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Automated insulin delivery for Type 1 Diabetes must balance glucose control and safety under uncertain meals and physiological variability. While reinforcement learning (RL) enables adaptive personalization, existing approaches struggle to…

Machine Learning · Computer Science 2026-01-23 Yushen Liu , Yanfu Zhang , Xugui Zhou

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

Machine Learning · Computer Science 2025-11-27 Mirko Paolo Barbato , Giorgia Rigamonti , Davide Marelli , Paolo Napoletano

We present a versatile NeRF-based simulator for testing autonomous driving (AD) software systems, designed with a focus on sensor-realistic closed-loop evaluation and the creation of safety-critical scenarios. The simulator learns from…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 William Ljungbergh , Adam Tonderski , Joakim Johnander , Holger Caesar , Kalle Åström , Michael Felsberg , Christoffer Petersson

Blood glucose prediction is an important component of biomedical technology for managing diabetes with automated insulin delivery systems. Machine learning and deep learning algorithms hold the potential to advance this technology. However,…

Software Engineering · Computer Science 2024-06-14 Miriam K. Wolff , Sam Royston , Anders Lyngvi Fougner , Hans Georg Schaathun , Martin Steinert , Rune Volden

Large clinical evidence acknowledges the crucial role played by physical activity in delaying the progression of type-2 diabetes. However, the literature lacks control approaches that leverage exercise for type-2 diabetes control and more…

Systems and Control · Electrical Eng. & Systems 2025-01-23 Pierluigi Francesco De Paola , Alessandro Borri , Fabrizio Dabbene , Pasquale Palumbo , Alessia Paglialonga

We present a shared control paradigm that improves a user's ability to operate complex, dynamic systems in potentially dangerous environments without a priori knowledge of the user's objective. In this paradigm, the role of the autonomous…

Robotics · Computer Science 2019-06-07 Alexander Broad , Todd Murphey , Brenna Argall

Every year, humanity loses about 1.5 million persons due to diabetic disease. Therefore continuous monitoring of diabetes is highly needed, but the conventional approach, i.e., fingertip pricking, causes mental and physical pain to the…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Abdelrhman Y. Soliman , Ahmed M. Nor , Octavian Fratu , Simona Halunga , Osama A. Omer , Ahmed S. Mubark

The growing worldwide incidence of diabetes requires more effective approaches for managing blood glucose levels. Insulin delivery systems have advanced significantly, with artificial intelligence (AI) playing a key role in improving their…

Artificial Intelligence · Computer Science 2025-03-25 Maria Panagiotou , Knut Stroemmen , Lorenzo Brigato , Bastiaan E. de Galan , Stavroula Mougiakakou

Autonomous driving has gained significant advancements in recent years. However, obtaining a robust control policy for driving remains challenging as it requires training data from a variety of scenarios, including rare situations (e.g.,…

Robotics · Computer Science 2019-07-23 Weizi Li , David Wolinski , Ming C. Lin

Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. Clinical decision support systems incorporating artificial intelligence (AI-CDSS) can assist medical professionals in diagnosing type 2…

Machine Learning · Computer Science 2026-02-13 Mujeeb Ur Rehman , Imran Rehan , Sohail Khalid

Autonomous vehicles (AV) depend on the sensors like RADAR and camera for the perception of the environment, path planning, and control. With the increasing autonomy and interactions with the complex environment, there have been growing…

Systems and Control · Computer Science 2021-06-22 Abu Hasnat Mohammad Rubaiyat , Yongming Qin , Homa Alemzadeh

Autonomous driving has shown great potential to reform modern transportation. Yet its reliability and safety have drawn a lot of attention and concerns. Compared with traditional software systems, autonomous driving systems (ADSs) often use…

Software Engineering · Computer Science 2022-09-26 Guannan Lou , Yao Deng , Xi Zheng , Mengshi Zhang , Tianyi Zhang

Continuous glucose monitoring (CGM) provides dense and dynamic glucose profiles that enable reliable estimation of Ambulatory Glucose Profile (AGP) metrics, such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR).…

Machine Learning · Computer Science 2025-10-09 Canyu Lei , Benjamin Lobo , Jianxin Xie

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

Pramlintide's capability to delay gastric emptying has motivated its use in artificial pancreas systems, accompanying insulin as a control action. Due to the scarcity of pramlintide simulation models in the literature, in silico testing of…

Systems and Control · Electrical Eng. & Systems 2025-06-24 Borja Pons Torres , Iván Sala Mira , Clara Furió-Novejarque , Ricardo Sanz , Pedro García , José-Luis Díez , Jorge Bondia

Objective - This work introduces Dareplane, a modular and broad technology-agnostic open source software platform for brain-computer interface research with an application focus on adaptive deep brain stimulation (aDBS). One difficulty for…

Other Quantitative Biology · Quantitative Biology 2025-02-19 Matthias Dold , Joana Pereira , Bastian Sajonz , Volker A. Coenen , Jordy Thielen , Marcus L. F. Janssen , Michael Tangermann

Background and Objective: Diabetes presents a significant challenge to healthcare due to the negative impact of poor blood sugar control on health and associated complications. Computer simulation platforms, notably exemplified by the…

Applications · Statistics 2024-09-10 Mohammadreza Ganji , Anas El Fathi , Chiara Fabris , Dayu Lv , Boris Kovatchev , Marc Breton

The algorithms developed for Maritime Autonomous Surface Ships (MASS) are often challenging to test on actual vessels due to high operational costs and safety considerations. Simulations offer a cost-effective alternative and eliminate…

In this work, we present SafePlanner, a systematic testing framework for identifying safety-critical flaws in the Plan model of Automated Driving Systems (ADS). SafePlanner targets two core challenges: generating structurally meaningful…

Software Engineering · Computer Science 2026-01-15 Dohyun Kim , Sanggu Han , Sangmin Woo , Joonha Jang , Jaehoon Kim , Changhun Song , Yongdae Kim
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