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We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

We study how a fraction of a population should be vaccinated to most efficiently top epidemics. We argue that only local information (about the neighborhood of specific vertices) is usable in practice, and hence we consider only local…

Populations and Evolution · Quantitative Biology 2007-05-23 Petter Holme

The graph invariant examined in this paper is the largest eigenvalue of the adjacency matrix of a graph. Previous work demonstrates the tight relationship between this invariant, the birth and death rate of a contagion spreading on the…

Social and Information Networks · Computer Science 2022-10-27 V. Cherniavskyi , G. Dennis , S. R. Kingan

We analyze an epidemic model on a network consisting of susceptible-infected-recovered equations at the nodes coupled by diffusion using a graph Laplacian. We introduce an epidemic criterion and examine different vaccination/containment…

Physics and Society · Physics 2020-09-25 F. Bustamante-Castaneda , J. -G. Caputo , G. Cruz-Pacheco , A. Knippel , F. Mouatamide

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have…

Optimization and Control · Mathematics 2014-12-09 Shuo Han , Victor M. Preciado , Cameron Nowzari , George J. Pappas

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

Populations and Evolution · Quantitative Biology 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri

Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a…

Physics and Society · Physics 2019-02-19 Xiao-Long Peng , Ze-Qiong Zhang , Junyuan Yang , Zhen Jin

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Vaccination is an important measure available for preventing or reducing the spread of infectious diseases. In this paper, an epidemic model including susceptible, infected, and imperfectly vaccinated compartments is studied on…

Physics and Society · Physics 2015-06-15 Xiao-Long Peng , Xin-Jian Xu , Xinchu Fu , Tao Zhou

We investigate methods to vaccinate contact networks -- i.e. removing nodes in such a way that disease spreading is hindered as much as possible -- with respect to their cost-efficiency. Any real implementation of such protocols would come…

Populations and Evolution · Quantitative Biology 2017-11-01 Petter Holme , Nelly Litvak

Epidemics occur in all shapes and forms: infections propagating in our sparse sexual networks, rumours and diseases spreading through our much denser social interactions, or viruses circulating on the Internet. With the advent of large…

Physics and Society · Physics 2013-09-02 Laurent Hébert-Dufresne , Antoine Allard , Jean-Gabriel Young , Louis J. Dubé

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

The way diseases spread through schools, epidemics through countries, and viruses through the Internet is crucial in determining their risk. Although each of these threats has its own characteristics, its underlying network determines the…

Physics and Society · Physics 2011-12-20 Christian M. Schneider , Tamara Mihaljev , Shlomo Havlin , Hans J. Herrmann

We study the effect of vaccination on robustness of networks against propagating attacks that obey the susceptible-infected-removed model.By extending the generating function formalism developed by Newman (2005), we analytically determine…

Physics and Society · Physics 2011-09-27 Takehisa Hasegawa , Naoki Masuda

Given a network of nodes, minimizing the spread of a contagion using a limited budget is a well-studied problem with applications in network security, viral marketing, social networks, and public health. In real graphs, virus may infect a…

Discrete Mathematics · Computer Science 2017-11-03 Muhammad Ahmad , Juvaria Tariq , Mudassir Shabbir , Imdadullah Khan

The decision of whether or not to vaccinate is a complex one. It involves the contribution both to a social good -- herd immunity -- and to one's own well being. It is informed by social influence, personal experience, education, and mass…

Populations and Evolution · Quantitative Biology 2022-02-15 Soya Miyoshi , Marko Jusup , Petter Holme

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…

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