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Related papers: Understanding Dynamics in Coarse-Grained Models: I…

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Coarse grain (CG) molecular dynamics (MD) can simulate systems inaccessible to fine grain (FG) MD simulations. A CG simulation decreases the degrees of freedom by mapping atoms from an FG representation into agglomerate CG particles. The FG…

Chemical Physics · Physics 2018-10-08 Maghesree Chakraborty , Chenliang Xu , Andrew D. White

Machine-learned (ML) coarse-grained (CG) models are a promising tool for significantly enhancing the efficiency of molecular simulations by systematically removing degrees of freedom while retaining fidelity to the underlying fine-grained…

Chemical Physics · Physics 2026-02-27 Patrick G. Sahrmann , Benjamin T. Nebgen , Kipton Barros , Brenden W. Hamilton

Entropy production is arguably the most universally applicable measure of non-equilibrium behavior, particularly for systems coupled to a heat bath. This setting encompasses driven soft matter as well as biomolecular, biochemical, and…

Statistical Mechanics · Physics 2025-12-09 Udo Seifert

By reducing resolution, coarse-grained models greatly accelerate molecular simulations, unlocking access to long-timescale phenomena, though at the expense of microscopic information. Recovering this fine-grained detail is essential for…

Chemical Physics · Physics 2026-03-27 Sander Hummerich , Tristan Bereau , Ullrich Köthe

A microscopic understanding of low-temperature thermodynamics and its relation to dynamical features such as a fragile-to-strong crossover (FSC) remains a central challenge in glass physics. Using swap Monte Carlo combined with a full…

Soft Condensed Matter · Physics 2026-05-25 Anshul D. S. Parmar , Simon G. Kellers , Andreas Heuer

A persistent challenge in predictive molecular modeling of thermoset polymers is to capture the effects of chemical composition and degree of crosslinking (DC) on dynamical and mechanical properties with high computational efficiency. We…

Soft Condensed Matter · Physics 2021-10-15 Andrea Giuntoli , Nitin K. Hansoge , Anton van Beek , Zhaoxu Meng , Wei Chen , Sinan Keten

High-dimensional recordings of dynamical processes are often characterized by a much smaller set of effective variables, evolving on low-dimensional manifolds. Identifying these latent dynamics requires solving two intertwined problems:…

Machine Learning · Computer Science 2026-01-21 Manuel Hinz , Maximilian Mauel , Patrick Seifner , David Berghaus , Kostadin Cvejoski , Ramses J. Sanchez

Stochastic modelling of complex systems plays an essential, yet often computationally intensive role across the quantitative sciences. Recent advances in quantum information processing have elucidated the potential for quantum simulators to…

Quantum Physics · Physics 2021-06-22 Thomas J. Elliott

Coarse-grained (CG) modeling simplifies molecular systems by mapping groups of atoms into representative units. However, traditional CG approaches rely on fixed mapping rules, which limit their ability to handle diverse chemical systems and…

Computational Physics · Physics 2025-09-26 Zhixuan Zhong , Linbo Ma , Jian Jiang

Cellular regulatory dynamics is driven by large and intricate networks of interactions at the molecular scale, whose sheer size obfuscates understanding. In light of limited experimental data, many parameters of such dynamics are unknown,…

Quantitative Methods · Quantitative Biology 2014-04-30 Bryan C. Daniels , Ilya Nemenman

Quantum nanosystems such as graphene nanoribbons or superconducting nanoparticles are studied via a multiscale approach. Long space-time dynamics is derived using a perturbation expansion in the ratio of the nearest-neighbor distance to a…

Quantum Physics · Physics 2011-03-10 Zeina Shreif , Peter Ortoleva

Simulations of condensed matter systems often focus on the dynamics of a few distinguished components but require integrating the dynamics of the full system. A prime example is a molecular dynamics simulation of a (macro)molecule in…

Computational Physics · Physics 2024-03-12 Mauricio J. del Razo , Daan Crommelin , Peter G. Bolhuis

Bottom-up coarse-grained molecular dynamics models are parameterized using complex effective Hamiltonians. These models are typically optimized to approximate high dimensional data from atomistic simulations. In contrast, human validation…

Chemical Physics · Physics 2021-09-16 Aleksander Evren Paetzold Durumeric , Gregory A. Voth

Microstructural evolution in structural materials is known to occur in response to mechanical loading and can often accommodate substantial plastic deformation through the coupled motion of grain boundaries (GBs). This can produce desirable…

Mesoscale and Nanoscale Physics · Physics 2025-06-06 Daniel Bugas , Brandon Runnels

In recent papers, we have argued that kinetically constrained coarse grained models can be applied to understand dynamic properties of glass forming materials, and we have used this approach in various applications that appear to validate…

Statistical Mechanics · Physics 2009-11-11 David Chandler , Juan P. Garrahan

Dissipative particle dynamics (DPD) is now a well-established method for simulating soft matter systems. However, its applicability was recently questioned because some investigations showed an upper coarse-graining limit that would prevent…

Soft Condensed Matter · Physics 2011-11-09 Rudolf M. Füchslin , Harold Fellermann , Anders Eriksson , Hans-Joachim Ziock

The dynamics of real magnets is often governed by several interacting processes taking place simultaneously at different length scales. For dynamical simulations the relevant length scales should be coupled, and the energy transfer…

Materials Science · Physics 2007-05-23 V. V. Dobrovitski , M. I. Katsnelson , B. N. Harmon

Multi-view subspace clustering (MSC) is a popular unsupervised method by integrating heterogeneous information to reveal the intrinsic clustering structure hidden across views. Usually, MSC methods use graphs (or affinity matrices) fusion…

Machine Learning · Computer Science 2023-08-15 Yidi Wang , Xiaobing Pei , Haoxi Zhan

Transient bonds between fast linkers and slower particles are widespread in physical and biological systems. In spite of their diverse structure and function, a commonality is that the linkers diffuse on timescales much faster compared to…

Soft Condensed Matter · Physics 2023-06-06 Sophie Marbach , Christopher E. Miles

We discuss the role coarse-grained models play in the investigation of the structure and thermodynamics of bilayer membranes, and we place them in the context of alternative approaches. Because they reduce the degrees of freedom and employ…

Soft Condensed Matter · Physics 2009-11-11 Marcus Mueller , Kirill Katsov , Michael Schick