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Deep neural networks are powerful tools for biomedical image segmentation. These models are often trained with heavy supervision, relying on pairs of images and corresponding voxel-level labels. However, obtaining segmentations of…

Interactive video segmentation often requires many user interventions for robust performance in challenging scenarios (e.g., occlusions, object separations, camouflage, etc.). Yet, even state-of-the-art models like SAM2 use corrections only…

Brain lesion and anatomy segmentation in magnetic resonance images are fundamental tasks in neuroimaging research and clinical practice. Given enough training data, convolutional neuronal networks (CNN) proved to outperform all existent…

Variational Level Set (VLS) has been a widely used method in medical segmentation. However, segmentation accuracy in the VLS method dramatically decreases when dealing with intervening factors such as lighting, shadows, colors, etc.…

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion…

Adversarial training has been demonstrated to be the most effective approach to defend against adversarial attacks. However, existing adversarial training methods show apparent oscillations and overfitting issue in the training process,…

Automatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. We propose a multi-modal multi-path convolutional neural network…

We introduce MHVAE, a deep hierarchical variational auto-encoder (VAE) that synthesizes missing images from various modalities. Extending multi-modal VAEs with a hierarchical latent structure, we introduce a probabilistic formulation for…

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent…

Visual data can be understood at different levels of granularity, where global features correspond to semantic-level information and local features correspond to texture patterns. In this work, we propose a framework, called SPLIT, which…

Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus that affects pediatric patients with significantly greater severity and worse renal outcomes compared to adults. Despite the urgent clinical need, predicting…

Efficient and accurate whole-brain lesion segmentation remains a challenge in medical image analysis. In this work, we revisit MeshNet, a parameter-efficient segmentation model, and introduce a novel multi-scale dilation pattern with an…

The development of artificial intelligence models for macular edema (ME) analy-sis always relies on expert-annotated pixel-level image datasets which are expen-sive to collect prospectively. While anomaly-detection-based weakly-supervised…

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Pseudo-normality synthesis, which computationally generates a pseudo-normal image from an abnormal one (e.g., with lesions), is critical in many perspectives, from lesion detection, data augmentation to clinical surgery suggestion. However,…

The most recent fast and accurate image segmentation methods are built upon fully convolutional deep neural networks. In this paper, we propose new deep learning strategies for DenseNets to improve segmenting images with subtle differences…

Objective: Ultrasound Shear Wave Elastography (SWE) demonstrates great potential in assessing soft-tissue pathology by mapping tissue stiffness, which is linked to malignancy. Traditional SWE methods have shown promise in estimating tissue…

Deep learning models in medical contexts face challenges like data scarcity, inhomogeneity, and privacy concerns. This study focuses on improving ventricular segmentation in brain MRI images using synthetic data. We employed two latent…

Estimation of individualized treatment effects (ITE) from observational studies is a fundamental problem in causal inference and holds significant importance across domains, including healthcare. However, limited observational datasets pose…

We present MedicDeepLabv3+, a convolutional neural network that is the first completely automatic method to segment cerebral hemispheres in magnetic resonance (MR) volumes of rats with lesions. MedicDeepLabv3+ improves the state-of-the-art…