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Multiple Instance Learning (MIL) is a weak supervision learning paradigm that allows modeling of machine learning problems in which labels are available only for groups of examples called bags. A positive bag may contain one or more…

Machine Learning · Computer Science 2019-10-29 Amina Asif , Fayyaz ul Amir Afsar Minhas

The favorable performance of Vision Transformers (ViTs) is often attributed to the multi-head self-attention (MSA). The MSA enables global interactions at each layer of a ViT model, which is a contrasting feature against Convolutional…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Nam Hyeon-Woo , Kim Yu-Ji , Byeongho Heo , Dongyoon Han , Seong Joon Oh , Tae-Hyun Oh

Cervical cancer is a crucial global health concern for women, and the persistent infection of High-risk HPV mainly triggers this remains a global health challenge, with young women diagnosis rates soaring from 10\% to 40\% over three…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Tatsuhiro Baba , Abu Saleh Musa Miah , Jungpil Shin , Md. Al Mehedi Hasan

In this paper, we focus on the challenging multicategory instance segmentation problem in remote sensing images (RSIs), which aims at predicting the categories of all instances and localizing them with pixel-level masks. Although many…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Tianyang Zhang , Xiangrong Zhang , Peng Zhu , Xu Tang , Chen Li , Licheng Jiao , Huiyu Zhou

Accurate segmentation of organelle instances from electron microscopy (EM) images plays an essential role in many neuroscience researches. However, practical scenarios usually suffer from high annotation costs, label scarcity, and large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Dafei Qiu , Shan Xiong , Jiajin Yi , Jialin Peng

Diagnosis and treatment of multiple pulmonary nodules are clinically important but challenging. Prior studies on nodule characterization use solitary-nodule approaches on multiple nodular patients, which ignores the relations between…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Jiancheng Yang , Haoran Deng , Xiaoyang Huang , Bingbing Ni , Yi Xu

The advancements in deep learning technologies have produced immense contributions to biomedical image analysis applications. With breast cancer being the common deadliest disease among women, early detection is the key means to improve…

Image and Video Processing · Electrical Eng. & Systems 2022-02-04 Narinder Singh Punn , Sonali Agarwal

Accurate characterisation of visual attributes such as spiculation, lobulation, and calcification of lung nodules is critical in cancer management. The characterisation of these attributes is often subjective, which may lead to high inter-…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Multiple instance learning (MIL) is a powerful approach to classify whole slide images (WSIs) for diagnostic pathology. A fundamental challenge of MIL on WSI classification is to discover the \textit{critical instances} that trigger the bag…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Zhikang Wang , Yue Bi , Tong Pan , Xiaoyu Wang , Chris Bain , Richard Bassed , Seiya Imoto , Jianhua Yao , Jiangning Song

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current…

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Extracting associations that recur across multiple studies while controlling the false discovery rate is a fundamental challenge. Here, we consider an extension of Efron's single-study two-groups model to allow joint analysis of multiple…

Methodology · Statistics 2019-01-14 David Amar , Ron Shamir , Daniel Yekutieli

Long-term memory is a cornerstone of human intelligence. Enabling AI to process lifetime-scale information remains a long-standing pursuit in the field. Due to the constraints of full-attention architectures, the effective context length of…

Computation and Language · Computer Science 2026-04-14 Yu Chen , Runkai Chen , Sheng Yi , Xinda Zhao , Xiaohong Li , Jianjin Zhang , Jun Sun , Chuanrui Hu , Yunyun Han , Lidong Bing , Yafeng Deng , Tianqiao Chen

Attention-based learning for fine-grained image recognition remains a challenging task, where most of the existing methods treat each object part in isolation, while neglecting the correlations among them. In addition, the multi-stage or…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Ming Sun , Yuchen Yuan , Feng Zhou , Errui Ding

Motivated by cutting-edge applications like cryo-electron microscopy (cryo-EM), the Multi-Reference Alignment (MRA) model entails the learning of an unknown signal from repeated measurements of its images under the latent action of a group…

Statistics Theory · Mathematics 2022-03-11 Subhro Ghosh , Philippe Rigollet

Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

Segmenting medical images accurately and reliably is important for disease diagnosis and treatment. It is a challenging task because of the wide variety of objects' sizes, shapes, and scanning modalities. Recently, many convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Ange Lou , Shuyue Guan , Murray Loew

Pathological complete response (pCR) is a key prognostic factor in breast cancer patients undergoing neoadjuvant therapy, strongly associated with long-term survival and treatment personalization. However, accurate pre-treatment pCR…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Alice Natalina Caragliano , Valerio Guarrasi , Michela Gravina , Carlo Sansone , Paolo Soda