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Cerebral arterial blood flow (CABF) can be investigated in few seconds without any synchronization by Real-Time phase contrast. Significant changes in CABF were found between expiration and inspiration during normal breathing of healthy…
Compared with CINE phase contrast MRI (CINE-PC), echo-planar imaging phase contrast (EPI-PC) can achieve realtime quantification of blood flow, with lower SNR. In this study, the pulsating real model of the simulated cerebral vasculature…
Nasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational Fluid Dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a…
Cerebrospinal fluid (CSF) plays a pivotal role in normal functioning of Brain. Intracranial compartments such as blood, brain and CSF are incompressible in nature. Therefore, if a volume imbalance in one of the aforenoted compartments is…
Results of an experiment are presented whose aim is to explore the relationship between respiration and cerebral oxygenation. Measurements of end tidal CO2 (EtCO2) were taken simultaneously with cerebral oxygen saturation (rSO2) using the…
Modern MRI relies on the well-established Echo-Planar-Imaging (EPI) method for fast acquisition. EPI is the workhorse of diffusion and functional MRI in neuroscience as well as of many dynamic applications for clinical body imaging. Its…
A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…
Hydrocephalus is a neurological condition characterized by disturbed cerebrospinal fluid (CSF) dynamics and is typically treated with shunt systems that drain excessive CSF out of the ventricular system. Continuous monitoring of ventricular…
In this paper we provide the numerical simulations of two cerebrospinal fluid dynamics models by comparing our results with the real data available in literature. The models describe different processes in the cerebrospinal fluid dynamics:…
Numerous mathematical models have emerged in the medical literature over the past two decades attempting to characterize the pressure and volume dynamics the central nervous system compartment. These models have been used to study he…
Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…
Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…
A healthy human brain is perfused with blood flowing laminarly through cerebral vessels, providing brain tissue with substrates such as oxygen and glucose. Under normal conditions, cerebral blood flow is controlled by autoregulation as well…
Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…
We apply the lubrication approximation to solve for the flow generated by a peristaltic traveling wave in a finite, planar channel, and examine the effect of channel length. Cerebrospinal fluid (CSF) is hypothesized to be peristaltically…
Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…
We tested the hypothesis that simple exercises may significantly increase cerebral blood flow (CBF) and/or cerebral oxygenation. Eighteen subjects ranging in age from nineteen to thirty nine participated in a four-stage study during which…
Flow 2.0 is an end-to-end easy-of-use software that allows us to quickly, robustly and accurately perform a batch process real-time phase contrast data and multivariate analysis of the effect of respiration on cerebral fluids circulation.…
Airflow through the nasal cavity exhibits a wide variety of fluid dynamicsbehaviour due to the intricacy of the nasal geometry. The flow is naturallyunsteady and perhaps turbulent, despite CFD in the literature that assumesa steady laminar…
This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed…