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The paper utilizes the graph embeddings generated for entities of a large biomedical database to perform link prediction to capture various new relationships among different entities. A novel node similarity measure is proposed that…

Information Retrieval · Computer Science 2021-11-01 Prakhar Gurawa , Matthias Nickles

Knowledge Graphs are a widely used method to represent relations between entities in various AI applications, and Graph Embedding has rapidly become a standard technique to represent Knowledge Graphs in such a way as to facilitate…

Machine Learning · Computer Science 2023-11-02 Zhijin Guo , Zhaozhen Xu , Martha Lewis , Nello Cristianini

We explore the task of recognizing peoples' identities in photo albums in an unconstrained setting. To facilitate this, we introduce the new People In Photo Albums (PIPA) dataset, consisting of over 60000 instances of 2000 individuals…

Computer Vision and Pattern Recognition · Computer Science 2015-02-02 Ning Zhang , Manohar Paluri , Yaniv Taigman , Rob Fergus , Lubomir Bourdev

Embedding methods have demonstrated robust performance on the task of link prediction in knowledge graphs, by mostly encoding entity relationships. Recent methods propose to enhance the loss function with a literal-aware term. In this…

Artificial Intelligence · Computer Science 2022-04-26 Jiang Wang , Filip Ilievski , Pedro Szekely , Ke-Thia Yao

Knowledge graph embedding, which projects symbolic entities and relations into continuous vector spaces, is gaining increasing attention. Previous methods allow a single static embedding for each entity or relation, ignoring their intrinsic…

Artificial Intelligence · Computer Science 2020-04-07 Quan Wang , Pingping Huang , Haifeng Wang , Songtai Dai , Wenbin Jiang , Jing Liu , Yajuan Lyu , Yong Zhu , Hua Wu

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Knowledge-based visual question answering (VQA) involves answering questions that require external knowledge not present in the image. Existing methods first retrieve knowledge from external resources, then reason over the selected…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Zhengyuan Yang , Zhe Gan , Jianfeng Wang , Xiaowei Hu , Yumao Lu , Zicheng Liu , Lijuan Wang

Graph embedding learning that aims to automatically learn low-dimensional node representations, has drawn increasing attention in recent years. To date, most recent graph embedding methods are evaluated on social and information networks…

The standard approach for visual place recognition is to use global image descriptors to retrieve the most similar database images for a given query image. The results can then be further improved with re-ranking methods that re-order the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Gustav Hanning , Gabrielle Flood , Viktor Larsson

Pain is a complex concept that can interconnect with other concepts such as a disorder that might cause pain, a medication that might relieve pain, and so on. To fully understand the context of pain experienced by either an individual or…

Machine Learning · Computer Science 2023-08-21 Jaya Chaturvedi , Tao Wang , Sumithra Velupillai , Robert Stewart , Angus Roberts

Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…

Machine Learning · Computer Science 2024-06-13 Ahmad Wisnu Mulyadi , Heung-Il Suk

Drug repositioning-a promising strategy for discovering new therapeutic uses for existing drugs-has been increasingly explored in the computational science literature using biomedical databases. However, the technological potential of drug…

Artificial Intelligence · Computer Science 2024-07-25 Yongseung Jegal , Jaewoong Choi , Jiho Lee , Ki-Su Park , Seyoung Lee , Janghyeok Yoon

Learning medical visual representations from image-report pairs through joint learning has garnered increasing research attention due to its potential to alleviate the data scarcity problem in the medical domain. The primary challenges stem…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jun Wang , Lixing Zhu , Xiaohan Yu , Abhir Bhalerao , Yulan He

Predicting the interaction between a compound and a target is crucial for rapid drug repurposing. Deep learning has been successfully applied in drug-target affinity (DTA) problem. However, previous deep learning-based methods ignore…

Machine Learning · Computer Science 2020-09-29 Tri Minh Nguyen , Thin Nguyen , Thao Minh Le , Truyen Tran

A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

Machine Learning · Computer Science 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Prediction of protein-ligand interactions (PLI) plays a crucial role in drug discovery as it guides the identification and optimization of molecules that effectively bind to target proteins. Despite remarkable advances in deep…

Biomolecules · Quantitative Biology 2023-07-18 Seokhyun Moon , Sang-Yeon Hwang , Jaechang Lim , Woo Youn Kim

Blind image quality assessment (BIQA) aims to predict perceptual image quality scores without access to reference images. State-of-the-art BIQA methods typically require subjects to score a large number of images to train a robust model.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Fei Gao , Dacheng Tao , Xinbo Gao , Xuelong Li

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Face recognition is the very significant field in pattern recognition area. It has multiple applications in military and finance, to name a few. In this paper, the combination of the sparse PCA with the nearest-neighbor method (and with the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-02 Loc Hoang Tran , Tuan Tran , An Mai

Pharmacovigilance and clinical decision support systems utilize structured drug safety data to guide medical practice. However, existing datasets frequently depend on terminologies such as MedDRA, which limits their semantic reasoning…

Information Retrieval · Computer Science 2026-02-24 Mohammad Ashhad , Olga Mashkova , Ricardo Henao , Robert Hoehndorf