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We investigated the beat-to-beat fluctuation of the photoplethysmography (PPG) waveform. The motivation is that morphology variability extracted from the arterial blood pressure (ABP) has been found to correlate with baseline condition and…

Quantitative Methods · Quantitative Biology 2025-03-20 Yu-Chieh Ho , Te-Sheng Lin , She-Chih Wang , Chen-Shi Chang , Yu-Ting Lin

Arterial pulse waves contain clinically useful information: their intensity varies with cardiac performance, their speed (pulse wave velocity; PWV) depends on arterial stiffness and their reflection is affected by conduit artery tone. Here…

Medical Physics · Physics 2022-05-31 Ethan M Rowland , Kai Riemer , Kevin Lichtenstein , Mengxing Tang , Peter Weinberg

Much of the information of breathing is contained within the photoplethysmography (PPG) signal, through changes in venous blood flow, heart rate and stroke volume. We aim to leverage this fact, by employing a novel deep learning framework…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Harry J. Davies , Danilo P. Mandic

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

Fluid Dynamics · Physics 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…

Medical Physics · Physics 2021-10-22 Alex Ce Zhang , Yu-Hwa Lo

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are an effective tool for studying cardiac function and disease, and hold promise for screening drug effects on human tissue. Changes to motion patterns in these cells…

Tissues and Organs · Quantitative Biology 2024-07-09 Henrik Finsberg , Verena Charwat , Kevin Healy , Samuel Wall

A manual measurement of blood vessels diameter is a conventional component of routine visual assessment of microcirculation, say, during optical capillaroscopy. However, many modern optical methods for blood flow measurements demand the…

Quantitative Methods · Quantitative Biology 2017-04-21 Eugene B. Postnikov , Maria O. Tsoy , Maxim A. Kurochkin , Dmitry E. Postnov

In living organisms, the natural motion caused by the heartbeat, breathing, or muscle movements leads to the deformation of tissue caused by translation and stretching of the tissue structure. This effect results in the displacement or…

Objective: Arterial stiffness is an important marker to predict cardio vascular events. Common measurement techniques to determine the condition of the aorta are limited to the acquisition of the arterial pulse wave at the extremities. The…

Medical Physics · Physics 2019-03-06 Roman Kusche , Arthur-Vincent Lindenberg , Sebastian Hauschild , Martin Ryschka

This article presents an algorithm for the evaluation of organelles' movements inside of an unmodified live cell. We used a time-lapse image series obtained using wide-field bright-field photon transmission microscopy as an algorithm input.…

Quantitative Methods · Quantitative Biology 2016-12-14 Renata Rychtarikova , Dalibor Stys

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree, including the cerebral arteries, bifurcations and intracranial aneurysms. This model intends to provide a substantial dataset of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Goal: A new method for heart rate monitoring using photoplethysmography (PPG) during physical activities is proposed. Methods: It jointly estimates spectra of PPG signals and simultaneous acceleration signals, utilizing the multiple…

Other Computer Science · Computer Science 2015-07-22 Zhilin Zhang

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow…

Tissues and Organs · Quantitative Biology 2020-06-05 Nam Lyong Kang

We suggest a low cost, non invasive healthcare system that measures haemoglobin levels in patients and can be used as a preliminary diagnostic test for anaemia. A combination of image processing, machine learning and deep learning…

Machine Learning · Computer Science 2020-12-01 Sarah , S. Sidhartha Narayan , Irfaan Arif , Hrithwik Shalu , Juned Kadiwala

The morphology and velocity of the pulse wave in the arteries provide meaningful information about the cardiovascular system. Nowadays, the pulse wave is usually acquired using common blood pressure cuffs at the extremities. This work…

Medical Physics · Physics 2019-03-01 Roman Kusche , Turner Adornetto , Paula Klimach , Martin Ryschka

Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…

Quantitative Methods · Quantitative Biology 2020-02-21 Megan J. Chambers , Mitchel J. Colebank , M Umar Qureshi , Rachel Clipp , Mette S. Olufsen

Many applications in aerodynamics, particularly in closed-loop control, depend on sensors to estimate the evolving state of the flow. This estimation task is inherently accompanied by uncertainty due to the noisy measurements of sensors or…

Fluid Dynamics · Physics 2026-01-07 Jeff D. Eldredge , Hanieh Mousavi

Photoplethysmography (PPG) is a method of detecting variation in blood volume commonly through contact with the skin and involving the usage of one or multiple sensors. PPG is typically used in health-related fields and one of its most…

Medical Physics · Physics 2021-08-24 Jiesheng He , Wei Wu