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Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

With the advancement of powerful image processing and machine learning techniques, CAD has become ever more prevalent in all fields of medicine including ophthalmology. Since optic disc is the most important part of retinal fundus image for…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Muhammad Naseer Bajwa , Muhammad Imran Malik , Shoaib Ahmed Siddiqui , Andreas Dengel , Faisal Shafait , Wolfgang Neumeier , Sheraz Ahmed

Visual field tests (VFT) are pivotal for glaucoma diagnosis and conducted regularly to monitor disease progression. Here we address the question to what degree aggregate VFT measurements such as Visual Field Index (VFI) and Mean Deviation…

Computer Vision and Pattern Recognition · Computer Science 2019-10-11 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel Schuman , Rahil Garnavi

Although unprecedented sensitivity and specificity values are reported, recent glaucoma detection deep learning models lack in decision transparency. Here, we propose a methodology that advances explainable deep learning in the field of…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Ruben Hemelings , Bart Elen , João Barbosa-Breda , Matthew B. Blaschko , Patrick De Boever , Ingeborg Stalmans

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

Fairness (also known as equity interchangeably) in machine learning is important for societal well-being, but limited public datasets hinder its progress. Currently, no dedicated public medical datasets with imaging data for fairness…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Yan Luo , Yu Tian , Min Shi , Louis R. Pasquale , Lucy Q. Shen , Nazlee Zebardast , Tobias Elze , Mengyu Wang

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Aniketh Manjunath , Subramanya Jois , Chandra Sekhar Seelamantula

Ear disease contributes significantly to global hearing loss, with recurrent otitis media being a primary preventable cause in children, impacting development. Artificial intelligence (AI) offers promise for early diagnosis via otoscopic…

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Gauri Naik , Nandini Narvekar , Dimple Agarwal , Nishita Nandanwar , Himangi Pande

Cataracts are the leading cause of visual impairment and blindness globally. Over the years, researchers have achieved significant progress in developing state-of-the-art machine learning techniques for automatic cataract classification and…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Xiaoqing Zhang , Yan Hu , Zunjie Xiao , Jiansheng Fang , Risa Higashita , Jiang Liu

Glaucoma is a severe eye disease that is known to deteriorate optic never fibers, causing cup size to increase, which could result in permanent loss of vision. Glaucoma is the second leading cause of blindness after cataract, but glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Maleeha Khalid Khan , Syed Muhammad Anwar

Retinal Optical Coherence Tomography (OCT), a noninvasive cross-sectional scan of the eye with qualitative 3D visualization of the retinal anatomy is use to study the retinal structure and the presence of pathogens. The advent of the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

One of the leading causes of blindness is glaucoma, which is challenging to detect since it remains asymptomatic until the symptoms are severe. Thus, diagnosis is usually possible until the markers are easy to identify, i.e., the damage has…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Sayan Mandal , Alessandro A. Jammal , Felipe A. Medeiros

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yiran Song , Yikai Zhang , Silvia Orengo-Nania , Nian Wang , Fenglong Ma , Rui Zhang , Yifan Peng , Mingquan Lin

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović