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Advances in chip-scale photonic-electronic integration are enabling a new generation of foundry-manufacturable implantable silicon neural probes incorporating nanophotonic waveguides and microelectrodes for optogenetic stimulation and…
Second-harmonic generation allows for coherently bridging distant regions of the optical spectrum, with applications ranging from laser technology to self-referencing of frequency combs. However, accessing the nonlinear response of a medium…
Viscous streaming refers to the rectified, steady flows that emerge when a liquid oscillates around an immersed microfeature, typically a solid body or a bubble. The ability of such features to locally concentrate stresses produces strong…
Molecular Communications (MC), transferring information via chemical signals, holds promise for transformative healthcare applications within the Internet of Bio-Nano Things (IoBNT) framework. Despite promising advances toward practical MC…
Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…
We develop an electrokinetic technique that continuously manipulates colloidal particles to concentrate into patterned particulate groups in an energy efficient way, by exclusive harnessing of the intrinsic Joule heating effects. Our…
Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and…
Flows enabled by phoretic mechanisms are of significant interest in several biological and biomedical processes, such as bacterial motion and targeted drug delivery. Here, we develop a homogenization-based macroscopic boundary condition…
This fluid dynamics video showcases how optically induced electrowetting can be used to manipulate liquid droplets in open space and particulate phases inside the droplet. A photoconductive layer is added to a conventional…
Acoustic streaming can be generated around sharp structures, even when the acoustic wavelength is much larger than the vessel size. This sharp-edge streaming can be relatively intense, \textcolor{blue}{owing to the strongly focused inertial…
The advent in recent years of highly parallelized microfluidic chemical reaction systems necessitates an understanding of all fluid dynamic time scales including the often neglected millisecond time scale of the inertia of the liquid. We…
We have developed and characterized two novel micro flow sensors based on measuring the electrical impedance of the interface between the flowing liquid and metallic electrodes embedded on the channel walls. These flow sensors are very…
The design of strategies to generate efficient mixing is crucial for a variety of applications, particularly digital microfluidic devices that use small "discrete" fluid volumes (droplets) as fluid carriers and microreactors. In recent…
Nanoscale single-electron pumps can be used to generate accurate currents, and can potentially serve to realize a new standard of electrical current based on elementary charge. Here, we use a silicon-based quantum dot with tunable tunnel…
The ability to induce regions of high and low ionic concentration adjacent to a permeselective membrane or nanochannel subject to an externally applied electric field (a phenomenon termed concentration-polarization) has been used for a…
Microfluidic systems with integrated sensors are ideal platforms to study and emulate processes such as complex multiphase flow and reactive transport in porous media, numerical modeling of bulk systems in medicine, and in engineering.…
Active emulsions can spontaneously form self-propelled droplets or phoretic micropumps. It has been predicted that the interaction with their self-generated chemical fields can lead to multistable higher-order flows and chemodynamic…
Contactless manipulation of small objects is essential for biomedical and chemical applications, such as cell analysis, assisted fertilisation, and precision chemistry. Established methods, including optical, acoustic, and magnetic…
We experimentally demonstrate hyperfine optical pumping of rubidium atoms probed by an evanescent electromagnetic field at a dielectric-vapor interface. This light-atom interaction at the nanoscale is investigated using a right angle prism…
Confocal Raman microscopy offers a particular pathway for monitoring chemical "fingerprints" of intracellular components like the cell membrane, organelles, and nucleus. Nevertheless, conventional Raman acquisitions of fixed or randomly…