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Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

We propose Low-Rank Sparse Attention (Lorsa), a sparse replacement model of Transformer attention layers to disentangle original Multi Head Self Attention (MHSA) into individually comprehensible components. Lorsa is designed to address the…

Machine Learning · Computer Science 2025-04-30 Zhengfu He , Junxuan Wang , Rui Lin , Xuyang Ge , Wentao Shu , Qiong Tang , Junping Zhang , Xipeng Qiu

Although deep convolutional networks have been widely studied for head and neck (HN) organs at risk (OAR) segmentation, their use for routine clinical treatment planning is limited by a lack of robustness to imaging artifacts, low soft…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Harini Veeraraghavan , Jue Jiang , Sharif Elguindi , Sean L. Berry , Ifeanyirochukwu Onochie , Aditya Apte , Laura Cervino , Joseph O. Deasy

Brain tumor is the most common and deadliest disease that can be found in all age groups. Generally, MRI modality is adopted for identifying and diagnosing tumors by the radiologists. The correct identification of tumor regions and its type…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Sachin Gupta , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

Recent advances in deep learning have enabled the development of automated frameworks for analysing medical images and signals, including analysis of cervical cancer. Many previous works focus on the analysis of isolated cervical cells, or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Ruiqi Wang , Mohammad Ali Armin , Simon Denman , Lars Petersson , David Ahmedt-Aristizabal

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yuxiang Luo , Qing Xu , Hai Huang , Yuqi Ouyang , Zhen Chen , Wenting Duan

Accurate cancer diagnosis remains a critical challenge in digital pathology, largely due to the gigapixel size and complex spatial relationships present in whole slide images. Traditional multiple instance learning (MIL) methods often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Kechun Liu , Wenjun Wu , Joann G. Elmore , Linda G. Shapiro

We propose a novel semi-supervised image segmentation method that simultaneously optimizes a supervised segmentation and an unsupervised reconstruction objectives. The reconstruction objective uses an attention mechanism that separates the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Shuai Chen , Gerda Bortsova , Antonio Garcia-Uceda Juarez , Gijs van Tulder , Marleen de Bruijne

Fine-grained classification of microscopic image data with limited samples is an open problem in computer vision and biomedical imaging. Deep learning based vision systems mostly deal with high number of low-resolution images, whereas…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Mengran Fan , Tapabrata Chakrabort , Eric I-Chao Chang , Yan Xu , Jens Rittscher

Bladder cancer is one of the most prevalent malignancies worldwide, with a recurrence rate of up to 78%, necessitating accurate post-operative monitoring for effective patient management. Multi-sequence contrast-enhanced MRI is commonly…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xueyang Li , Zongren Wang , Yuliang Zhang , Zixuan Pan , Yu-Jen Chen , Nishchal Sapkota , Gelei Xu , Danny Z. Chen , Yiyu Shi

Recently neural networks and multiple instance learning are both attractive topics in Artificial Intelligence related research fields. Deep neural networks have achieved great success in supervised learning problems, and multiple instance…

Machine Learning · Statistics 2020-04-08 Xinggang Wang , Yongluan Yan , Peng Tang , Xiang Bai , Wenyu Liu

We introduce the Poisson Log-Normal Graphical Model for count data, and present a normality transformation for data arising from this distribution. The model and transformation are feasible for high-throughput microRNA (miRNA) sequencing…

Computation · Statistics 2017-08-16 David Sinclair , Giles Hooker

miRNA and gene expression profiles have been proved useful for classifying cancer samples. Efficient classifiers have been recently sought and developed. A number of attempts to classify cancer samples using miRNA/gene expression profiles…

Computational Engineering, Finance, and Science · Computer Science 2014-01-21 Rania Ibrahim , Noha A. Yousri , Mohamed A. Ismail , Nagwa M. El-Makky

Brain tumor represents one of the most fatal cancers around the world, and is very common in children and the elderly. Accurate identification of the type and grade of tumor in the early stages plays an important role in choosing a precise…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Dunyuan Xu , Xi Wang , Jinyue Cai , Pheng-Ann Heng

DeepSeek Sparse Attention (DSA) sets the state of the art for fine-grained inference-time sparse attention by introducing a learned token-wise indexer that scores every prefix token and selects the most relevant ones for the main attention.…

Machine Learning · Computer Science 2026-05-11 Ruijie Zhou , Fanxu Meng , Yufei Xu , Tongxuan Liu , Guangming Lu , Muhan Zhang , Wenjie Pei

Attention is typically used to select informative sub-phrases that are used for prediction. This paper investigates the novel use of attention as a form of feature augmentation, i.e, casted attention. We propose Multi-Cast Attention…

Computation and Language · Computer Science 2018-06-05 Yi Tay , Luu Anh Tuan , Siu Cheung Hui

Attention mechanisms are often used in deep neural networks for distantly supervised relation extraction (DS-RE) to distinguish valid from noisy instances. However, traditional 1-D vector attention models are insufficient for the learning…

Computation and Language · Computer Science 2018-09-05 Jinhua Du , Jingguang Han , Andy Way , Dadong Wan

Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Jiawen Yao , Xinliang Zhu , Jitendra Jonnagaddala , Nicholas Hawkins , Junzhou Huang

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso
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