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Accurate diagnosis of glaucoma is challenging, as early-stage changes are subtle and often lack clear structural or appearance cues. Most existing approaches rely on a single modality, such as fundus or optical coherence tomography (OCT),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhiwei Wang , Yuxing Li , Meilu Zhu , Defeng He , Edmund Y. Lam

Glaucoma leads to permanent vision disability by damaging the optical nerve that transmits visual images to the brain. The fact that glaucoma does not show any symptoms as it progresses and cannot be stopped at the later stages, makes it…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Ozer Can Devecioglu , Junaid Malik , Turker Ince , Serkan Kiranyaz , Eray Atalay , Moncef Gabbouj

The diagnosis of glaucoma plays a critical role in the management and treatment of this vision-threatening disease. Glaucoma is a group of eye diseases that cause blindness by damaging the optic nerve at the back of the eye. Often called…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yuki Hagiwara , Octavia-Andreea Ciora , Maureen Monnet , Gino Lancho , Jeanette Miriam Lorenz

Glaucoma remains among the leading causes of blindness despite many treatment options available today. Effective treatment requires early diagnosis, which is difficult to achieve with existing imaging technologies that detect the already…

Purpose: (1) To assess the performance of geometric deep learning (PointNet) in diagnosing glaucoma from a single optical coherence tomography (OCT) 3D scan of the optic nerve head (ONH); (2) To compare its performance to that obtained with…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Alexandre H. Thiery , Fabian Braeu , Tin A. Tun , Tin Aung , Michael J. A. Girard

Glaucoma is a chronic neurodegenerative condition that can lead to blindness. Early detection and curing are very important in stopping the disease from getting worse for glaucoma patients. The 2D fundus images and optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Wenyun Li , Chi-Man Pun

Glaucomatous optic neuropathy (GON) is a prevalent ocular disease that can lead to irreversible vision loss if not detected early and treated. The traditional diagnostic approach for GON involves a set of ophthalmic examinations, which are…

Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Artem Sevastopolsky

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yuzhuo Zhou , Chi Liu , Sheng Shen , Siyu Le , Liwen Yu , Sihan Ouyang , Zongyuan Ge

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Glaucoma is one of the leading causes of irreversible but preventable blindness in working age populations. Color fundus photography (CFP) is the most cost-effective imaging modality to screen for retinal disorders. However, its application…

The optic nerve head (ONH) typically experiences complex neural- and connective-tissue structural changes with the development and progression of glaucoma, and monitoring these changes could be critical for improved diagnosis and prognosis…

Background/Aims: Standard Automated Perimetry (SAP) is the gold standard to monitor visual field (VF) loss in glaucoma management, but is prone to intra-subject variability. We developed and validated a deep learning (DL) regression model…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Ruben Hemelings , Bart Elen , João Barbosa Breda , Erwin Bellon , Matthew B Blaschko , Patrick De Boever , Ingeborg Stalmans

Subject of research: is the study of methods for analyzing perimetric images for the diagnosis and control of glaucoma diseases. Objects of research: is a dataset collected on the ophthalmological perimeter with the results of various…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 A. I. Medvedeva , V. V. Bakutkin

Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Zhiyuan Cai , Li Lin , Huaqing He , Xiaoying Tang

Automated Computer Aided diagnostic tools can be used for the early detection of glaucoma to prevent irreversible vision loss. In this work, we present a Multi-task Convolutional Neural Network (CNN) that jointly segments the Optic Disc…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Arunava Chakravarty , Jayanthi Sivswamy

Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Shujun Wang , Lequan Yu , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

GAMMA Challenge is organized to encourage the AI models to screen the glaucoma from a combination of 2D fundus image and 3D optical coherence tomography volume, like the ophthalmologists.

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Junde Wu , Huihui Fang , Fei Li , Huazhu Fu , Yanwu Xu

Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Fabian A. Braeu , Alexandre H. Thiéry , Tin A. Tun , Aiste Kadziauskiene , George Barbastathis , Tin Aung , Michaël J. A. Girard

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…