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Grids enable the aggregation, virtualization and sharing of massive heterogeneous and geographically dispersed resources, using files, applications and storage devices, to solve computation and data intensive problems, across institutions…
Generalized linear and additive models are very efficient regression tools but the selection of relevant terms becomes difficult if higher order interactions are needed. In contrast, tree-based methods also known as recursive partitioning…
Revealing the functional sites of biological sequences, such as evolutionary conserved, structurally interacting or co-evolving protein sites, is a fundamental, and yet challenging task. Different frameworks and models were developed to…
The Federated Learning paradigm facilitates effective distributed machine learning in settings where training data is decentralized across multiple clients. As the popularity of the strategy grows, increasingly complex real-world problems…
Component-based software engineering aims to reduce software development effort by reusing established components as building blocks of complex systems. Defining components in general-purpose programming languages restricts their reuse to…
In order to behave intelligently both humans and machines have to represent their knowledge adequately for how it is used. Humans often use analogies to transfer their knowledge to new domains, or help others with this transfer via…
Learning high-quality feature embeddings efficiently and effectively is critical for the performance of web-scale machine learning systems. A typical model ingests hundreds of features with vocabularies on the order of millions to billions…
Federated learning promises to revolutionize machine learning by enabling collaborative model training without compromising data privacy. However, practical adaptability can be limited by critical factors, such as the participation dilemma.…
The role of types in categorical models of meaning is investigated. A general scheme for how typed models of meaning may be used to compare sentences, regardless of their grammatical structure is described, and a toy example is used as an…
Discrete models have a long tradition in engineering, including finite state machines, Boolean networks, Petri nets, and agent-based models. Of particular importance is the question of how the model structure constrains its dynamics. This…
Fixed effects models are very flexible because they do not make assumptions on the distribution of effects and can also be used if the heterogeneity component is correlated with explanatory variables. A disadvantage is the large number of…
Complex models, such as neural networks (NNs), are comprised of many interrelated components. In order to represent these models, eliciting and characterising the relations between components is essential. Perhaps because of this, diagrams,…
Modeling is a central concern in both science and engineering. However, we need a new fundamental theory to address the challenges of the digital age. In this paper, we first explain why modeling is fundamental and which challenges must be…
This paper introduces a framework for studying the interactions of autonomous system components and the design of the connectivity structure in Systems of Systems (SoSs). This framework, which uses complex network models, is also used to…
Interventional causal models describe several joint distributions over some variables used to describe a system, one for each intervention setting. They provide a formal recipe for how to move between the different joint distributions and…
The study of representations is of fundamental importance to any form of communication, and our ability to exploit them effectively is paramount. This article presents a novel theory -- Representational Systems Theory -- that is designed to…
Applied category theory often studies symmetric monoidal categories (SMCs) whose morphisms represent open systems. These structures naturally accommodate complex wiring patterns, leveraging (co)monoidal structures for splitting and merging…
For a software system, its architecture is typically defined as the fundamental organization of the system incorporated by its components, their relationships to one another and their environment, and the principles governing their design.…
Solutions to decentralized discrete-event systems problems are characterized by the way local decisions are fused to yield a global decision. A fusion rule is colloquially called an architecture. Current approaches do not provide a direct…
This study explored the architecture of semantic segmentation and evaluated models that excel in polyp segmentation. We present an integrated framework that harnesses the advantages of different models to attain an optimal outcome.…