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Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by…

Machine Learning · Computer Science 2019-04-23 Marysia Winkels , Taco S. Cohen

In this paper, we present a new statistical approach to automatically identify cancer regions in pathological images. The proposed method is built from statistical theory in line with evidence-based medicine. The two core technologies are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Toshiki Kindo

Variation in nuclear size and shape is an important criterion of malignancy for many tumor types; however, categorical estimates by pathologists have poor reproducibility. Measurements of nuclear characteristics (morphometry) can improve…

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images with 1.25 mm slice thickness is presented. The basic modules of our lung-CAD system, a…

Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…

In the first step, a pre-trained model (YOLO) was used to detect all suspicious nod-ules. The YOLO model was re-trained using 397 CT images to detect the entire nodule in CT images. To maximize the sensitivity of the model, a confidence…

Medical Physics · Physics 2022-12-20 Yashar Ahmadyar Razlighi , Alireza Kamali-Asl , Hossein Arabi

Automatic segmentation of head and neck cancer (HNC) tumors and lymph nodes plays a crucial role in the optimization treatment strategy and prognosis analysis. This study aims to employ nnU-Net for automatic segmentation and radiomics for…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Hui Xu , Yihao Li , Wei Zhao , Gwenolé Quellec , Lijun Lu , Mathieu Hatt

We propose new methods for the prediction of 5-year mortality in elderly individuals using chest computed tomography (CT). The methods consist of a classifier that performs this prediction using a set of features extracted from the CT image…

Computer Vision and Pattern Recognition · Computer Science 2016-10-04 Gustavo Carneiro , Luke Oakden-Rayner , Andrew P. Bradley , Jacinto Nascimento , Lyle Palmer

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on…

Computer Vision and Pattern Recognition · Computer Science 2015-11-12 Mohammad Javad Shafiee , Audrey G. Chung , Devinder Kumar , Farzad Khalvati , Masoom Haider , Alexander Wong

Lung cancer is a leading cause of cancer-related deaths worldwide, and early detection is crucial for improving patient outcomes. Nevertheless, early diagnosis of cancer is a major challenge, particularly in low-resource settings where…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Samiul Based Shuvo , Tasnia Binte Mamun

Longitudinal imaging analysis tracks disease progression and treatment response over time, providing dynamic insights into treatment efficacy and disease evolution. Radiomic features extracted from medical imaging can support the study of…

Applications · Statistics 2025-05-14 Isabella Cama , Michele Piana , Cristina Campi , Sara Garbarino

Objective: Although medical imaging datasets are increasingly available, abnormal and annotation-intensive findings critical to lung cancer screening, particularly small pulmonary nodules, remain underrepresented and inconsistently curated.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Fakrul Islam Tushar , Ehsan Samei , Cynthia Rudin , Joseph Y. Lo

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

Lesion segmentation is a crucial step of the radiomic workflow. Manual segmentation requires long execution time and is prone to variability, impairing the realisation of radiomic studies and their robustness. In this study, a deep-learning…

'Radiomics' is a method that extracts mineable quantitative features from radiographic images. These features can then be used to determine prognosis, for example, predicting the development of distant metastases (DM). Existing radiomics…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Yige Peng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

The purpose of this study is to develop a computer-aided diagnosis system for classifying benign and malignant lung lesions, and to assist physicians in real-time analysis of radial probe endobronchial ultrasound (EBUS) videos. During the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Ching-Kai Lin , Chin-Wen Chen , Yun-Chien Cheng

Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Anindo Saha , Fakrul I. Tushar , Khrystyna Faryna , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Geoffrey D. Rubin , Joseph Y. Lo

Radiomics has shown a capability for different types of cancers such as glioma to predict the clinical outcome. It can have a non-invasive means of evaluating the immunotherapy response prior to treatment. However, the use of deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Ahmad Chaddad , Mingli Zhang , Lama Hassan , Tamim Niazi

Purpose: This study evaluates the impact of harmonization and multi-region feature integration on survival prediction in non-small cell lung cancer (NSCLC) patients. We assess the prognostic utility of handcrafted radiomics and pretrained…