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Insufficient performance of optimization approaches for fitting of mathematical models is still a major bottleneck in systems biology. In this manuscript, the reasons and methodological challenges are summarized as well as their impact in…

Performance · Computer Science 2019-07-09 Clemens Kreutz

I present a critique of the methods used in a typical paper. This leads to three broad conclusions about the conventional use of statistical methods. First, results are often reported in an unnecessarily obscure manner. Second, the null…

Applications · Statistics 2013-03-05 Michael Wood

The study of associations and their causal explanations is a central research activity whose methodology varies tremendously across fields. Even within specialized subfields, comparisons across textbooks and journals reveals that the basics…

Methodology · Statistics 2025-10-13 Sander Greenland

A randomized trial and an analysis of observational data designed to emulate the trial sample observations separately, but have the same eligibility criteria, collect information on some shared baseline covariates, and compare the effects…

Methodology · Statistics 2022-03-29 Issa J. Dahabreh , Jon A. Steingrimsson , James M. Robins , Miguel A. Hernán

Assessments such as standardized tests and teacher evaluations of students' classroom participation are central elements of most educational systems. Assessments inform the student, parent, teacher, and school about the student learning…

General Economics · Economics 2022-08-12 Hans Henrik Sievertsen

Effective summarisation evaluation metrics enable researchers and practitioners to compare different summarisation systems efficiently. Estimating the effectiveness of an automatic evaluation metric, termed meta-evaluation, is a critically…

Computation and Language · Computer Science 2024-10-01 Xiang Dai , Sarvnaz Karimi , Biaoyan Fang

Benchmarking, which involves collecting reference datasets and demonstrating method performances, is a requirement for the development of new computational tools, but also becomes a domain of its own to achieve neutral comparisons of…

Other Quantitative Biology · Quantitative Biology 2025-07-24 Izaskun Mallona , Charlotte Soneson , Ben Carrillo , Almut Luetge , Daniel Incicau , Reto Gerber , Anthony Sonrel , Mark D. Robinson

Simulation-based inference plays a major role in modern statistics, and often employs either reallocating (as in a randomization test) or resampling (as in bootstrapping). Reallocating mimics random allocation to treatment groups, while…

Statistics Theory · Mathematics 2017-08-08 Kari Lock Morgan

Recommender systems have generated tremendous value for both users and businesses, drawing significant attention from academia and industry alike. However, due to practical constraints, academic research remains largely confined to offline…

Information Retrieval · Computer Science 2025-09-09 Kuan Zou , Aixin Sun

Scientific knowledge expands by observing the world, hypothesizing some theories about it, and testing them against collected data. When those theories take the form of statistical models, statistical analyses are involved in the process of…

Machine Learning · Statistics 2026-03-11 Arnaud Delaunoy

This paper highlights the need to bring document classification benchmarking closer to real-world applications, both in the nature of data tested ($X$: multi-channel, multi-paged, multi-industry; $Y$: class distributions and label set…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Jordy Van Landeghem , Sanket Biswas , Matthew B. Blaschko , Marie-Francine Moens

The chapter supports educators and postgraduate students in understanding the role of simulation in software engineering research based on the authors' experience. This way, it includes a background positioning simulation-based studies in…

Software Engineering · Computer Science 2025-01-10 Breno Bernard Nicolau de França , Dietmar Pfahl , Valdemar Vicente Graciano Neto , Nauman bin Ali

Experimental evaluation is an integral part in the design process of algorithms. Publicly available benchmark instances are widely used to evaluate methods in SAT solving. For the interpretation of results and the design of algorithm…

Artificial Intelligence · Computer Science 2021-09-10 Markus Iser , Luca Springer , Carsten Sinz

In modern applications, statisticians are faced with integrating heterogeneous data modalities relevant for an inference, prediction, or decision problem. In such circumstances, it is convenient to use a graphical model to represent the…

Methodology · Statistics 2017-08-30 Pierre E. Jacob , Lawrence M. Murray , Chris C. Holmes , Christian P. Robert

Many major works in social science employ matching to make causal conclusions, but different matches on the same data may produce different treatment effect estimates, even when they achieve similar balance or minimize the same loss…

Applications · Statistics 2023-03-23 Marco Morucci , Cynthia Rudin

In the era of big data, analysts usually explore various statistical models or machine learning methods for observed data in order to facilitate scientific discoveries or gain predictive power. Whatever data and fitting procedures are…

Machine Learning · Statistics 2018-10-24 Jie Ding , Vahid Tarokh , Yuhong Yang

Benchmarking has driven scientific progress in Evolutionary Computation, yet current practices fall short of real-world needs. Widely used synthetic suites such as BBOB and CEC isolate algorithmic phenomena but poorly reflect the structure,…

Predictive benchmarking, the evaluation of machine learning models based on predictive performance and competitive ranking, is a central epistemic practice in machine learning research and an increasingly prominent method for scientific…

Machine Learning · Computer Science 2025-10-28 Timo Freiesleben , Sebastian Zezulka

Collaborative competitions have gained popularity in the scientific and technological fields. These competitions involve defining tasks, selecting evaluation scores, and devising result verification methods. In the standard scenario,…

Machine Learning · Computer Science 2024-08-22 Sergio Nava-Muñoz , Mario Graff , Hugo Jair Escalante

There are many atomistic simulation methods with very different costs, accuracies, transferabilities, and numbers of empirical parameters. I show how statistical model selection can compare these methods fairly, even when they are very…

Chemical Physics · Physics 2025-10-07 Jonathan E. Moussa