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This review paper explores recent advances in deep learning approaches for non-invasive cognitive impairment detection. We examine various non-invasive indicators of cognitive decline, including speech and language, facial, and motoric…

Machine Learning · Computer Science 2025-04-16 Muath Alsuhaibani , Ali Pourramezan Fard , Jian Sun , Farida Far Poor , Peter S. Pressman , Mohammad H. Mahoor

Deep neural network training often involves stochastic optimization, meaning each run will produce a different model. This implies that hyperparameters of the training process, such as the random seed itself, can potentially have…

Machine Learning · Statistics 2025-04-17 Sinjini Banerjee , Tim Marrinan , Reilly Cannon , Tony Chiang , Anand D. Sarwate

Machine learning methods exploiting multi-parametric biomarkers, especially based on neuroimaging, have huge potential to improve early diagnosis of dementia and to predict which individuals are at-risk of developing dementia. To benchmark…

Machine Learning · Computer Science 2022-02-21 Esther E. Bron , Stefan Klein , Annika Reinke , Janne M. Papma , Lena Maier-Hein , Daniel C. Alexander , Neil P. Oxtoby

Early detection of suicidal ideation in depressed individuals can allow for adequate medical attention and support, which in many cases is life-saving. Recent NLP research focuses on classifying, from a given piece of text, if an individual…

Machine Learning · Computer Science 2021-06-23 Ayaan Haque , Viraaj Reddi , Tyler Giallanza

Depression is a leading cause of death worldwide, and the diagnosis of depression is nontrivial. Multimodal learning is a popular solution for automatic diagnosis of depression, and the existing works suffer two main drawbacks: 1) the…

Multimedia · Computer Science 2023-01-03 Chengbo Yuan , Qianhui Xu , Yong Luo

Variable importance assessment has become a crucial step in machine-learning applications when using complex learners, such as deep neural networks, on large-scale data. Removal-based importance assessment is currently the reference…

Machine Learning · Computer Science 2023-10-27 Ahmad Chamma , Denis A. Engemann , Bertrand Thirion

Depression is a common disease worldwide. It is difficult to diagnose and continues to be underdiagnosed. Because depressed patients constantly share their symptoms, major life events, and treatments on social media, researchers are turning…

Computation and Language · Computer Science 2025-10-27 Wenli Zhang , Jiaheng Xie , Zhu Zhang , Xiang Liu

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Student diversity, like academic background, learning styles, career and life goals, ethnicity, age, social and emotional characteristics, course load and work schedule, offers unique opportunities in education, like learning new skills,…

Computers and Society · Computer Science 2022-05-02 Alex Doboli , Simona Doboli , Ryan Duke , Sangjin Hong , Wendy Tang

Large-scale black-box models have become ubiquitous across numerous applications. Understanding the influence of individual training data sources on predictions made by these models is crucial for improving their trustworthiness. Current…

Machine Learning · Computer Science 2024-06-21 Myeongseob Ko , Feiyang Kang , Weiyan Shi , Ming Jin , Zhou Yu , Ruoxi Jia

We analyze the data-dependent capacity of neural networks and assess anomalies in inputs from the perspective of networks during inference. The notion of data-dependent capacity allows for analyzing the knowledge base of a model populated…

Machine Learning · Computer Science 2023-04-13 Jinsol Lee , Charlie Lehman , Mohit Prabhushankar , Ghassan AlRegib

Researchers often have datasets measuring features $x_{ij}$ of samples, such as test scores of students. In factor analysis and PCA, these features are thought to be influenced by unobserved factors, such as skills. Can we determine how…

Statistics Theory · Mathematics 2019-09-16 Edgar Dobriban

Causal inference in longitudinal biomedical data remains a central challenge, especially in psychiatry, where symptom heterogeneity and latent confounding frequently undermine classical estimators. Most existing methods for treatment effect…

Machine Learning · Computer Science 2025-07-28 Eric V. Strobl

Background and objective: Diabetes is a chronic pathology which is affecting more and more people over the years. It gives rise to a large number of deaths each year. Furthermore, many people living with the disease do not realize the…

Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective,…

Artificial Intelligence · Computer Science 2026-05-01 Dorsa Macky Aleagha , Payam Zohari , Mostafa Haghir Chehreghani

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Recent advancements in semi-supervised deep learning have introduced effective strategies for leveraging both labeled and unlabeled data to improve classification performance. This work proposes a semi-supervised framework that utilizes a…

Machine Learning · Computer Science 2025-05-21 Aydin Abedinia , Shima Tabakhi , Vahid Seydi

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

Interpreting the performance of deep learning models beyond test set accuracy is challenging. Characteristics of individual data points are often not considered during evaluation, and each data point is treated equally. We examine the…

Computation and Language · Computer Science 2018-09-11 John P. Lalor , Hao Wu , Tsendsuren Munkhdalai , Hong Yu
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