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Flow cytometry is a cornerstone technique in medical and biological research, providing crucial information about cell size and granularity through forward scatter (FSC) and side scatter (SSC) signals. Despite its widespread use, the…

Optics · Physics 2024-08-29 Jaepil Jo , Herve Hugonnet , Mahn Jae Lee , YongKeun Park

Recent crowd counting approaches have achieved excellent performance. However, they are essentially based on fully supervised paradigm and require large number of annotated samples. Obtaining annotations is an expensive and labour-intensive…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 Vishwanath A. Sindagi , Rajeev Yasarla , Deepak Sam Babu , R. Venkatesh Babu , Vishal M. Patel

It is increasingly common in many types of natural and physical systems (especially biological systems) to have different types of measurements performed on the same underlying system. In such settings, it is important to align the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Matthew Amodio , Smita Krishnaswamy

Current methods for sequence tagging, a core task in NLP, are data hungry, which motivates the use of crowdsourcing as a cheap way to obtain labelled data. However, annotators are often unreliable and current aggregation methods cannot…

Computation and Language · Computer Science 2019-09-09 Edwin Simpson , Iryna Gurevych

Multiplex brightfield imaging offers the advantage of simultaneously analyzing multiple biomarkers on a single slide, as opposed to single biomarker labeling on multiple consecutive slides. To accurately analyze multiple biomarkers…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Satarupa Mukherjee , Jim Martin , Yao Nie

The impact of machine learning (ML) in many fields of application is constrained by lack of annotated data. Among existing tools for ML-assisted data annotation, one little explored tool type relies on an analogy between the coordinates of…

Machine Learning · Computer Science 2023-05-25 Hannes Kath , Thiago S. Gouvêa , Daniel Sonntag

We propose a fully Bayesian framework for learning ground truth labels from noisy annotators. Our framework ensures scalability by factoring a generative, Bayesian soft clustering model over label distributions into the classic David and…

Artificial Intelligence · Computer Science 2021-06-22 Tharindu Cyril Weerasooriya , Alexander G. Ororbia , Christopher M. Homan

Accurate and fast extraction of lung volumes from computed tomography (CT) scans remains in a great demand in the clinical environment because the available methods fail to provide a generic solution due to wide anatomical variations of…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Awais Mansoor , Ulas Bagci , Brent Foster , Ziyue Xu , Deborah Douglas , Jeffrey M. Solomon , Jayaram K. Udupa , Daniel J. Mollura

Manually labeling datasets with object masks is extremely time consuming. In this work, we follow the idea of Polygon-RNN to produce polygonal annotations of objects interactively using humans-in-the-loop. We introduce several important…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 David Acuna , Huan Ling , Amlan Kar , Sanja Fidler

Generative models, such as GANs and diffusion models, have been used to augment training sets and boost performances in different tasks. We focus on generative models for cell detection instead, i.e., locating and classifying cells in given…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Chen Li , Xiaoling Hu , Shahira Abousamra , Meilong Xu , Chao Chen

This paper introduces a methodology for generating synthetic annotated data to address data scarcity in semantic segmentation tasks within the precision agriculture domain. Utilizing Denoising Diffusion Probabilistic Models (DDPMs) and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Andrew Heschl , Mauricio Murillo , Keyhan Najafian , Farhad Maleki

Quality assessment of agricultural produce is a crucial step in minimizing food stock wastage. However, this is currently done manually and often requires expert supervision, especially in smaller seeds like corn. We propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Sandeep Nagar , Prateek Pani , Raj Nair , Girish Varma

We present a novel graph neural network (GNN) approach for cell tracking in high-throughput microscopy videos. By modeling the entire time-lapse sequence as a direct graph where cell instances are represented by its nodes and their…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Tal Ben-Haim , Tammy Riklin Raviv

Large annotated datasets have been a key component in the success of deep learning. However, annotating medical images is challenging as it requires expertise and a large budget. In particular, annotating different types of cells in…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Cholmin Kang , Chunggi Lee , Heon Song , Minuk Ma , S ergio Pereira

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this…

Tissues and Organs · Quantitative Biology 2018-10-26 Stefan Engblom Daniel B. Wilson , Ruth E. Baker

High-quality annotated datasets are crucial for advancing machine learning in medical image analysis. However, a critical gap exists: most datasets either offer a single, clean ground truth, which hides real-world expert disagreement, or…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yonghao Si , Xingyuan Zeng , Zhao Chen , Libin Zheng , Caleb Chen Cao , Lei Chen , Jian Yin

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Synthetic data is becoming an increasingly promising technology, and successful applications can improve privacy, fairness, and data democratization. While there are many methods for generating synthetic tabular data, the task remains…

Machine Learning · Computer Science 2023-02-27 Alexander Norcliffe , Bogdan Cebere , Fergus Imrie , Pietro Lio , Mihaela van der Schaar

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang
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