience in ecology; therefore, quantifying these relationships is an important…

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez

Persistent homology is a cornerstone of topological data analysis, offering a multiscale summary of topology with robustness to nuisance transformations, such as rotations and small deformations. Persistent homology has seen broad use…

Methodology · Statistics 2025-11-19 Zitian Wu , Arkaprava Roy , Leo L. Duan

Much information about a graph can be obtained by studying its spanning trees. On the other hand, a graph can be regarded as a 1-dimensional cell complex, raising the question of developing a theory of trees in higher dimension. As observed…

Combinatorics · Mathematics 2015-06-24 Art M. Duval , Caroline J. Klivans , Jeremy L. Martin

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

The visualization of hierarchically structured data over time is an ongoing challenge and several approaches exist trying to solve it. Techniques such as animated or juxtaposed tree visualizations are not capable of providing a good…

Graphics · Computer Science 2020-02-11 Fabian Bolte , Mahsan Nourani , Eric D. Ragan , Stefan Bruckner

Complex systems are difficult to study not only because they are nonlinear, multiscale, and often nonstationary, but because their scientifically relevant organization is often invisible at the level of individual components, pairwise…

Physics and Society · Physics 2026-03-30 Mark M. Bailey

Merge trees are a powerful tool from topological data analysis that is frequently used to analyze scalar fields. The similarity between two merge trees can be captured by an interleaving: a pair of maps between the trees that jointly…