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Molecular representation learning methods typically tokenize molecules as individual atoms or use rigid, rule-based fragment decompositions, limiting their ability to capture meaningful chemical substructure context. We introduce…

Machine Learning · Computer Science 2026-05-26 Ankur Samanta , Rohan Gupta , Aditi Misra , Christian McIntosh Clarke , Jayakumar Rajadas

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Graph deep learning has recently emerged as a powerful ML concept allowing to generalize successful deep neural architectures to non-Euclidean structured data. Such methods have shown promising results on a broad spectrum of applications…

Machine Learning · Computer Science 2022-05-16 Anees Kazi , Luca Cosmo , Seyed-Ahmad Ahmadi , Nassir Navab , Michael Bronstein

Graphs are typical non-Euclidean data of complex structures. In recent years, Riemannian graph representation learning has emerged as an exciting alternative to Euclidean ones. However, Riemannian methods are still in an early stage: most…

Machine Learning · Computer Science 2024-01-03 Li Sun , Zhenhao Huang , Zixi Wang , Feiyang Wang , Hao Peng , Philip Yu

Graph convolutional network (GCN) is generalization of convolutional neural network (CNN) to work with arbitrarily structured graphs. A binary adjacency matrix is commonly used in training a GCN. Recently, the attention mechanism allows the…

Machine Learning · Statistics 2022-03-03 Chao Shang , Qinqing Liu , Ko-Shin Chen , Jiangwen Sun , Jin Lu , Jinfeng Yi , Jinbo Bi

The prediction of physicochemical properties from molecular structures is a crucial task for artificial intelligence aided molecular design. A growing number of Graph Neural Networks (GNNs) have been proposed to address this challenge.…

Machine Learning · Computer Science 2020-11-17 Shuo Zhang , Yang Liu , Lei Xie

Generating text from graph-based data, such as Abstract Meaning Representation (AMR), is a challenging task due to the inherent difficulty in how to properly encode the structure of a graph with labeled edges. To address this difficulty, we…

Computation and Language · Computer Science 2019-09-04 Leonardo F. R. Ribeiro , Claire Gardent , Iryna Gurevych

Graph Neural Networks (GNNs) have shown remarkable success in molecular tasks, yet their interpretability remains challenging. Traditional model-level explanation methods like XGNN and GNNInterpreter often fail to identify valid…

Machine Learning · Computer Science 2025-04-25 Zhaoning Yu , Hongyang Gao

Graph Convolutional Networks (GCNs) are powerful models for node representation learning tasks. However, the node representation in existing GCN models is usually generated by performing recursive neighborhood aggregation across multiple…

Machine Learning · Computer Science 2021-05-11 Hao Chen , Zengde Deng , Yue Xu , Zhoujun Li

Graph generation techniques are increasingly being adopted for drug discovery. Previous graph generation approaches have utilized relatively small molecular building blocks such as atoms or simple cycles, limiting their effectiveness to…

Machine Learning · Computer Science 2020-04-21 Wengong Jin , Regina Barzilay , Tommi Jaakkola

The decoupled Graph Convolutional Network (GCN), a recent development of GCN that decouples the neighborhood aggregation and feature transformation in each convolutional layer, has shown promising performance for graph representation…

Machine Learning · Computer Science 2022-11-16 Jinsong Chen , Boyu Li , Kun He

Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou

Deep learning on graphs and in particular, graph convolutional neural networks, have recently attracted significant attention in the machine learning community. Many of such techniques explore the analogy between the graph Laplacian…

Machine Learning · Computer Science 2018-02-07 Federico Monti , Karl Otness , Michael M. Bronstein

Artificial neural networks show promising performance in detecting correlations within data that are associated with specific outcomes. However, the black-box nature of such models can hinder the knowledge advancement in research fields by…

Machine Learning · Computer Science 2023-10-09 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Molecular representation learning contributes to multiple downstream tasks such as molecular property prediction and drug design. To properly represent molecules, graph contrastive learning is a promising paradigm as it utilizes…

Machine Learning · Computer Science 2022-03-14 Yin Fang , Qiang Zhang , Haihong Yang , Xiang Zhuang , Shumin Deng , Wen Zhang , Ming Qin , Zhuo Chen , Xiaohui Fan , Huajun Chen

Drug Discovery is a fundamental and ever-evolving field of research. The design of new candidate molecules requires large amounts of time and money, and computational methods are being increasingly employed to cut these costs. Machine…

Machine Learning · Statistics 2021-05-28 Pietro Bongini , Monica Bianchini , Franco Scarselli

We investigate the problem of producing structured graph representations of visual scenes. Our work analyzes the role of motifs: regularly appearing substructures in scene graphs. We present new quantitative insights on such repeated…

Computer Vision and Pattern Recognition · Computer Science 2018-03-30 Rowan Zellers , Mark Yatskar , Sam Thomson , Yejin Choi

Numerous important problems can be framed as learning from graph data. We propose a framework for learning convolutional neural networks for arbitrary graphs. These graphs may be undirected, directed, and with both discrete and continuous…

Machine Learning · Computer Science 2016-06-09 Mathias Niepert , Mohamed Ahmed , Konstantin Kutzkov

In recent years, deep learning has achieved remarkable success in the field of image restoration. However, most convolutional neural network-based methods typically focus on a single scale, neglecting the incorporation of multi-scale…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Jiatao Jiang , Zhen Cui , Chunyan Xu , Jian Yang

Dense regions in networks are an indicator of interesting and unusual information. However, most existing methods only consider simple, undirected, unweighted networks. Complex networks in the real-world often have rich information though:…

Social and Information Networks · Computer Science 2021-03-08 Ahmet Erdem Sariyuce