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Background Clinical trials are essential to advancing cancer treatments, yet fewer than 10% of adults with cancer enroll in trials, and many studies fail to meet accrual targets. Artificial intelligence (AI) could improve identification of…

While deep learning models have become the predominant method for medical image segmentation, they are typically not capable of generalizing to unseen segmentation tasks involving new anatomies, image modalities, or labels. Given a new…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Victor Ion Butoi , Jose Javier Gonzalez Ortiz , Tianyu Ma , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Recent advances in data-centric medical AI have produced highly accurate diagnostic systems, but the emphasis on data curation and performance metrics has not translated into widespread clinical adoption. We conjecture that this limited…

Clinical research on smart health has an increasing demand for intelligent and clinic-oriented medical image computing algorithms and platforms that support various applications. To this end, we have developed SenseCare research platform,…

Human-Computer Interaction · Computer Science 2022-09-05 Qi Duan , Guotai Wang , Rui Wang , Chao Fu , Xinjun Li , Na Wang , Yechong Huang , Xiaodi Huang , Tao Song , Liang Zhao , Xinglong Liu , Qing Xia , Zhiqiang Hu , Yinan Chen , Shaoting Zhang

There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Chao Gou , Tianyu Shen , Wenbo Zheng , Huadan Xue , Hui Yu , Qiang Ji , Zhengyu Jin , Fei-Yue Wang

Human intelligence naturally intertwines omni-modal perception -- spanning vision, audio, and language -- with complex reasoning and tool usage to interact with the world. However, current multi-modal LLMs are primarily confined to bi-modal…

Artificial Intelligence · Computer Science 2026-03-03 Xiaoxi Li , Wenxiang Jiao , Jiarui Jin , Shijian Wang , Guanting Dong , Jiajie Jin , Hao Wang , Yinuo Wang , Ji-Rong Wen , Yuan Lu , Zhicheng Dou

Accessing high-quality, open-access dermatopathology image datasets for learning and cross-referencing is a common challenge for clinicians and dermatopathology trainees. To establish a comprehensive open-access dermatopathology dataset for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Ziyang Xu , Mingquan Lin , Yiliang Zhou , Zihan Xu , Seth J. Orlow , Shane A. Meehan , Alexandra Flamm , Ata S. Moshiri , Yifan Peng

We present Clinica (www.clinica.run), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. Clinica aims for researchers to i) spend less time on data management and processing, ii)…

Despite the growing scale of medical Vision-Language datasets, the impact of dataset quality on model performance remains under-explored. We introduce Open-PMC, a high-quality medical dataset from PubMed Central, containing 2.2 million…

We introduce DLSIA (Deep Learning for Scientific Image Analysis), a Python-based machine learning library that empowers scientists and researchers across diverse scientific domains with a range of customizable convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Eric J Roberts , Tanny Chavez , Alexander Hexemer , Petrus H. Zwart

A multitude of work has shown that machine learning-based medical diagnosis systems can be biased against certain subgroups of people. This has motivated a growing number of bias mitigation algorithms that aim to address fairness issues in…

Machine Learning · Computer Science 2023-02-21 Yongshuo Zong , Yongxin Yang , Timothy Hospedales

Transition from conventional to digital pathology requires a new category of biomedical informatic infrastructure which could facilitate delicate pathological routine. Pathological diagnoses are sensitive to many external factors and is…

Quantitative Methods · Quantitative Biology 2020-01-16 Pargorn Puttapirat , Haichuan Zhang , Jingyi Deng , Yuxin Dong , Jiangbo Shi , Hongyu He , Zeyu Gao , Chunbao Wang , Xiangrong Zhang , Chen Li

Federated learning has emerged as a compelling paradigm for medical image segmentation, particularly in light of increasing privacy concerns. However, most of the existing research relies on relatively stringent assumptions regarding the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Yangyang Xiang , Nannan Wu , Li Yu , Xin Yang , Kwang-Ting Cheng , Zengqiang Yan

MLE-Toolbox is a comprehensive open-source MATLAB toolbox for end-to-end analysis of magnetoencephalography (MEG) and electroencephalography (EEG) data. Inspired by widely used neuroimaging platforms such as Brainstorm and FieldTrip, it…

Neurons and Cognition · Quantitative Biology 2026-04-21 Xiaobo Liu

Artificial intelligence (AI) is showing promise in improving clinical diagnosis. In breast cancer screening, recent studies show that AI has the potential to improve early cancer diagnosis and reduce unnecessary workup. As the number of…

Recent advances in artificial intelligence research have led to a profusion of studies that apply deep learning to problems in image analysis and natural language processing among others. Additionally, the availability of open-source…

This article presents our steps to integrate complex and partly unstructured medical data into a clinical research database with subsequent decision support. Our main application is an integrated faceted search tool, accompanied by the…

Human-Computer Interaction · Computer Science 2018-10-31 Daniel Sonntag , Hans-Jürgen Profitlich

Medical image computing software is essential for identifying imaging biomarkers that can support diagnosis, prognosis, treatment planning, and clinical research. However, the lack of standardized, user-friendly, and reproducible software…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Mohammad Salmanpour , Mehrdad Oveisi , Isaac Shiri , Arman Rahmim

Open challenges have become the de facto standard for comparative ranking of medical AI methods. Despite their importance, medical AI leaderboards exhibit three persistent limitations: (1) score gaps are rarely tested for statistical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Ariel Lubonja , Pedro R. A. S. Bassi , Wenxuan Li , Hualin Qiao , Randal Burns , Alan L. Yuille , Zongwei Zhou

Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer