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A discrete-event simulation (DES) involves the execution of a sequence of event handlers dynamically scheduled at runtime. As a consequence, a priori knowledge of the control flow of the overall simulation program is limited. In particular,…

Performance · Computer Science 2018-05-14 Marc Leinweber , Hannes Hartenstein , Philipp Andelfinger

Datacenters are the backbone of our digital society, but raise numerous operational challenges. We envision digital twins becoming primary instruments in datacenter operations, continuously and autonomously helping with major operational…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Radu Nicolae , Jules van der Toorn , Stavriana Kraniti , Houcen Liu , Alexandru Iosup

Nowadays there is a large availability of discrete event simulation software that can be easily used in different domains: from industry to supply chain, from healthcare to business management, from training to complex systems design.…

Other Computer Science · Computer Science 2010-04-20 Antonio Cimino , Francesco Longo , Giovanni Mirabelli

Accurate simulation of the printing process is essential for improving print quality, reducing waste, and optimizing the printing parameters of extrusion-based additive manufacturing. Traditional additive manufacturing simulations are very…

Graphics · Computer Science 2025-07-23 Dhruv Gamdha , Kumar Saurabh , Baskar Ganapathysubramanian , Adarsh Krishnamurthy

Foundation models are trained on a large amount of data to learn generic patterns. Consequently, these models can be used and fine-tuned for various purposes. Naturally, studying such models' use in the context of digital twins for…

Software Engineering · Computer Science 2025-07-03 Shaukat Ali , Paolo Arcaini , Aitor Arrieta

Digital twin (DT) enables smart manufacturing by leveraging real-time data, AI models, and intelligent control systems. This paper presents a state-of-the-art analysis on the emerging field of DTs in the context of milling. The critical…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Wenyi Liu , R. Sharma , W. "Grace" Guo , J. Yi , Y. B. Guo

Time-to-event (survival) analysis models the time until a pre-specified event occurs. When time is measured in discrete units or rounded into intervals, standard continuous-time models can yield biased estimators. In addition, the event of…

Machine Learning · Statistics 2025-11-19 Tomer Meir , Rom Gutman , Malka Gorfine

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

Machine Learning · Computer Science 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

Blockchain systems are challenged by the so-called Trilemma tradeoff: decentralization, scalability and security. Infrastructure and node configuration, choice of the Consensus Protocol and complexity of the application transactions are…

Cryptography and Security · Computer Science 2022-04-27 Georgios Diamantopoulos , Nikos Tziritas , Rami Bahsoon , Georgios Theodoropoulos

Particle tracking is commonly used to study time-dependent behavior in many different types of physical and chemical systems involving constituents that span many length scales, including atoms, molecules, nanoparticles, granular particles,…

Computational Physics · Physics 2024-08-06 Brandon L. Butler , Domagoj Fijan , Sharon C. Glotzer

Digital Twin is an emerging technology that replicates real-world entities into a digital space. It has attracted increasing attention in the transportation field and many researchers are exploring its future applications in the development…

Robotics · Computer Science 2023-04-07 Zijin Wang , Ou Zheng , Liangding Li , Mohamed Abdel-Aty , Carolina Cruz-Neira , Zubayer Islam

This short paper represents a systematic literature review that sets the basis for the future development of a framework for digital twin-based decision support in the public sector, specifically for the smart city domain. The final aim of…

Computers and Society · Computer Science 2024-06-03 Lucy Temple , Gabriela Viale Pereira , Lukas Daniel Klausner

Behavior models form an integral component of Digital Twins. The specific characteristics of these models may vary depending on the use case. One of these key characteristics is the modeling depth. Behavior models with a lower modeling…

Systems and Control · Electrical Eng. & Systems 2024-11-13 Valentin Stegmaier , Walter Schaaf , Nasser Jazdi , Michael Weyrich

Process mining techniques including process discovery, conformance checking, and process enhancement provide extensive knowledge about processes. Discovering running processes and deviations as well as detecting performance problems and…

Other Computer Science · Computer Science 2021-08-05 Mahsa Pourbafrani , Shuai Jiao , Wil M. P. van der Aalst

Future manufacturing requires complex systems that connect simulation platforms and virtualization with physical data from industrial processes. Digital twins incorporate a physical twin, a digital twin, and the connection between the two.…

Machine Learning · Computer Science 2021-09-20 Trier Mortlock , Deepan Muthirayan , Shih-Yuan Yu , Pramod P. Khargonekar , Mohammad A. Al Faruque

Inspired by the increased cooperation between humans and autonomous systems, we present a new hybrid systems framework capturing the interconnected dynamics underlying these interactions. The framework accommodates models arising from both…

Robotics · Computer Science 2025-10-13 Daniel A. Williams , Airlie Chapman , Chris Manzie

The Cloud-Edge continuum enhances application performance by bringing computation closer to data sources. However, it presents considerable challenges in managing resources and determining service placement, as these tasks require…

Networking and Internet Architecture · Computer Science 2026-01-27 Jacopo Massa , Valerio De Caro , Stefano Forti , Patrizio Dazzi , Davide Bacciu , Antonio Brogi

Background: Advances in the theory and methods of computational oncology have enabled accurate characterization and prediction of tumor growth and treatment response on a patient-specific basis. This capability can be integrated into a…

Digital twins have recently gained significant interest in simulation, optimization, and predictive maintenance of Industrial Control Systems (ICS). Recent studies discuss the possibility of using digital twins for intrusion detection in…

Cryptography and Security · Computer Science 2022-07-21 Seba Anna Varghese , Alireza Dehlaghi Ghadim , Ali Balador , Zahra Alimadadi , Panos Papadimitratos

Currently, most of the research in digital twins focuses on simulation and optimization. Digital twins are especially useful for critical systems. However, digital twins can also be used for safety and cyber security. The idea of this paper…

Cryptography and Security · Computer Science 2022-05-02 Tianyu Zhao , Ernest Foo , Hui Tian
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