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The generation of high-quality synthetic data presents significant challenges in machine learning research, particularly regarding statistical fidelity and uncertainty quantification. Existing generative models produce compelling synthetic…

Machine Learning · Computer Science 2025-05-13 Rahul Vishwakarma , Shrey Dharmendra Modi , Vishwanath Seshagiri

The development of accurate medical image classification models is often constrained by privacy concerns and data scarcity for certain conditions, leading to small and imbalanced datasets. To address these limitations, this study explores…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Iman Khazrak , Shakhnoza Takhirova , Mostafa M. Rezaee , Mehrdad Yadollahi , Robert C. Green , Shuteng Niu

Simulating human profiles by instilling personas into large language models (LLMs) is rapidly transforming research in agentic behavioral simulation, LLM personalization, and human-AI alignment. However, most existing synthetic personas…

Artificial Intelligence · Computer Science 2025-12-02 Zhen Wang , Yufan Zhou , Zhongyan Luo , Lyumanshan Ye , Adam Wood , Man Yao , Saab Mansour , Luoshang Pan

Synthetic data is being used lately for training deep neural networks in computer vision applications such as object detection, object segmentation and 6D object pose estimation. Domain randomization hereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Parth Rawal , Mrunal Sompura , Wolfgang Hintze

Synthetic population generation is the process of combining multiple socioeconomic and demographic datasets from different sources and/or granularity levels, and downscaling them to an individual level. Although it is a fundamental step for…

Machine Learning · Computer Science 2019-11-12 Colin Wan , Zheng Li , Alicia Guo , Yue Zhao

In recent years, optimization in the learned latent space of deep generative models has been successfully applied to black-box optimization problems such as drug design, image generation or neural architecture search. Existing models…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Steffen Jung , Jan Christian Schwedhelm , Claudia Schillings , Margret Keuper

Deep Generative models (DGMs) play two key roles in modern machine learning: (i) producing new information (e.g., image synthesis) and (ii) reducing dimensionality. However, traditional architectures often rely on auxiliary networks such as…

Machine Learning · Computer Science 2026-02-23 Georgi Hrusanov , Oliver Y. Chén , Julien S. Bodelet

Deep Generative Machine Learning Models (DGMs) have been growing in popularity across the design community thanks to their ability to learn and mimic complex data distributions. DGMs are conventionally trained to minimize statistical…

Machine Learning · Computer Science 2022-06-16 Lyle Regenwetter , Faez Ahmed

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

Research and education in machine learning needs diverse, representative, and open datasets that contain sufficient samples to handle the necessary training, validation, and testing tasks. Currently, the Recommender Systems area includes a…

Information Retrieval · Computer Science 2023-03-03 Jesús Bobadilla , Abraham Gutiérrez , Raciel Yera , Luis Martínez

Deep generative models such as Variational Autoencoders (VAEs), Generative Adversarial Networks (GANs), Diffusion Models, and Transformers, have shown great promise in a variety of applications, including image and speech synthesis, natural…

Machine Learning · Computer Science 2025-11-18 Lyle Regenwetter , Akash Srivastava , Dan Gutfreund , Faez Ahmed

We combine hierarchical Bayesian modeling with a flow-based deep generative network, in order to demonstrate that one can efficiently constraint numerical gravitational wave (GW) population models at a previously intractable complexity.…

Instrumentation and Methods for Astrophysics · Physics 2020-07-07 Kaze W. K. Wong , Gabriella Contardo , Shirley Ho

Deep generative models (DGMs) have the potential to revolutionize diagnostic imaging. Generative adversarial networks (GANs) are one kind of DGM which are widely employed. The overarching problem with deploying GANs, and other DGMs, in any…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rucha Deshpande , Mark A. Anastasio , Frank J. Brooks

Affective computing faces a major challenge: the lack of high-quality, diverse depth facial datasets for recognizing subtle emotional expressions. We propose a framework for synthetic depth face generation using an optimized GAN with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Seyed Muhammad Hossein Mousavi , S. Younes Mirinezhad

Artificial data synthesis is currently a well studied topic with useful applications in data science, computer vision, graphics and many other fields. Generating realistic data is especially challenging since human perception is highly…

Computational Geometry · Computer Science 2019-01-23 Gil Shamai , Ron Slossberg , Ron Kimmel

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

The sharing of medical imaging datasets between institutions, and even inside the same institution, is limited by various regulations/legal barriers. Although these limitations are necessities for protecting patient privacy and setting…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Engin Dikici , Luciano M. Prevedello , Matthew Bigelow , Richard D. White , Barbaros Selnur Erdal

Generating virtual populations of anatomy that capture sufficient variability while remaining plausible is essential for conducting in-silico trials of medical devices. However, not all anatomical shapes of interest are always available for…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Haoran Dou , Seppo Virtanen , Nishant Ravikumar , Alejandro F. Frangi

Electronic health records (EHR) often contain different rates of representation of certain subpopulations (SP). Factors like patient demographics, clinical condition prevalence, and medical center type contribute to this…

Machine Learning · Computer Science 2024-03-12 Oriel Perets , Nadav Rappoport

There is a need for synthetic training and test datasets that replicate statistical distributions of original datasets without compromising their confidentiality. A lot of research has been done in leveraging Generative Adversarial Networks…

Machine Learning · Computer Science 2026-02-06 Laura Plein , Alexi Turcotte , Arina Hallemans , Andreas Zeller