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The contact process is an emblematic model of a non-equilibrium system, containing a phase transition between inactive and active dynamical regimes. In the epidemiological context, the model is known as the susceptible-infected-susceptible…

Statistical Mechanics · Physics 2023-05-12 Wout Merbis , Clélia de Mulatier , Philippe Corboz

The Quasi Steady-State (QSS) model of long-term dynamics relies on the idea of time-scale decomposition. Assuming that the fast variables are infinitely fast and are stable in the long-term, the QSS model replaces the differential equations…

Systems and Control · Computer Science 2013-10-02 Xiaozhe Wang , Hsiao-Dong Chiang

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

Populations and Evolution · Quantitative Biology 2017-09-04 Majid Jaberi Douraki

We study that the breakdown of epidemic depends on some parameters, that is expressed in epidemic reproduction ratio number. It is noted that when $R_0 $ exceeds 1, the stochastic model have two different results. But, eventually the…

Statistics Theory · Mathematics 2018-03-19 Kurnia Susvitasari

Quasi-stationary distributions (QSD) have been widely studied since the pioneering work of Kolmogorov (1938), Yaglom (1947) and Sevastyanov (1951). They appear as a natural object when considering Markov processes that are certainly…

Probability · Mathematics 2012-06-29 Pablo Groisman , Matthieu Jonckheere

This paper analyzes a Susceptible-Infected-Susceptible (SIS) model of epidemic propagation over hypergraphs and, motivated by an important special case, we refer to the model as to the simplicial SIS model. Classically, the multi-group SIS…

Optimization and Control · Mathematics 2021-10-05 Pedro Cisneros-Velarde , Francesco Bullo

In the modelling of stochastic phenomena, such as quasi-reaction systems, parameter estimation of kinetic rates can be challenging, particularly when the time gap between consecutive measurements is large. Local linear approximation…

Methodology · Statistics 2026-03-10 Matteo Framba , Veronica Vinciotti , Ernst C. Wit

For the continuous-time $\lambda$-recurrent jump process, the $\lambda$-recurrence assures the existence of quasi-stationary distribution when it has finite exit states (the states that have positive killing rates). And we give an explicit…

Probability · Mathematics 2024-07-30 Qian Du , Yong-Hua Mao

We analyse the effect of intrinsic fluctuations on the properties of bistable stochastic systems with time scale separation operating under1 quasi-steady state conditions. We first formulate a stochastic generalisation of the quasi-steady…

Biological Physics · Physics 2016-03-02 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Efficient analysis and simulation of multiscale stochastic systems of chemical kinetics is an ongoing area for research, and is the source of many theoretical and computational challenges. In this paper, we present a significant improvement…

Numerical Analysis · Mathematics 2016-09-21 Simon Cotter

A preceding paper demonstrated that explicit asymptotic methods generally work much better for extremely stiff reaction networks than has previously been shown in the literature. There we showed that for systems well removed from…

Solar and Stellar Astrophysics · Physics 2022-10-19 M. W. Guidry , J. A. Harris

Spectral clustering is a widely used method for community detection in networks. We focus on a semi-supervised community detection scenario in the Partially Labeled Stochastic Block Model (PL-SBM) with two balanced communities, where a…

Statistics Theory · Mathematics 2024-12-16 Nicolas Fraiman , Michael Nisenzon

We study stochastic pairwise interaction network systems whereby a finite population of agents, identified with the nodes of a graph, update their states in response to both individual mutations and pairwise interactions with their…

Systems and Control · Electrical Eng. & Systems 2024-10-31 Giacomo Como , Fabio Fagnani , Sandro Zampieri

We discuss parameter dependent polynomial ordinary differential equations that model chemical reaction networks. By classical quasi-steady state (QSS) reduction we understand the following familiar heuristic: Set the rate of change for…

Classical Analysis and ODEs · Mathematics 2022-09-20 Alexandra Goeke , Sebastian Walcher , Eva Zerz

We numerically study the dynamics of the SIR disease model on small-world networks by using a large-deviation approach. This allows us to obtain the probability density function of the total fraction of infected nodes and of the maximum…

Physics and Society · Physics 2022-09-01 Yannick Feld , Alexander K. Hartmann

Exact discrete-time models of nonlinear systems are difficult or impossible to obtain, and hence approximate models may be employed for control design. Most existing results provide conditions under which the stability of the approximate…

Systems and Control · Electrical Eng. & Systems 2022-07-15 Alexis J. Vallarella , Paula Cardone , Hernan Haimovich

This paper studies the spread dynamics of a stochastic SIRS epidemic model with nonlinear incidence and varying population size, which is formulated as a piecewise deterministic Markov process. A threshold dynamic determined by the basic…

Dynamical Systems · Mathematics 2017-10-26 Dan Li , Shengqiang Liu , Jing'an Cui

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

Populations and Evolution · Quantitative Biology 2023-05-31 Sei Zhen Khong , Lanlan Su

The quasi-static evolution of steady states far from equilibrium is investigated from the point of view of quantum statistical mechanics. As a concrete example of a thermodynamic system, a two-level quantum dot coupled to several reservoirs…

Mathematical Physics · Physics 2009-11-11 Walid K. Abou Salem

Stochastic diffusion is the noisy and uncertain process through which dynamics like epidemics, or agents like animal species, disperse over a larger area. Understanding these processes is becoming increasingly important as we attempt to…